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Curling of Curling's ulcer
May 1998
COST ANALYSIS OF FAP SCREENING STRATEGIES
8. Powell SM, Petersen GM, Krush AJ, Booker SV, Jen J, Giardiello FM, Hamilton SR, Vogelstein B, Kinzler KW. Molecular diagnosis of familial adenomatous polyposis. N Engl J Med 1993;329:1982– 1987. 9. Petersen GM, Slack J, Nakamura Y. Screening guidelines and premorbid diagnosis of familial adenomatous polyposis using linkage. Gastroenterology 1990;100:1658–1664. 10. Petersen GM, Brensinger JD. Genetic testing and counseling of familial adenomatous polyposis. Oncology 1996;10:89–94. 11. Petersen GM, Boyd PA. Gene tests and counseling for colorectal cancer risk: lessons from familial polyposis. Monogr Natl Cancer Inst 1995;17:67–71. 12. Brown ML, Kessler LG. Use of gene tests to detect hereditary predisposition to cancer: what do we know about cost-effectiveness? Int J Cancer 1996;69:55–57. 13. Noorani HZ, Kahn HN, Gallie BL, Detsky AS. Cost comparison of molecular versus conventional screening of relatives at risk for retinoblastoma. Am J Hum Genet 1996;59:301–307. 14. DATA version 3.0.12 user’s manual. Boston: TreeAge software, 1997. 15. Press SJ. Bayesian statistics. Principles, models, and application. New York: Wiley, 1989:23–33. 16. Directory of services. LabCorp molecular biology & pathology. Research Triangle Park, NC: Laboratory Corporation of America.
17.
18.
19. 20.
901
[price information available only by telephone from Laboratory Corporation of America, Center for Molecular Biology and Pathology]. Weinstein MC, Fineberg HV, Elstein AS, Frazier HS, Neuhauser D, Neutra RR, McNeil BJ. Clinical decision analysis. Philadelphia: Saunders, 1980:248–250. Weinstein MC, Siegel JE, Gold MR, Kamlet MS, Russell LB. Recommendations of the panel of cost-effectiveness in health and medicine. JAMA 1996;276:1253–1258. Dukes CE. Cancer of the rectum. An analysis of 1000 cases. J Pathol Bacteriol 1940:50:527–539. Astler VB, Coller FA. The prognostic significance of direct extension of carcinoma of the colon and rectum. Ann Surg 1954;139: 846–851.
Received August 5, 1997. Accepted January 20, 1998. Address requests for reprints to: David M. Cromwell, M.D., Johns Hopkins School of Medicine, 1830 East Monument Street, #8061, Baltimore, Maryland 21287. Fax: (410) 955-0825. Supported in part by The Clayton Fund and National Institutes of Health grants CA 53801, CA 62924, and CA 95-21. The authors thank Harold P. Lehmann, M.D., Ph.D., for his advice in the construction of the decision analytic model.
Curling of Curling’s ulcer
Thomas Blizard Curling (1811–1888) was born in London. At age 21, though lacking a medical degree, he was appointed assistant surgeon at the London Hospital, probably through the influence of his uncle Sir William Blizard. In 1842, he presented to the Royal Medico-Chirugical Society his well documented paper describing duodenal ulceration in association with severe burns. In 1850 he correlated clinical features with absence of thyroid function, preceding by nearly a quarter-century Sir William Gull’s description of what became known as myxedema. Curling was a strong advocate of liberal education as essential to the study of medicine. Before age 60 he retired to Brighton; he died in Cannes, France. —contributed by WILLIAM S. HAUBRICH, M.D. Scripps Clinic and Research Foundation, La Jolla, California
COST ANALYSIS OF FAP SCREENING STRATEGIES
8. Powell SM, Petersen GM, Krush AJ, Booker SV, Jen J, Giardiello FM, Hamilton SR, Vogelstein B, Kinzler KW. Molecular diagnosis of familial adenomatous polyposis. N Engl J Med 1993;329:1982– 1987. 9. Petersen GM, Slack J, Nakamura Y. Screening guidelines and premorbid diagnosis of familial adenomatous polyposis using linkage. Gastroenterology 1990;100:1658–1664. 10. Petersen GM, Brensinger JD. Genetic testing and counseling of familial adenomatous polyposis. Oncology 1996;10:89–94. 11. Petersen GM, Boyd PA. Gene tests and counseling for colorectal cancer risk: lessons from familial polyposis. Monogr Natl Cancer Inst 1995;17:67–71. 12. Brown ML, Kessler LG. Use of gene tests to detect hereditary predisposition to cancer: what do we know about cost-effectiveness? Int J Cancer 1996;69:55–57. 13. Noorani HZ, Kahn HN, Gallie BL, Detsky AS. Cost comparison of molecular versus conventional screening of relatives at risk for retinoblastoma. Am J Hum Genet 1996;59:301–307. 14. DATA version 3.0.12 user’s manual. Boston: TreeAge software, 1997. 15. Press SJ. Bayesian statistics. Principles, models, and application. New York: Wiley, 1989:23–33. 16. Directory of services. LabCorp molecular biology & pathology. Research Triangle Park, NC: Laboratory Corporation of America.
17.
18.
19. 20.
901
[price information available only by telephone from Laboratory Corporation of America, Center for Molecular Biology and Pathology]. Weinstein MC, Fineberg HV, Elstein AS, Frazier HS, Neuhauser D, Neutra RR, McNeil BJ. Clinical decision analysis. Philadelphia: Saunders, 1980:248–250. Weinstein MC, Siegel JE, Gold MR, Kamlet MS, Russell LB. Recommendations of the panel of cost-effectiveness in health and medicine. JAMA 1996;276:1253–1258. Dukes CE. Cancer of the rectum. An analysis of 1000 cases. J Pathol Bacteriol 1940:50:527–539. Astler VB, Coller FA. The prognostic significance of direct extension of carcinoma of the colon and rectum. Ann Surg 1954;139: 846–851.
Received August 5, 1997. Accepted January 20, 1998. Address requests for reprints to: David M. Cromwell, M.D., Johns Hopkins School of Medicine, 1830 East Monument Street, #8061, Baltimore, Maryland 21287. Fax: (410) 955-0825. Supported in part by The Clayton Fund and National Institutes of Health grants CA 53801, CA 62924, and CA 95-21. The authors thank Harold P. Lehmann, M.D., Ph.D., for his advice in the construction of the decision analytic model.
Curling of Curling’s ulcer
Thomas Blizard Curling (1811–1888) was born in London. At age 21, though lacking a medical degree, he was appointed assistant surgeon at the London Hospital, probably through the influence of his uncle Sir William Blizard. In 1842, he presented to the Royal Medico-Chirugical Society his well documented paper describing duodenal ulceration in association with severe burns. In 1850 he correlated clinical features with absence of thyroid function, preceding by nearly a quarter-century Sir William Gull’s description of what became known as myxedema. Curling was a strong advocate of liberal education as essential to the study of medicine. Before age 60 he retired to Brighton; he died in Cannes, France. —contributed by WILLIAM S. HAUBRICH, M.D. Scripps Clinic and Research Foundation, La Jolla, California