Contribution on the effect of ethyl-nor-testosterone and ethylene-nor-testosterone on various disturbances of the menstrual cycle

Contribution on the effect of ethyl-nor-testosterone and ethylene-nor-testosterone on various disturbances of the menstrual cycle

Volume 75 Number4 SELECTED Nold and Huber: lowing The effect results: The Itiuence of Chlorpromazine of chlorpromazine on labor 1. If labor is...

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Volume 75 Number4

SELECTED

Nold and Huber: lowing

The effect results:

The Itiuence

of Chlorpromazine

of chlorpromazine

on labor

1. If labor is well established, 2. If premature labor threatens, and Luminal can frequently

927

ABSTRACTS

was

contractions as shown be combined

on Labor, p. 1095. tested

by

tokodynamometer

with

the

fol-

are not affected by therapeutic dosage. by irregular contractions, chlorpromazine to avoid early termination of pregnancy.

WALTER F. TAUBER Vol.

79, July

$7, 1957.

Noldeke, Steffen,

R. : Contribution to the Diagnosis of Rupture of the Membranes, p. 1153. F. W.: Placental Fragment Retained in the Cervical Canal After Cesarean Section for Placenta Previa With Accretion Leading to Exsanguinating Hemorrhage, p, 1158. Rodecurt, M. : Injection of Homologous Blood and Calcium. Calcium Problems and the Treatment of Eclampsia, p. 1161. “Harbort, G. : Steroid Anesthesia in Obstetrics and Gynecology, p. 1172.

Harbort:

Steroid Anesthesia

in Obstetrics

and Gynecology,

p. 1172.

Based on Se’ye’s discovery that certain steroids have hypnotic and analgesic action, and on the fact that suecinates are not transmitted aeross the placenta, Pregnan-2191-3,29 dion-hemisuccinate sodium (Presuren) has been used on 165 patients undergoing obstetrical or gynecological operations. Twenty-three patients required no further anesthesia for such procedures as vaginal hysterectomy, radical vaginal hysterectomy, vaginal cesarean secOthers required only small amounts of nitrous oxide tion, and vaginal plastic operations. or ether.

WALTER F. TAUBER Vol.

79, August

3, 1957.

Besold,

F. : Historical and Psychological Pbservations on Factors Preventing Ovulation, p. 1189. on the Effect of Ethyl-Nor-Testosterone and Ethylene-Nor“Wasehlre, G. : Contribution Testosterone on Various Disturbances of the Menstrual Cycle, p. 1199. “Nyiri, I., Lampe, L., and Zsolnai, B.: Pituitary Gonadotropin Activity After Gyneeological Operations, p. 1210. Prolapse in a 19.Year-Old Secundigravida-A Case Report, Kramer, H. : Incomplete p. 1217. Three-year Experience With Medicinal Prophylaxis Against Thrombosis, Kosch, L.: p. 1221. and Labor in the Pathogenesis of Gynecological Kardos, F. : The Role of Pregnancy Tuberculosis, p. 1225.

Waschke: Contribution on the Effect Testosterone on Various Disturbances

of Ethyl-Nor-Testosterone and of the Menstrual Cycle, p. 1199.

Ethylene-Nor-

Both these 19-nor-testosterone compounds have progestational activity and are useful in the treatment of dysfunctions of the corpus luteum phase of the menstrual cycle. Prolonged bleeding due to excessive estrogen activity can be stopped in 24 to 48 hours by doses as low as 30 mg. In these cases endometrial hyperplasia is prevented by the use of these drugs. Amenorrhea due to deficiency in progesterone is readily terminated, though normal menstruation does not necessarily follow. Menopausal symptoms are well controlled without withdrawal bleeding. Hormone levels can be followed easily, for control of therapy, with basal temperature determinations and vaginal cytology.

WALTER F. TAUBER