- Email: [email protected]
Dietary habits do not influence plasma antibodies against oxidized LDL level in a wide sample of healthy subjects: The brisighella heart study
XVII S.I.S.A. National Congress OVERWEIGHT AND OBESITY I N THE SHADOW OF MONGIBELLO
321 ATTITUDES ABOUT SMOKING HABIT. INVESTIGATION SAMPLE OF ITALIAN TEENAGE STUDENTS
IN
A
Bertino G, Ardiri A, Fisichella A, Pepi F, Occhipinti D, Rainolo M S Bottazzo, A Nogara, G Pagan, G Bittolo Bon Department of internal medicine University of Catania Obesity is a real illness, and represents a risk factor for many chronic pathologies which, according to an evaluation of the world population, cause approximately 75% of all deaths. I t is a growing public health problem. Data from the Italian Statistics Institute (ISTAT) show an increment of obesity and average weight in the Italian population in the last few years. Obesity is known to cause a predisposition to arterial hypertension, dyslipidemia, blood hypercoagulation, insulin resistance and elevated PCR values, all of which are associated with a high risk of myocardial infarction, stroke and arteriosclerosis of the coronary arteries. These findings have prompted us to evaluate the prevalence of obesity in a population sample and its correlation with diverse pathological profiles. METHODS. Between January and December 2002, 823 consecutive individuals from different urban centres of the province of Catania, referred to our Day Hospital service for various conditions (chronic liver disease, diabetes mellitus, arterial hypertension, BPCO) were enrolled in our study. RESULTS. Obesity within the selected group was: total patients (823) Obese (295)35.84%) M(171) F(118) Average age(61); Isolated obesity: 57 Obesity + DM=17; Obesity + IA= 22; Obesity + DM + IA + Steatosis:113 Obesity + steatosis: 86. CONCLUSIONS. Our research carried out in the province of Catania shows a relevant obesity rate (BMI>30.O, 35.84%). Only in 19.3% it represented the sole clinical manifestation while in 80.6% it was always associated with important pathologies, such as diabetes mellitus, arterial hypertension and dyslipidemia. The association of obesity and these pathologies represents a furtheF increase in the overall cardiovascular risk. Hence, any treatment of these pathologies must take into account the prevention and treatment of obesity.
ULSS 12 Venete, Aterosclerosi.
U.O.
Medicina
Generale,
Centro
Regionale
Reducing the prevalence of smoking among teenagers is an important public health goal, as epidemiological studies have shown that smoking is increasing among young people. Adolescents generally begin to smoke at about age 14-15 years. In order to start specific anti-smoking campaign for adolescents is it important to detect which are the attitudes about smoking habit among youth. By mean of an anonymous self-administered questionnaire, we studied a sample of 251 teenager students (64% females, 36% males, age 14-15 years), in Venice and Mestre. The questions were directed to assess their knowledge of the chemical nature of tobacco and their awareness of the dangers to health caused by smoking. Indeed, specific questions dealt with the motivations that could bring adolescents to smoking. As many as 96% of the students filled it the questionnaire completely. Based on the answers, we were able to detect that all the interviewees were aware that tobacco smoking is harmful. The risk for smoke addiction was known to the majority (74%) of the teenagers tested in our study. Only the 32% of our sample declared to know that nicotine is a chemical product present in tobacco smoke. As to the motivations that may induce a teenager to begin smoking, 52% referred to the imitation of adult behaviour, 24% to the possibility of overcoming shyness or anxiety, 16% to mere curiosity and 8% provided other motivations. Conclusions: Our results provide evidence that the adolescent students of our sample were aware that smoking is harmful but still consider it a way to emancipate from adolescent status, Anti smoking strategies directed to youth would have to consider the idea that young people have of tobacco as a means to overcome adolescent troubles.
