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Cytokines regulating the allergic responses
Gen. Pharmac. Vol. 21, No. 6, pp. 969-971, 1990 Printed in Great Britain
0306-3623/90 $3.00 + 0.00 Pergamon Press plc
BOOK REVIEWS Reviews of Physiology, Biochemistry and Pharmacology. VoI. 114. Special Issue on Ionic Channels. 264 pp. 1990. Springer Verlag, Berlin. $79.50. There are three reviews in this issue. (1) Molecular properties of calcium channels; (2) properties and regulation of calcium channels in muscle cells; (3) pharmacological modulation of voltage dependent calcium channels in intact cells. They provide an excellent illustrated up to date account of these important membrane channels. Percutaneons Absorption: Mechanisms, Methodology and Drug Delivery. 2nd Edtr---Edited by R. L. Bronaugh and H. L. Maibach. 664 pp. 1989. Humana Press, Clifton, NJ. $125 (USA and Canada), $150 elsewhere. Drugs given via the skin have many advantages; the total dose given can be smaller than that given by other methods: the drugs can be given continuously at a finite rate: it has a high patient acceptability; the method of application of a common drug can be patented. The new edition of this book brings the information up to date and in the 37 chapters considers the fundamental problems of drug absorption via the skin and the methods that are being used to obtain reliable delivery of drugs. Maternal-fetal Toxicology: a Clinician's Guide---Edited by G. Koren. 436 pp. 1990. Marcel Dekker, New York. $125 (USA & Canada), $150 elsewhere. Approximately one fetus is aborted for every child born in western countries; 40-90% of pregnant women consume one or more medications during pregnancy; many women take medication before they know that they are pregnant. This book is designed to give more information on the risks of drug consumption during pregnancy. The main sections are: drugs in pregnancy (includes a list of 102 drugs toxic to the fetus with alternative safer medication); poisoning and radiation in pregnancy; genetic and obstetric considerations; organizations and operation of teratogenic information services. Chronopharmacology: Cellular and Biochemical Interactions --Edited by B. Lemmer. 720 pp. 1989. Marcel Dekker, New York. $150 (USA & Canada), $180 elsewhere. A given dose of a drug can have a greater or lesser effect depending on the time of day when it is administered. This volume reviews the general aspects of chronopharmacokinetics with regard to absorption, distribution, metabolism, and elimination; surveys the temperal effects of drugs given for the treatment of asthma and allergic diseases; cancer; cardiovascular drugs; anti-inflammatory, analgesics and anaesthetics; endocrinology; nephrotoxicity of heavy metals and antibiotics; and embryotoxicity.
chemical kinetics and drug stability; preformulation; topical absorption; disperse systems; tablet dosage forms; speciality tablets and capsules (sublingual, buccal and transmucosal, implants): gelatin capsules; parenteral products; opthalmic drugs; aerosols; sustained and controlled release; site specific delivery; packaging of dosage forms; appraisal of quality and performance; optimization techniques; food and drug laws. Adrenergic System and Ventrtcular Arrhythmins in Myocardial Infarction--Edited by J. Brachmann and A. Schomig. 363 pp. 1989. Springer Verlag, Berlin. DM 126. Basic electrophysiological studies on the responses of cardiac muscle to catecholamines, and clinical studies on acute and chronic myocardial ischaemia are brought together in this book. The main chapters are on the release and uptake of catecholamines in ischaemia; regulation of receptors; the adrenergic contribution to ventricular arrhythmias; ischaemic malignant arrhythmias; the membrane currents (Ca, Na, K, pH) in ventricular arrhythmias; mechanisms of arrhythmias, ventricular muscle responses to beta blockers, sudden cardiac death in man. The Neuropeptide Cholecystokinin (CCK)---Edited by J. Hughes, G. Dockray and G. Woodruff. 