Cross-Differentiation from the CD8 Lineage to CD4 T Cells in the Gut-Associated Microenvironment with a Nonessential Role of Microbiota

Cell Reports

Erratum Cross-Differentiation from the CD8 Lineage to CD4 T Cells in the Gut-Associated Microenvironment with a Nonessential Role of Microbiota Jen Bon Lui, Priyadharshini Devarajan, Sarah A. Teplicki, and Zhibin Chen* *Correspondence: [email protected] http://dx.doi.org/10.1016/j.celrep.2015.06.039

(Cell Reports 10, Issue 4, February 3, 2015; pp 574–585) In the originally published version of this article, although the results were correctly described in the text, the labels for the lower right panel of Figure 6B had been mistakenly transposed during the preparation for final submission. The corrected figure is provided below and now appears within the article online as well. The authors apologize for any confusion the error may have caused.

1844 Cell Reports 11, 1844–1845, June 23, 2015 ª2015 The Authors

0.2

OT1+Rago Foxp3+ 0.1

OT1+Rago Foxp3sf 3.1

MLN

0.1

OT1+Rago Foxp3sf

Activated CD8+ (%)

OT1+Rago Foxp3+

*** ***

4wk-old , Gated CD3+CD8+ 9wk-old , Gated CD3+CD8+

Foxp3sf

4

*

Foxp3+

A

40

2

20

0

0 **

Activated CD8+ #

13.4

CD44

Spleen

**

0.3

CD62L

*

5

**

0.2

107

105

106 103

105

10 0

104 4wk 9-11wk MLN

4wk 9-11wk Spleen

B

**

Weight (% original)

OT1+RagoFoxp3sf 100 80

60 0

Day 6 n=3 each

2 4 DSS

6

8

Days

100 Survival (%)

Post Tx n=4 each

**

No Tx n=5 each

OT1+RagoFoxp3+

OT1+RagoFoxp3sf

*

OT1+RagoFoxp3+

50

p < 0.05

0 0

2

4 6 DSS

8 10 12 14 Days

Figure 6

Cell Reports 11, 1844–1845, June 23, 2015 ª2015 The Authors 1845