Critical evaluation of Respiratory Sinus Arrhythmia (RSA) as a measure of cardiac Parasympathetic Control (PC)

emotionality discussed

with

lower

scores for good IIBP.

in the context

of different

The results

emotion

are

theories.

the night

period

in the

lower

in the third

not change CHANGES

IN

P300 AS A SIGN

TATION

IN VISUAL

P. Kolev.

D. Dalbokova.

OF COGNITIVE

CATEGORISATION

Institute

of Ilygiene ~a\

aimed

Health.

at Investigating

Sotia.

the

the

The

of

formatlon

task-relevant amined

dimension

as well.

categorisation sented

adaptation

Eight task.

the visual

The

stimuli

a short

Fz. c‘z and Pz. A significant

break

not

w’a\ found

differ

latency

with

between

in block

distance

model’

the

on

up with

EEG

task-relevant

was exvisual

were

two. The

therefore.

m\+N350) We

pre-

P300 3

regression

Pencho

OF ERP

AERP

Bulg.

Kolev.

Dafina of

Occupational

Dalhokova

Work

IIcalth.

Sofia.

pre\ent

the

event-related

visual

study

two only.

The

and latency reflect

potentials

(stimulus exhibiting

length)

by a large

negative

wave

of single

studying

of P.?-like

results

in the single

CATEGO-

of

categorization

task during I? right-handed

formed

with

five letters

Ilygiene

waves;

(200 ms duration)

crntre

of the

of the screen

\uhJects letters

were

instructed

were identical.

uli (target)

was within

were

delIvered

ment

covered

a I7

of four

and

h. EEG

4.30

number

showed

a probability h period

from

commencing

was recorded targets

wa

from

extrema

which

wcrc

were

not

was mainly of ERPs

AERP

phe-

slow wave: (2)

contribution

to the

of wave recognition waves were present

varied

components due

within

to NJ50

to the

registered

200 mb. The

observed

related

EVALUATION

in the

N4SO

development.

contribution

could

under

Kollai

of the

be useful

different

for the

conditions.

The method

of taking

ategoriza-

videomonitor.

The

activation

two subsequent In total

stim-

400 trials

of 6 s. The

experi-

13.00

h to

h.00

at

13.3,

18.30, 23.30

Fz, Cz and greater

h and

ing

as an index

hetwecn

level

of was

was related

was associated

individuals mean

rate

study

in conscious

not

influenced

the influence

The correlation

periods

to animal

RSA,

in IIP the

and

the

inputs

cycle length. but

whose

Slow hreathin different

on min. and max. HPa varied subjects

across subjects

but

hetween

as in a

data,

to zero.

by excitatory

augmented in some

from

(IIP)

as the change

reduced

to respiratory with

subjects

RSA was quantified

Aa opposed

PC wa

and pattern

was to test the

human

variability.

P<‘ was defined

HP was increased

others.

of PC’ was developed

max. and min. heart

cycle:

Icvel

Hungan

respiratory

aim of the present

a full dose of atropinc.

inspiratory

CARDIAC‘

(PC)

Budapest.

when

of respiratory

respiratory

after

RSA

of the method

the difference given

The

SINUS

OF

Mizsei

University.

animals,

constant.

a

under

CONTROL

Medical

in anaesthetized

RESPIRATORY

AS A MEASURE

and Gahor

the vlcwpoint

yra per-

OF

(RSA)

Scmmelweis

expiratory

Aignificantly

350

et al. 1989).

ERP slow, wave$. This approach

In

in

of two identical

intervals

(Kolev

formation

in the

of IO?.

(3) their

that slow negative

Their

regular

range

were presented

monochrome

The combination

sessions

of the missed

of conture

to press a key when

at interstimulus

consisted

performance

males aged 20-24

tion task. The stimuli

in

were

latency

01 that

A method

NJ50

Mark

and

the changes

the day and the night

the \ame length

origin

single

were

at Investigating

sleep deprivation.

(mean

of contributing

observed.

ERPs.

C‘RITICAL

Lasarov

In\tltutc

and

the

ERPs was applied

Our

AERPs

i\

the proper-

IN VISUAL

(ERP)

Bulgaria

were registered

condition.

at

lntcrpretation

Bulgaria

was aimed

Sci.. Sofia.

(AERPs)

(I) the characteristics

applicability The

AERPs

The ‘neuronal

and Prtko

Phy\iologq.

Acad.

potentials

phenomenon

latency

TASK

Department

DEVELOPMENT

IN CHILDREN’S

reaction

ARRHYTHMIA

VARIATIONS

did

and V. Silyamova

PARASYMPATHETIC DIURNAL

P300 latency

a choice

aimed

nomenon:

stow waves

tics of an AL.

RIZATION

wa+

at FI and Cz.

the presence

on

of the P.300 ampli-

continuum.

characterized

or in

that the P300 could

dimension

the experience.

under

to categoric\

at P/ in block

evidence

event-related

of category

curve of the P.700 amplitude on an inferred

Auditory

over Pz. The

trend

THE

WAVE

Institute.

children

in amplitude

in block

category

in the night.

STUDYING

J. Yordunova

Research

on the

was recorded

effect

either

quadratic

two gives further

the mental built

longer

with

(U-shape)

The main

TO

NEGATIVE

Helson

each of 250 trials

most expressed

significant

and latency

non-linear

length

of the P300 latency

significantly

showed

them.

of (AL)

bars)

blocks

the block\

the exception

and 5 being analysis

between

signals

was significantly

within

a five stimuli

(horizontal

from

tude

stimulus

at ISIS of 5 s in two identical

P300 amplitude

theory Level

sub.jects performed

with

did

level

of the Adaptation

Brain

between

and the processes ofcategoriaation

trameuork\

investigation

of detected

amplitude

Bulgaria

the relationship

the P300 component (1Yh-l).