252 pp. 1989. Wiley, Chichester. $89.95. The topics covered in this book are: CCK like immunoreactivity in neurons and non-neurons; CCK immunoreactivity in Huntington's chorea; a Drosophila homolog to the CCK/gastrin peptide family; developmental changes of CCK mRNA in developing rat brain; prepro-CCK; release of CCK from brain and spinal cord; non-peptide CCK antagonists; CCK binding site heterogeneity; CCK and antipsychotic drugs; CCK and enhanced dopamine release; L-364,718 and food intake; integrative functions of CCK. Cytokines Regulating the Allergic Responses~Edited by C. Sorg. 105 pp. 1989. Karger, Basel. S. Fr 95, $63.50. The chapters review the role in allergy of: IgE, IL-4 and FCe receptor II, cytokines and anti-lgE antibodies, PAF/cytokine interactions in inflammation, IL-3 and IL-4 and mast cell development in mice, regulation of basophil and mast cell activation by cytokines. New Drugs In Oocology--Edited by W. Queisser and H. H. Fiebig. 302 pp. 1989. Karger, Basel. S. Fr. 79, $52.75. This volume contains a series of papers on the use of different drugs to treat cancers. These include 5-fluorouracil, 5 Aza-2-deoxycytidine, cabergoline, droloxifene, zindoxifene, 4-hydroxy-androstenedione, anthracylines (pirarubicin, idarubicin epirubicin), nitrosoureas, metal complexes, ether lipids, immune modulators and interferons.
Modem Pharmaeeutics. 2nd Edn--Edited by G. S. Banker and C. T. Rhodes. 888 pp. 1990. Marcel Dekker, New York. $125 (USA and Canada), $150 elsewhere.
Liver Cell Carcinoma--Edited by P. Bannasch, D. Keppler and G. Weber. 525 pp. 1989. Kluwer, Dordecht. D.FI 289, SI21.50.
The aim of this book is to provide information on the ways that the quality of a drug dosage can be assessed, and the role that pharmacokinetics has on the efficacy of a drug. The main sections are: drug absorption; pharmacokinetics; drug availability; route of administration; drug distribution;
Three main risk factors for liver cancer are hepatitis B virus (HBV), aflatoxins and alcohol abuse. It is estimated that the lag between infection with HBV and the appearance of hepatocellular carcinoma takes 30-50 years. Animal models 969
0306-3623/90 $3.00 + 0.00 Pergamon Press plc
BOOK REVIEWS Reviews of Physiology, Biochemistry and Pharmacology. VoI. 114. Special Issue on Ionic Channels. 264 pp. 1990. Springer Verlag, Berlin. $79.50. There are three reviews in this issue. (1) Molecular properties of calcium channels; (2) properties and regulation of calcium channels in muscle cells; (3) pharmacological modulation of voltage dependent calcium channels in intact cells. They provide an excellent illustrated up to date account of these important membrane channels. Percutaneons Absorption: Mechanisms, Methodology and Drug Delivery. 2nd Edtr---Edited by R. L. Bronaugh and H. L. Maibach. 664 pp. 1989. Humana Press, Clifton, NJ. $125 (USA and Canada), $150 elsewhere. Drugs given via the skin have many advantages; the total dose given can be smaller than that given by other methods: the drugs can be given continuously at a finite rate: it has a high patient acceptability; the method of application of a common drug can be patented. The new edition of this book brings the information up to date and in the 37 chapters considers the fundamental problems of drug absorption via the skin and the methods that are being used to obtain reliable delivery of drugs. Maternal-fetal Toxicology: a Clinician's Guide---Edited by G. Koren. 436 pp. 1990. Marcel Dekker, New York. $125 (USA & Canada), $150 elsewhere. Approximately one fetus is aborted for every child born in western countries; 40-90% of pregnant women consume one or more medications during pregnancy; many women take medication before they know that they are pregnant. This book is designed to give more information on the risks of drug consumption during pregnancy. The main sections are: drugs in pregnancy (includes a list of 102 drugs toxic to the fetus with alternative safer medication); poisoning and radiation in pregnancy; genetic and obstetric considerations; organizations and operation of teratogenic information services. Chronopharmacology: Cellular and Biochemical Interactions --Edited by B. Lemmer. 720 pp. 1989. Marcel Dekker, New York. $150 (USA & Canada), $180 elsewhere. A given dose of a drug can have a greater or lesser effect depending on the time of day when it is administered. This volume reviews the general aspects of chronopharmacokinetics with regard to absorption, distribution, metabolism, and elimination; surveys the temperal effects of drugs given for the treatment of asthma and allergic diseases; cancer; cardiovascular drugs; anti-inflammatory, analgesics and anaesthetics; endocrinology; nephrotoxicity of heavy metals and antibiotics; and embryotoxicity.
