- Email: [email protected]
Description of associated chronic comorbidities in children with type 2 diabetes mellitus and impaired glucose tolerance
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Abstracts/Appetite 89 (2015) 301–330
Parents’ concerns and family environment are associated with overweight children’s physical activity levels. The ACORDA project M.J. LAGOA a,b, G. SILVA a, J. MOTA a, L. AIRES a,b. a Research Centre in Physical Activity, Health and Leisure (CIAFEL), Faculty of Sports – University of Porto, Portugal, b University Institute of Maia (ISMAI), Portugal. [email protected] Parents take most decisions related to children’s lifestyles, such as food choices and time devoted to physical activity (PA). Therefore, the understanding of parental influence in children’s lifestyles might be necessary for preventing childhood obesity and for improving children’s PA. Thus, this study aimed to analyse the associations between parents’ concerns, family environment, and children’s PA. Participants were 56 children (age between 6 and 11) with overweight (28.4%) and obesity (27.5%) and their respective parents. The sum family screen gadgets (FSG), parental encouragement for children’s PA (PECPA) and parental accompaniment for children’s sports (PACS) were assessed by questionnaire. Children’s sedentary (SPA) and light PA (LPA) were assessed by accelerometers. The relationships between variables were analysed by linear regression and the significance level was set at 5%. Linear regression showed that PECPA was associated with SPA (R2 = 0.13, F = 2.68, p < 0.03, β = 437.17), independently of PACS. FSG was associated with LPA (R2 = 0.16, F = 4.33, p < 0.05, β = 451.14). The final model shows that parents can contribute to the decrease of sedentary activities of their children, through the incentive to the practice of PA. The family environment, through the FSG, can also contribute to the increase of light activities. Therefore, parents and family environment can play an important role in their children’s PA levels. Supported by FCT – PEst-OE/SAU/UI0617/2014 FEDER funds through the Operational Competitiveness Programme-COMPETE. http://dx.doi.org/10.1016/j.appet.2014.12.039
Topic 3: Metabolic Comorbidities and Obesity Treatment Description of associated chronic comorbidities in children with type 2 diabetes mellitus and impaired glucose tolerance A. MIKILPA-MIKGELBA a,b, I. DZIVITE-KRISANE a,b, J. GAILITE a,b. a Riga Stradin’s University, Latvia, b Children’s Clinical University Hospital, Latvia. [email protected] It is very important to examine children and adolescents with type 2 diabetes mellitus (DM) and impaired glucose tolerance (IGT) for associated chronic comorbidities such as dyslipidemia, hypertension and fatty liver disease (FLD) etc. It would help to distinguish increased-risk group for cardiovascular diseases and poor life quality – associated with continuous medical care. The management of this group should rely on more intense life-style correction – a healthy and balanced diet and increased physical activity. This study aimed to analyze and compare children suffering from type 2 DM with those having IGT in terms of chronic comorbidities such as dyslipidemia, hypertension and FLD. We performed a retrospective study, including children with diagnosed type 2 DM or IGT. Data were collected
from department of endocrinology and children’s diabetes care unit in the Children’s Clinical University Hospital (Riga, Latvia) during the period from 2002 to 2013. Data including hypertension, FLD (found in ultrasound) and lipid profile were analyzed. Medical data of 54 patients were analyzed. Forty-three percent (n = 23) had type 2 DM and 57% (n = 31) had IGT. Hypertension was detected in 65% (n = 15) for type 2 DM group and 55% (n = 17) for IGT group (p = 0.28). FLD was observed in 22% (n = 5) for type 2 DM group and 19% (n = 6) for IGT group (p = 0.83). Dyslipidemia was found in 52% (n = 12) for type 2 DM group and 16% (n = 5) for IGT group (p < 0.05). This study shows that children suffering from type 2 DM more frequently have dyslipidemia compared with those who have IGT. There were no significant differences found between these groups in terms of hypertension and FLD. http://dx.doi.org/10.1016/j.appet.2014.12.040
