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Depletion of iron-containing enzymes in iron deficiency anemia
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Letters to the Editor
The Journal o[ Pediatrics January 1973
Editorial correondence
"Editorial Correspondence" or letters to the Editor relative to articles published in the JOUR?,'AL or to topics of current interest are subject to critical review and to current editorial policy in respect to publication in part or in full,
Endotracbeal tube position in infants
Depletion of iron-containing enzymes in iron deficiency anemia
To the Editor:
To the Editor:
Drs. Kuhns and Poznanski 1 are to be commended for reminding both pediatricians and anesthesiologists that accidental endobronchial intubation can easily pass undetected. They suggest that centimeter markings be placed on all endotracheal tubes to aid correct positioning. We investigated this possibility in 1969 and came to the conclusion that circumferential rings would be readily visible3 For red rubber tubes this is technically feasible, although the cost would be doubled. However, for polyvinyl chloride tubes, as are used in neonatal resuscitation, manufacturers (Portex Ltd., England) indicated rings would be difficult to print on. In any case there appears to have been no demand here, although some adult endotracheal tubes of German manufacture are available with distance markers. A polyvinyl chloride tube with a shoulder to limit tracheal length s continues to receive widespread acceptance.
In the June, 1972, issue of the JOURNAl., Dr. Fnerth 1 stated that the depletion of iron-containing enzymes in iron deficiency anemia has only been demonstrated in animal experiments. I would like to inform the author that decreased activity of one of the iron-containing enzymes (catalase) in children with iron deficiency anemia was demonstrated in 1964, 2 and later confirmed by Sagone and Balcerzak a and Macdougall. 4
W. Lindsay, M.B., F.F.A., R.C.S. Queen Mary's Hospital [or Children Carshalton, Surrey, England REFERENCES 1. Kuhns, L. R., and Poznanski, A. K.: Endotracheal tube position in the infant, J. PEDIATR. 78: 991, 1971. 2. Lindsay, W. A.: Distance marker rings on endotracheal tubes, Lancet I: 220, 1970. 3. Tunstall, M. E., and Hodges, R. J.: A sterile disposable neonatal tracheal tube, Lancet 1: 146, 1961.
Sinasi Ozsoylu, M.D. Department o[ Pediatrics University o[ Maryland School of Medicine 22 S. Greene St. Baltimore, Md. 21201 REFERENCES 1. Fuerth, J. H.: Iron supplementation of the diet in full-term infants: A controlled study, J. P~DIAT. 80Z 974, 1972. 2. Ozsoylu, S.: Decreased activity of the iron containing enzyme, catalase, in human irondeficiency anemia, Turk. J. Pediatr. 6: 200, 1964. 3. Sagone, A. L., Jr., and Balcerzak, S. P.: Activity of iron containing enzymes in erythroeytes and granulocytes in thalassemla and iron deficiency, Am. J. Med. Scl. 259: 350, 1970. 4. Macdougall, L. G.: Red cell metabolism in iron deficiency anemia. 111. The relationship between glutathione, peroxidase, catalase, serum vitamin E, and susceptibility of iron-deficient red cells to oxidative hemolysis, J. PEmATR. 80: 775, 1972.
Letters to the Editor
The Journal o[ Pediatrics January 1973
Editorial correondence
"Editorial Correspondence" or letters to the Editor relative to articles published in the JOUR?,'AL or to topics of current interest are subject to critical review and to current editorial policy in respect to publication in part or in full,
Endotracbeal tube position in infants
Depletion of iron-containing enzymes in iron deficiency anemia
To the Editor:
To the Editor:
Drs. Kuhns and Poznanski 1 are to be commended for reminding both pediatricians and anesthesiologists that accidental endobronchial intubation can easily pass undetected. They suggest that centimeter markings be placed on all endotracheal tubes to aid correct positioning. We investigated this possibility in 1969 and came to the conclusion that circumferential rings would be readily visible3 For red rubber tubes this is technically feasible, although the cost would be doubled. However, for polyvinyl chloride tubes, as are used in neonatal resuscitation, manufacturers (Portex Ltd., England) indicated rings would be difficult to print on. In any case there appears to have been no demand here, although some adult endotracheal tubes of German manufacture are available with distance markers. A polyvinyl chloride tube with a shoulder to limit tracheal length s continues to receive widespread acceptance.
In the June, 1972, issue of the JOURNAl., Dr. Fnerth 1 stated that the depletion of iron-containing enzymes in iron deficiency anemia has only been demonstrated in animal experiments. I would like to inform the author that decreased activity of one of the iron-containing enzymes (catalase) in children with iron deficiency anemia was demonstrated in 1964, 2 and later confirmed by Sagone and Balcerzak a and Macdougall. 4
W. Lindsay, M.B., F.F.A., R.C.S. Queen Mary's Hospital [or Children Carshalton, Surrey, England REFERENCES 1. Kuhns, L. R., and Poznanski, A. K.: Endotracheal tube position in the infant, J. PEDIATR. 78: 991, 1971. 2. Lindsay, W. A.: Distance marker rings on endotracheal tubes, Lancet I: 220, 1970. 3. Tunstall, M. E., and Hodges, R. J.: A sterile disposable neonatal tracheal tube, Lancet 1: 146, 1961.
Sinasi Ozsoylu, M.D. Department o[ Pediatrics University o[ Maryland School of Medicine 22 S. Greene St. Baltimore, Md. 21201 REFERENCES 1. Fuerth, J. H.: Iron supplementation of the diet in full-term infants: A controlled study, J. P~DIAT. 80Z 974, 1972. 2. Ozsoylu, S.: Decreased activity of the iron containing enzyme, catalase, in human irondeficiency anemia, Turk. J. Pediatr. 6: 200, 1964. 3. Sagone, A. L., Jr., and Balcerzak, S. P.: Activity of iron containing enzymes in erythroeytes and granulocytes in thalassemla and iron deficiency, Am. J. Med. Scl. 259: 350, 1970. 4. Macdougall, L. G.: Red cell metabolism in iron deficiency anemia. 111. The relationship between glutathione, peroxidase, catalase, serum vitamin E, and susceptibility of iron-deficient red cells to oxidative hemolysis, J. PEmATR. 80: 775, 1972.