P300

the time.

APPROACII

OF A SLOW

V. Kolev, The stud)

with

session.

ADAP-

and I’. Lasaro\

and Occupational

last

TASK AN

E. Dincheva

and the percentage

lower

so that

decreased

in

RSA and PC,

although

significant.

improved

when

was not close (r = 0.61 ). The correlation

Pz. The

included

as co-variables

(r = O.Y3). It

is concluded

during

con\ciou\

human

the respiratory

modulation

respiratory subjects

cycle length

and tidal volume

were

that

in

of PC is

47 different from that observed in anaesthetized animals, and that variations in RSA do not necessarily reflect proportional changes in PC.

on the right hands correlated positively auditory thresholds at 8000 Hz. Situational asymmetries are discussed.

AUTONOMIC, SOMATIC CHANGES PRECEDING PERFORMANCE

RESPIRATORY PATIENTS

AND BRAIN SLOW WAVE TIME-LOCKED SKILLFUL

N. Konttinen and H. Lyytinen University of JyvaskylaC, Jyvaskyla,

Maria S. Kopp and A. Temesviry Dept. of Psychiatry, Semmelweis Hungary

Finland

Autonomic, somatic and cortical slow wave responses were recorded from competitive marksmen (N = 12) while preparing for triggering a rifle. The present paper focuses on covariation patterns. Slow waves were recorded from midline (Fz, Cz and Oz) EEG-electrodes. Heart rate and respiration represented the autonomic and EMG from trapezius and subIimis muscles the somatic variables. The data consisted of 7.5 s pretrigger recording of these variables from at least 200 shots per subject. Consistent increases of slow wave negativity and heart rate deceleration occurred during the last seconds preceding the pulling of the trigger. Larger increases of frontocentral slow wave negativity were found during shots preceded by heart rate deceleration compared to no-HR-change trials. Also shots preceded by larger trapezius EMG increases revealed larger slow wave negativity.

ELECTRODERMAL ANXIETY PATIENT

LATERAL ASYMMETRIES GROUPS AND CONTROLS

Maria S. Kopp, Patrik Semmelweis Medical dapest, Hungary

Buza University,

Dept.

CONTROL

of Psychiatry.

IN

with the influences

TREATMENT

Medical

OF

School,

left-ear on ed.

PANIC

Budapest,

87 patients with panic syndrome or agoraphobia with panic were treated by the modified version of respiratory control treatment of Salkovskis and Clark. Outcome measures included anxiety and panic frequency diaries and autonomic measurements. Respiratory rate, transcutaneous arterial CO, tension, heart rate, electrodermal responses, surface integrated EMG were documented in patients and in 12 controls undergoing hyperventilation provocation tests and in patients before and after treatment. At the end of the sixth week of the therapy the decrease in attacks per week showed a highly significant negative correlation with the sixth week resting respiratory rate, and a positive correlation with the transcutaneous COz level. Before treatment the resting respiratory rate of patients was significantly higher compared to controls. The hyperventilation induced arterial CO, tension and heart rate responses were more pronounced and prolonged in panic patients than in controls. As for the effect of respiratory control treatment there was a significant increase in transcutaneous COZ in patients. These results support the central role of respiratory control methods in preventing panic attacks.

Bu-

Bilateral electrodermal ted.1 response amplitudes, nonspecific ed. responses and auditory thresholds were recorded in 41 panic patients, in 23 generalized anxiety (G.A.) patients and in 18 controls. After 7 min of relaxation subjects were presented a set of 10 verbal stimuli and three 95 dB auditory stimuli. Ed. response amplitudes to the first verbal stimulus on the right hand correlated positively with the right-ear auditory thresholds at 8000 Hz in both patient groups. In contrast to the panic patients and controls G.A. patients responded with higher right- than left-hand ed. responses to the first verbal stimulus. The bilateral resting nonspecific ed. activity was significantly more pronounced in G.A. patients than in panic patients and in controls. In panic groups the resting nonspecific ed. activity was higher on the left hand. At 8000 Hz panic and G.A. patients showed opposite asymmetries of auditory thresholds with a left-ear advantage for G.A. and a right-ear advantage for panic patients. These results suggest a relative right hemispheric activation dominance in G.A. patients compared to panic patients and controls. Ed. response amplitudes to the first, unexpected auditory stimulus

ARTIFICIAL MATERNAL AND IMMUNE FUNCTION L. Koranyi, Postgraduate

BEHAVIOR,

HORMONES

Sz. Walentin and E. Endroczi Medical School, Budapest, Hungary

Rosenblatt’s technique was used to induce maternal behavior (MB) in virgin female and in male rats. Sensory signals in the form of pup presentation elicited behavioral and hormonal changes in adult animals. The first exposure reduced avoidance of pups and activation of pituitaryadrenocortical system. The completely developed MB was accompanied by moderate prolactin (PRL) release in female but not in male rats. The question was raised how pup-induced catecholamine and PRL release modified the activity of dipeptidyl peptidase IV, DP IV. in T-cell suspension of adrenalectomized Wistar rats. It was found that in the avoidance phase the DP IV activity change could be prevented by propranolol pretreatment. PRL released during artifical MB resulted in an increase of DP IV activity, which did not develop following dopaminergic manipulations. Our studies suggest that olfactory and auditory stim-