Glucose homeostasis and insulin resistance in adolescents. Prevalence, gender differences and predictors H. ZAMRAZILOVÁ a, I. ALDHOON-HAINEROVÁ a,b, L. DUŠÁTKOVÁ a, ˇ KOVÁ a, M. KUNEŠOVÁ a, V. HAINER a. a Obesity Management B. SEDLÁC Center, Institute of Endocrinology, Prague, Czech Republic, b Department of Pediatrics, Third Faculty of Medicine, Charles University, Prague, Czech Republic. [email protected] Adolescence, due to transient pubertal insulin resistance (IR), is associated with a higher risk for disturbances of glucose metabolism. The aim of this study was to investigate: 1) prevalence of IR, impaired fasting glucose (IFG) and type 2 diabetes (T2DM), 2) gender specific homeostasis model assessment of insulin resistance (HOMAIR) thresholds associated with increased cardiometabolic risks and 3) predictors of HOMA-IR. The cohort included 1518 adolescents of general population, 615 normal weight, 230 overweight and 683 obese adolescents aged 13.0–17.9 years. Risky HOMA-IR thresholds based on components of metabolic syndrome were investigated. HOMA-IR prediction was calculated taking into account age, blood pressure, multiple anthropometric, biochemical, psychobehavioural and infectious parameters. In the general population, the prevalence of IFG and T2DM was 7.0% and <0.5%, respectively. Boys regardless of weight presented significantly higher levels of blood glucose and higher prevalence of IFG than girls. HOMA-IR thresholds of 3.6 for girls and 4.4 for boys were associated with increased cardiometabolic risks. For both genders, the model of HOMA-IR prediction was composed of age, body mass index, ratio of free triiodthyronine to free thyroxine, levels of triglycerides, gammaglutamyltransferase activity and sex hormone-binding globulin and additionally of testosterone for boys. T2DM in adolescents, including those who were obese, was rarely diagnosed. Obese adolescent boys were at greater risk for IR and IFG than obese girls. In adolescence, thresholds of HOMA-IR in contrast to predictors were found gender specific. Research was supported by grants IGA MZCR NT/ 13792-4 and MH CZ-DRO (Institute of Endocrinology – EÚ, 00023761). http://dx.doi.org/10.1016/j.appet.2014.12.041
Abstracts/Appetite 89 (2015) 301–330
Parents’ concerns and family environment are associated with overweight children’s physical activity levels. The ACORDA project M.J. LAGOA a,b, G. SILVA a, J. MOTA a, L. AIRES a,b. a Research Centre in Physical Activity, Health and Leisure (CIAFEL), Faculty of Sports – University of Porto, Portugal, b University Institute of Maia (ISMAI), Portugal. [email protected] Parents take most decisions related to children’s lifestyles, such as food choices and time devoted to physical activity (PA). Therefore, the understanding of parental influence in children’s lifestyles might be necessary for preventing childhood obesity and for improving children’s PA. Thus, this study aimed to analyse the associations between parents’ concerns, family environment, and children’s PA. Participants were 56 children (age between 6 and 11) with overweight (28.4%) and obesity (27.5%) and their respective parents. The sum family screen gadgets (FSG), parental encouragement for children’s PA (PECPA) and parental accompaniment for children’s sports (PACS) were assessed by questionnaire. Children’s sedentary (SPA) and light PA (LPA) were assessed by accelerometers. The relationships between variables were analysed by linear regression and the significance level was set at 5%. Linear regression showed that PECPA was associated with SPA (R2 = 0.13, F = 2.68, p < 0.03, β = 437.17), independently of PACS. FSG was associated with LPA (R2 = 0.16, F = 4.33, p < 0.05, β = 451.14). The final model shows that parents can contribute to the decrease of sedentary activities of their children, through the incentive to the practice of PA. The family environment, through the FSG, can also contribute to the increase of light activities. Therefore, parents and family environment can play an important role in their children’s PA levels. Supported by FCT – PEst-OE/SAU/UI0617/2014 FEDER funds through the Operational Competitiveness Programme-COMPETE. http://dx.doi.org/10.1016/j.appet.2014.12.039
