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Determination of hyaluronic acid in serum as marker of acute rejection after orthotopic liver transplantation
EFFECT B AM SEW4
S-ADEltOSYVIETHIOWlKE (SW) M( ANY,P"RME TOTAL BILIRUBM 1" CIRRKOTlC PATIEIITS.
MO
RIFMICIII-S" PLF-LIFE
S. entile. II.Per51co.F.S. R"ss0. C. Le h-aric*,C. Bi Padova*.W. Coltorti: Oepartmt of InternalMedicine.First Medical Sc!wol.Universityof Naples, and l EiaResearCh Co., lilan (Italy). Recentwideras indi-atethat W4e is abie to unproveorga;ncanionspharmacok~netics and to re:uce nitot
after before after before aiter 26+ 4 x&l1 36ill at10 5at11 14; 3 11: 3' 16: 4 1273* 19; 5 13: 3' 23C;z6 200;14J 302;29 2177249 34G31 288~29~ 10 parenthesis "umber ;f patient< B-AUC: area w&v &urn total Elirubii, dine c"rve concentration; *p < 0.05; o p < 0.01 vs before by ANOVA. In conclusion, in cirrhotics SAN does i~t seen t3 interfere "7th A? T/2 whereas it Sl9"lftcwtly 5horte"s R-S" T/2 and red"cls R-SV-induced hyperbilirubinaemia. A5 bi:ir"bi" hepatic uptake shares with R-S" a cxn,"n, carrier mediated pathway ltlin Sci 1985;68:675-SO!, the effect of SAMe may be due to the improvement of hepatocyte membrane fluidity. These findings provide s"pport to the "se of SAM8 as an anticholestatic agent in cirrhotics.
AP T/2 ImInI
R-SV T/2 (Inin> B-A”t W"g,di,4hl
before 2% 4
S-ADEltOSYVIETHIOWlKE (SW) M( ANY,P"RME TOTAL BILIRUBM 1" CIRRKOTlC PATIEIITS.
MO
RIFMICIII-S" PLF-LIFE
S. entile. II.Per51co.F.S. R"ss0. C. Le h-aric*,C. Bi Padova*.W. Coltorti: Oepartmt of InternalMedicine.First Medical Sc!wol.Universityof Naples, and l EiaResearCh Co., lilan (Italy). Recentwideras indi-atethat W4e is abie to unproveorga;ncanionspharmacok~netics and to re:uce nitot
after before after before aiter 26+ 4 x&l1 36ill at10 5at11 14; 3 11: 3' 16: 4 1273* 19; 5 13: 3' 23C;z6 200;14J 302;29 2177249 34G31 288~29~ 10 parenthesis "umber ;f patient< B-AUC: area w&v &urn total Elirubii, dine c"rve concentration; *p < 0.05; o p < 0.01 vs before by ANOVA. In conclusion, in cirrhotics SAN does i~t seen t3 interfere "7th A? T/2 whereas it Sl9"lftcwtly 5horte"s R-S" T/2 and red"cls R-SV-induced hyperbilirubinaemia. A5 bi:ir"bi" hepatic uptake shares with R-S" a cxn,"n, carrier mediated pathway ltlin Sci 1985;68:675-SO!, the effect of SAMe may be due to the improvement of hepatocyte membrane fluidity. These findings provide s"pport to the "se of SAM8 as an anticholestatic agent in cirrhotics.
AP T/2 ImInI
R-SV T/2 (Inin> B-A”t W"g,di,4hl
before 2% 4