Denicotinized Tobacco. Several processes may be used in the preparation of denicotinized tobacco. Nicotine may be removed by the use of suitable solvents; or the tobacco may be subjected to a resweating either by treatment with superheated steam or by heating in a vacuum chamber. E . M . BAILEY, O. L. NOLAN, and W. T. MATHIS (Conn. Agric. Exp. Station Bull. 295,338-351, 1928) have analyzed 17 samples of denicotinized tobacco as found on the market in cigars, cigarettes, and smoking tobacco. For comparison they also analyzed 18 samples of ordinary tobacco as found on the market, and collected from the literature 4o additional analyses of ordinary tobacco as found in cigars, cigarettes, and smoking and chewing tobacco. The total nicotine content, calculated on the moisture-free basis, ranged between o.47 and 3.63 with an average of 1.96 per cent. in the 58 analyses of ordinary tobacco, and between o.74 and 2.73 with an average of 1.41 per cent. in the 17 analyses of denicotinized tobacco. When tobaccos of corresponding leaf types were compared, the denicotinized products, as a rule, contained but little less nicotine than the ordinary products. While considerable reductions in nicotine content were indicated in certain instances, yet it was not difficult to find brands of ordinary tobacco with a nicotine content not greatly in excess of that present in the most thoroughly processed of the denicotinized products. Nicotine is an important, if not the chief, factor in the production of the satisfying effects derived from smoking. Use of denicotinized products may lead to increased indulgence; and the actual nicotine intake may equal or exceed that when ordinary tobacco is used. None of the denicotinized tobaccos analyzed were sufficiently low in nicotine content to warrant unrestricted indulgence by persons who suffer ill effects from this alkaloid. Free nicotine occurs in tobacco, and is due, apparently, to the dissociation of the nicotine salts of organic acids. The harsh and irritating effects on smoking may be due to free nicotine. Denicotinized tobacco did not differ markedly from ordinary tobacco with respect to the free nicotine content. The distribution of the nitrogen as nitrate nitrogen and as ammoniacal nitrogen was practically identical in the two classes of tobacco. J. S. H.