Topic 3: Metabolic Comorbidities and Obesity Treatment Description of associated chronic comorbidities in children with type 2 diabetes mellitus and impaired glucose tolerance A. MIKILPA-MIKGELBA a,b, I. DZIVITE-KRISANE a,b, J. GAILITE a,b. a Riga Stradin’s University, Latvia, b Children’s Clinical University Hospital, Latvia. [email protected] It is very important to examine children and adolescents with type 2 diabetes mellitus (DM) and impaired glucose tolerance (IGT) for associated chronic comorbidities such as dyslipidemia, hypertension and fatty liver disease (FLD) etc. It would help to distinguish increased-risk group for cardiovascular diseases and poor life quality – associated with continuous medical care. The management of this group should rely on more intense life-style correction – a healthy and balanced diet and increased physical activity. This study aimed to analyze and compare children suffering from type 2 DM with those having IGT in terms of chronic comorbidities such as dyslipidemia, hypertension and FLD. We performed a retrospective study, including children with diagnosed type 2 DM or IGT. Data were collected
from department of endocrinology and children’s diabetes care unit in the Children’s Clinical University Hospital (Riga, Latvia) during the period from 2002 to 2013. Data including hypertension, FLD (found in ultrasound) and lipid profile were analyzed. Medical data of 54 patients were analyzed. Forty-three percent (n = 23) had type 2 DM and 57% (n = 31) had IGT. Hypertension was detected in 65% (n = 15) for type 2 DM group and 55% (n = 17) for IGT group (p = 0.28). FLD was observed in 22% (n = 5) for type 2 DM group and 19% (n = 6) for IGT group (p = 0.83). Dyslipidemia was found in 52% (n = 12) for type 2 DM group and 16% (n = 5) for IGT group (p < 0.05). This study shows that children suffering from type 2 DM more frequently have dyslipidemia compared with those who have IGT. There were no significant differences found between these groups in terms of hypertension and FLD. http://dx.doi.org/10.1016/j.appet.2014.12.040
Glucose homeostasis and insulin resistance in adolescents. Prevalence, gender differences and predictors H. ZAMRAZILOVÁ a, I. ALDHOON-HAINEROVÁ a,b, L. DUŠÁTKOVÁ a, ˇ KOVÁ a, M. KUNEŠOVÁ a, V. HAINER a. a Obesity Management B. SEDLÁC Center, Institute of Endocrinology, Prague, Czech Republic, b Department of Pediatrics, Third Faculty of Medicine, Charles University, Prague, Czech Republic. [email protected] Adolescence, due to transient pubertal insulin resistance (IR), is associated with a higher risk for disturbances of glucose metabolism. The aim of this study was to investigate: 1) prevalence of IR, impaired fasting glucose (IFG) and type 2 diabetes (T2DM), 2) gender specific homeostasis model assessment of insulin resistance (HOMAIR) thresholds associated with increased cardiometabolic risks and 3) predictors of HOMA-IR. The cohort included 1518 adolescents of general population, 615 normal weight, 230 overweight and 683 obese adolescents aged 13.0–17.9 years. Risky HOMA-IR thresholds based on components of metabolic syndrome were investigated. HOMA-IR prediction was calculated taking into account age, blood pressure, multiple anthropometric, biochemical, psychobehavioural and infectious parameters. In the general population, the prevalence of IFG and T2DM was 7.0% and <0.5%, respectively. Boys regardless of weight presented significantly higher levels of blood glucose and higher prevalence of IFG than girls. HOMA-IR thresholds of 3.6 for girls and 4.4 for boys were associated with increased cardiometabolic risks. For both genders, the model of HOMA-IR prediction was composed of age, body mass index, ratio of free triiodthyronine to free thyroxine, levels of triglycerides, gammaglutamyltransferase activity and sex hormone-binding globulin and additionally of testosterone for boys. T2DM in adolescents, including those who were obese, was rarely diagnosed. Obese adolescent boys were at greater risk for IR and IFG than obese girls. In adolescence, thresholds of HOMA-IR in contrast to predictors were found gender specific. Research was supported by grants IGA MZCR NT/ 13792-4 and MH CZ-DRO (Institute of Endocrinology – EÚ, 00023761). http://dx.doi.org/10.1016/j.appet.2014.12.041