DIETARY HABITS DO NOT INFLUENCE PLASMA ANTIBODIES AGAINST OXIDIZED LDL LEVEL I N A WIDE SAMPLE OF HEALTHY SUBJECTS: THE BRISIGHELLA HEART STUDY
RELATIVE ROLE OF MAJOR RISK FACTORS FOR TYPE 2 DIABETES DEVELOPMENT IN THE HISTORICAL COHORT OF THE BRISIGHELLA HEART STUDY: AN 8-YEARS FOLLOW-UP
AFG Cicero, A Fiorito, T Rontini, E Grandi, Z Sangiorgi, A Dormi, A Geddi
AFG Cicero, A Dormi, S D'Addato, E Grandi, Z Sangiorgi, A Gaddi
Atherosclerosis Centre "GC Descovich" - Clinical Medicine and Applied Biotechonology Dept. - University of Bologna, Italy Aim: to evaluate the ox-LDL Ab plasma level in a wide sample of subjects without clinical signs of atherosclerosis selected from the database of the Brisighetla Heart Study. Methods: 134 men and 192 women with comparable age (48.15=t:11.26 years) and plasma LDL-C level (146.00:E31.39 mg/dL). Nutritional habits have been evaluatad through the "Seven-days questionnaire" (Eur J Clin Nutr 2001,55(2):97-106) that gives information about the mean daily intake of energy sources, main vitamins and minerals. Results: Overall no significant differences have been found between men and women oxLDL Ab plasma levels (370.1=l=379.8mU/ml vs. 404.4:l:345.8mU/ml; p>O.O01). Dividing the population in age quartHes, in men ox-LDL Ab plasma level is significantly higher in the first 2 quartiles (age<57 years) than in the second 2 (p
Atherosclerosis Research Centre ~GC Descovich" - Clinical Medicine and Applied Biotechonology Dept. - University of Bologna, Italy Aim: To quantify the relative role of different type 2 diabetes risk factors in the long-term development of type 2 DM in an Italian rural population sample. Methods: The Brisighella Heart Study (1972-2003) is a prospective, population-based longitudinal epidemiological cohort involving 2939 randomly selected subjects, aged 14 to 84 years, residing in the rural town of Brisighella. For this study, we selected 1442 age-matched adult subjects (M:712, F:730) consecutively visited during the last 3 BHS surveys (1988, 1992, 1996), with comparable baseline BMI, FPG and smoking habit. The Cox regression analysis was used to determine the independent prognostic significance of age, BMI, BP, FPG, TG, and HDL-C for type 2 DM development on an 8-year long follow-up. Results: In our population sample, age appears to be a significant predictor of type 2 DM when inserted alone in the model (p=O.O07), but it is completely not relevant when adjusted for baseline BMI and FPG. Among subjects affected by IFG, the DM incidence/year has been estimated to be 5.3% for men and 3.9% for women (p=0.009). In the whole population sample, FPG
321 ATTITUDES ABOUT SMOKING HABIT. INVESTIGATION SAMPLE OF ITALIAN TEENAGE STUDENTS
IN
A
Bertino G, Ardiri A, Fisichella A, Pepi F, Occhipinti D, Rainolo M S Bottazzo, A Nogara, G Pagan, G Bittolo Bon Department of internal medicine University of Catania Obesity is a real illness, and represents a risk factor for many chronic pathologies which, according to an evaluation of the world population, cause approximately 75% of all deaths. I t is a growing public health problem. Data from the Italian Statistics Institute (ISTAT) show an increment of obesity and average weight in the Italian population in the last few years. Obesity is known to cause a predisposition to arterial hypertension, dyslipidemia, blood hypercoagulation, insulin resistance and elevated PCR values, all of which are associated with a high risk of myocardial infarction, stroke and arteriosclerosis of the coronary arteries. These findings have prompted us to evaluate the prevalence of obesity in a population sample and its correlation with diverse pathological profiles. METHODS. Between January and December 2002, 823 consecutive individuals from different urban centres of the province of Catania, referred to our Day Hospital service for various conditions (chronic liver disease, diabetes mellitus, arterial hypertension, BPCO) were enrolled in our study. RESULTS. Obesity within the selected group was: total patients (823) Obese (295)35.84%) M(171) F(118) Average age(61); Isolated obesity: 57 Obesity + DM=17; Obesity + IA= 22; Obesity + DM + IA + Steatosis:113 Obesity + steatosis: 86. CONCLUSIONS. Our research carried out in the province of Catania shows a relevant obesity rate (BMI>30.O, 35.84%). Only in 19.3% it represented the sole clinical manifestation while in 80.6% it was always associated with important pathologies, such as diabetes mellitus, arterial hypertension and dyslipidemia. The association of obesity and these pathologies represents a furtheF increase in the overall cardiovascular risk. Hence, any treatment of these pathologies must take into account the prevention and treatment of obesity.
ULSS 12 Venete, Aterosclerosi.
U.O.
