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Cryptococcus meningitis treated with amphotericin B
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Correspondence
demonstration and diagnosis and "third priority" in respect to survival. It may be noted that the infant in our case was less than 72 hours old at the time of the operation. Since a complete review of the literature was not undertaken, we cannot be sure that some other cases of this rare condition in the newborn, with diagnosis and survival, have not been recorded. The importance of early diagnosis and therapy cannot be overemphasized. Three of the 9 patients alluded to in the paper by Drs.
July 1962
Dorsey, Hohf, and Lynn were under 5 years old. Diagnosis was entertained and established prior to autopsy in 1 of the 3 patients, i.e., the surviving 72-hour-old newborn infant. It is of note, however, that the other 2 patients had rather serious associated conditions. We have no recent follow-up available on our patient; however, at the age of 1 year the patient was doing well and had had no further difficulty. VAN D. C H U N N , JR., M.D.
Cryptococcus meningitis treated ~vitb ampbotericin B To the Editor: Since publication of our paper (Emanuel, Ching, Lieberman, and Goldin: "Cryptococcus meningitis in a child successfully treated with amphotericin B, with a review of the pediatric literature") in the October issue of volume 59 of the JOURNAL we have discovered an omission in the review of the literature, tIooft, Pintelon, and Callens ("Mdningite 5 cryptococcus," Acta
paediat. Belg. 4: 152, 1955) describe the case of a boy 13 years of age who was treated for 9 months with streptomycin, INH, and PAS for tuberculosis, after a positive skin test for tuberculosis. After the culture of cryptococcus from the spinal fluid, the patient was treated with elkosine. He continues to be well and normal. B. E1ViANUEL9 M,D.
Correspondence
demonstration and diagnosis and "third priority" in respect to survival. It may be noted that the infant in our case was less than 72 hours old at the time of the operation. Since a complete review of the literature was not undertaken, we cannot be sure that some other cases of this rare condition in the newborn, with diagnosis and survival, have not been recorded. The importance of early diagnosis and therapy cannot be overemphasized. Three of the 9 patients alluded to in the paper by Drs.
July 1962
Dorsey, Hohf, and Lynn were under 5 years old. Diagnosis was entertained and established prior to autopsy in 1 of the 3 patients, i.e., the surviving 72-hour-old newborn infant. It is of note, however, that the other 2 patients had rather serious associated conditions. We have no recent follow-up available on our patient; however, at the age of 1 year the patient was doing well and had had no further difficulty. VAN D. C H U N N , JR., M.D.
Cryptococcus meningitis treated ~vitb ampbotericin B To the Editor: Since publication of our paper (Emanuel, Ching, Lieberman, and Goldin: "Cryptococcus meningitis in a child successfully treated with amphotericin B, with a review of the pediatric literature") in the October issue of volume 59 of the JOURNAL we have discovered an omission in the review of the literature, tIooft, Pintelon, and Callens ("Mdningite 5 cryptococcus," Acta
paediat. Belg. 4: 152, 1955) describe the case of a boy 13 years of age who was treated for 9 months with streptomycin, INH, and PAS for tuberculosis, after a positive skin test for tuberculosis. After the culture of cryptococcus from the spinal fluid, the patient was treated with elkosine. He continues to be well and normal. B. E1ViANUEL9 M,D.