chemical kinetics and drug stability; preformulation; topical absorption; disperse systems; tablet dosage forms; speciality tablets and capsules (sublingual, buccal and transmucosal, implants): gelatin capsules; parenteral products; opthalmic drugs; aerosols; sustained and controlled release; site specific delivery; packaging of dosage forms; appraisal of quality and performance; optimization techniques; food and drug laws. Adrenergic System and Ventrtcular Arrhythmins in Myocardial Infarction--Edited by J. Brachmann and A. Schomig. 363 pp. 1989. Springer Verlag, Berlin. DM 126. Basic electrophysiological studies on the responses of cardiac muscle to catecholamines, and clinical studies on acute and chronic myocardial ischaemia are brought together in this book. The main chapters are on the release and uptake of catecholamines in ischaemia; regulation of receptors; the adrenergic contribution to ventricular arrhythmias; ischaemic malignant arrhythmias; the membrane currents (Ca, Na, K, pH) in ventricular arrhythmias; mechanisms of arrhythmias, ventricular muscle responses to beta blockers, sudden cardiac death in man. The Neuropeptide Cholecystokinin (CCK)---Edited by J. Hughes, G. Dockray and G. Woodruff. 252 pp. 1989. Wiley, Chichester. $89.95. The topics covered in this book are: CCK like immunoreactivity in neurons and non-neurons; CCK immunoreactivity in Huntington's chorea; a Drosophila homolog to the CCK/gastrin peptide family; developmental changes of CCK mRNA in developing rat brain; prepro-CCK; release of CCK from brain and spinal cord; non-peptide CCK antagonists; CCK binding site heterogeneity; CCK and antipsychotic drugs; CCK and enhanced dopamine release; L-364,718 and food intake; integrative functions of CCK. Cytokines Regulating the Allergic Responses~Edited by C. Sorg. 105 pp. 1989. Karger, Basel. S. Fr 95, $63.50. The chapters review the role in allergy of: IgE, IL-4 and FCe receptor II, cytokines and anti-lgE antibodies, PAF/cytokine interactions in inflammation, IL-3 and IL-4 and mast cell development in mice, regulation of basophil and mast cell activation by cytokines. New Drugs In Oocology--Edited by W. Queisser and H. H. Fiebig. 302 pp. 1989. Karger, Basel. S. Fr. 79, $52.75. This volume contains a series of papers on the use of different drugs to treat cancers. These include 5-fluorouracil, 5 Aza-2-deoxycytidine, cabergoline, droloxifene, zindoxifene, 4-hydroxy-androstenedione, anthracylines (pirarubicin, idarubicin epirubicin), nitrosoureas, metal complexes, ether lipids, immune modulators and interferons.
Modem Pharmaeeutics. 2nd Edn--Edited by G. S. Banker and C. T. Rhodes. 888 pp. 1990. Marcel Dekker, New York. $125 (USA and Canada), $150 elsewhere.
Liver Cell Carcinoma--Edited by P. Bannasch, D. Keppler and G. Weber. 525 pp. 1989. Kluwer, Dordecht. D.FI 289, SI21.50.
The aim of this book is to provide information on the ways that the quality of a drug dosage can be assessed, and the role that pharmacokinetics has on the efficacy of a drug. The main sections are: drug absorption; pharmacokinetics; drug availability; route of administration; drug distribution;
Three main risk factors for liver cancer are hepatitis B virus (HBV), aflatoxins and alcohol abuse. It is estimated that the lag between infection with HBV and the appearance of hepatocellular carcinoma takes 30-50 years. Animal models 969