Medicina
Generale,
Centro
Regionale
Reducing the prevalence of smoking among teenagers is an important public health goal, as epidemiological studies have shown that smoking is increasing among young people. Adolescents generally begin to smoke at about age 14-15 years. In order to start specific anti-smoking campaign for adolescents is it important to detect which are the attitudes about smoking habit among youth. By mean of an anonymous self-administered questionnaire, we studied a sample of 251 teenager students (64% females, 36% males, age 14-15 years), in Venice and Mestre. The questions were directed to assess their knowledge of the chemical nature of tobacco and their awareness of the dangers to health caused by smoking. Indeed, specific questions dealt with the motivations that could bring adolescents to smoking. As many as 96% of the students filled it the questionnaire completely. Based on the answers, we were able to detect that all the interviewees were aware that tobacco smoking is harmful. The risk for smoke addiction was known to the majority (74%) of the teenagers tested in our study. Only the 32% of our sample declared to know that nicotine is a chemical product present in tobacco smoke. As to the motivations that may induce a teenager to begin smoking, 52% referred to the imitation of adult behaviour, 24% to the possibility of overcoming shyness or anxiety, 16% to mere curiosity and 8% provided other motivations. Conclusions: Our results provide evidence that the adolescent students of our sample were aware that smoking is harmful but still consider it a way to emancipate from adolescent status, Anti smoking strategies directed to youth would have to consider the idea that young people have of tobacco as a means to overcome adolescent troubles.
DIETARY HABITS DO NOT INFLUENCE PLASMA ANTIBODIES AGAINST OXIDIZED LDL LEVEL I N A WIDE SAMPLE OF HEALTHY SUBJECTS: THE BRISIGHELLA HEART STUDY
RELATIVE ROLE OF MAJOR RISK FACTORS FOR TYPE 2 DIABETES DEVELOPMENT IN THE HISTORICAL COHORT OF THE BRISIGHELLA HEART STUDY: AN 8-YEARS FOLLOW-UP
AFG Cicero, A Fiorito, T Rontini, E Grandi, Z Sangiorgi, A Dormi, A Geddi
AFG Cicero, A Dormi, S D'Addato, E Grandi, Z Sangiorgi, A Gaddi
Atherosclerosis Centre "GC Descovich" - Clinical Medicine and Applied Biotechonology Dept. - University of Bologna, Italy Aim: to evaluate the ox-LDL Ab plasma level in a wide sample of subjects without clinical signs of atherosclerosis selected from the database of the Brisighetla Heart Study. Methods: 134 men and 192 women with comparable age (48.15=t:11.26 years) and plasma LDL-C level (146.00:E31.39 mg/dL). Nutritional habits have been evaluatad through the "Seven-days questionnaire" (Eur J Clin Nutr 2001,55(2):97-106) that gives information about the mean daily intake of energy sources, main vitamins and minerals. Results: Overall no significant differences have been found between men and women oxLDL Ab plasma levels (370.1=l=379.8mU/ml vs. 404.4:l:345.8mU/ml; p>O.O01). Dividing the population in age quartHes, in men ox-LDL Ab plasma level is significantly higher in the first 2 quartiles (age<57 years) than in the second 2 (p
Atherosclerosis Research Centre ~GC Descovich" - Clinical Medicine and Applied Biotechonology Dept. - University of Bologna, Italy Aim: To quantify the relative role of different type 2 diabetes risk factors in the long-term development of type 2 DM in an Italian rural population sample. Methods: The Brisighella Heart Study (1972-2003) is a prospective, population-based longitudinal epidemiological cohort involving 2939 randomly selected subjects, aged 14 to 84 years, residing in the rural town of Brisighella. For this study, we selected 1442 age-matched adult subjects (M:712, F:730) consecutively visited during the last 3 BHS surveys (1988, 1992, 1996), with comparable baseline BMI, FPG and smoking habit. The Cox regression analysis was used to determine the independent prognostic significance of age, BMI, BP, FPG, TG, and HDL-C for type 2 DM development on an 8-year long follow-up. Results: In our population sample, age appears to be a significant predictor of type 2 DM when inserted alone in the model (p=O.O07), but it is completely not relevant when adjusted for baseline BMI and FPG. Among subjects affected by IFG, the DM incidence/year has been estimated to be 5.3% for men and 3.9% for women (p=0.009). In the whole population sample, FPG