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Digital method for dynamic trans-epidermal water loss measurement (TEWL)
Posters - Paedimric
on the frontal area. These data suggest that differences observed clinically between different zones of the face are paralleled not only by differences in CL but also in TEWL. skin color and roughness.
El
P331
Facial skin circadian women documented methods
rhythms of healthy with non-invasive
I. Le Fur’, A. Reinberg2, S. Lopezt. F. Morizott, M. Mechkouri’, E. Tschachler’,“. ‘CE.R.I.E.S., Neuilly Seine: ’ UttitC Paris. Frurtce;
SW de Cltrotrobiologie. Fotulntiorr A. de Rothscltild. 3Univer,sity of Vienrtct, Viertrtu, Austria
Although circadian rhythms have been studied in human skin, few experiments have been devoted to facial skin. The present study. conducted on 8 women during a 48 h span, aimed to document around-the-clock changes in a set of biophysical variables. including skin capacitance, temperature, pH. transepidermal water loss (TEWL). colour and sebum excretion rate (SER). Free salivary cortisol was investigated as a reference rhythm. Circadian rhythms were validated for all variables (ANOVA) with two exceptions, skin temperature and b* chromametric value. For most of the variables trough was more pronounced than peak. SER trough time occurs around midnight, TEWL in the early night and pH around 4:00 a.m. These results confrm the existence of circadian rhythms of facial skin in a set of biophysical variables. Therefore. the comparison of skin biophysical properties needs to take into account the time of measurements. ) P332 1 Full profile biophysical
of women’s parameters
facial skin for three
S. Lopez’, I. Le Fur’, F. Morizot’. G. Heuvint, C. Guinott. E. Tschachler’~‘. ‘CE.R./.ES.. Neuilly sur Seine. Frmce; ’ Uttiversitv
of Wenrrtr,
Vietrrta.
Austrict
To investigate anatomical differences of facial skin, full profles of facial skin were established for transepidermal water loss (TEWL). skin temperature and sebum casual level (CL). Measurements were performed on a total of 90 adjacent test sites of I ctn* on the forehead, the 2 cheeks and the chin of 5 women. The 3 parameters showed a symmetrical distribution about the facial median line. Mean values on the 2 cheeks were comparable. CL distribution pointed out a “T-zone” with high values on the forehead. on the chin and a gradient from the nose (high values) to the malar zone (small values) on the cheek area. Temperature distribution followed a similar pattern. TEWL distribution on the cheeks also showed a gradient and smallest values were observed on the forehead. For all parameters, only minor variations were found within the forehead and the chin whereas cheeks exhibited a distinct gradient from the nose to the malar zone. Our data demonstrated that biophysical skin properties differ considerably between the different facial areas.
S263
dennatologp
IP333
Non calcifying pilomatricoma: Ultrasound imaging of an early morphological stage
Ph. Bahadoran. V.M. Bonaldi, A. Grimaud, A. Chevallier, J.-N. Bruneton, J.-P Ortonne. CHU de Nice, France Pilomatricoma is a benign epidermal appendage tumor with differentiation toward hair matrix cells. It has been originally described as a “calcifying epithelioma”, but about 15% of pilomatricomas are not calcified. A 6-year old girl presented a gradually increasing painless nodule of the left shoulder for about 7 months. Clinical examination showed a small firm subcutaneous mass of the left subclavicular fossa. Ultrasound examination (US) demonstrated an oval-shaped mass, superficially located in and sharply demarcated from the subcutaneous fat. No calcification was detected and no blood-flow was demonstrated by color-doppler. The child was referred to surgery with the provisional diagnosis of non-aggressive soft tissue tumor. Histologic study established the diagnosis of noncalcifying pilomatricoma. The sparse radiologic descriptions of pilomatricomas have all referred to calcified subcutaneous masses. This case shows that lack of calcification in US imaging of a subcutaneous mass should not rule out the diagnosis of pilomatricoma.
IP334
Digital method for dynamic transepidermal water loss measurement (TEWL)
H. Laudanska, T. Reduta. Deportment Venereology.
Medicul
of Dermatology Bialystok, Polmtd
University,
and
The aim of the study was to present a modified, digital, computerised method for dynamic. continuous TEWL measurement from defined skin sites. The system is based on the open chamber instrument with two humidity and temperature sensors, which measure the water evaporation gradient on the surface of the skin. The continuously collected signals are converted by analogue-digital transducer and transmitted to the personal computer. The rate of disappearance of TEWL values for an hour after removal of sodium lauryl sulphate (SLS) from forearm skin was studied in healthy volunteers. This studies indicate the usefulness of the method in the evaluation of rapidly changing skin permeability.
Paediatric dermatology 1P335 1 Infantile perineal be a manifestation atrophicus
pyramidal protrusion of lichen sclerosus
can et
M.J. Crucest, A. Losadat, G.I. Dovalt, C. Ocampot, L. Sardfi2, C. De la Tom?. ‘Serv. Porttevedrcl; 2Hospital Hahra, Cu6a
Background:
Derntatologia M. Enriquez
Hospital Ptvvincial “La Bent!!ca Gallegu”,
Lu
Kayashima et al have recently called Infanti/e pea perineal infantile lesion previously described as a “skin tag/fold”. It appears on the perineal median raphe of girls as a pyramidal soft tissue swelling; covered by smooth. red or rose-colored skin. Its pathogen&s is ‘unknown. riannl
pyrantidnlprotusiorr
on the frontal area. These data suggest that differences observed clinically between different zones of the face are paralleled not only by differences in CL but also in TEWL. skin color and roughness.
El
P331
Facial skin circadian women documented methods
rhythms of healthy with non-invasive
I. Le Fur’, A. Reinberg2, S. Lopezt. F. Morizott, M. Mechkouri’, E. Tschachler’,“. ‘CE.R.I.E.S., Neuilly Seine: ’ UttitC Paris. Frurtce;
SW de Cltrotrobiologie. Fotulntiorr A. de Rothscltild. 3Univer,sity of Vienrtct, Viertrtu, Austria
Although circadian rhythms have been studied in human skin, few experiments have been devoted to facial skin. The present study. conducted on 8 women during a 48 h span, aimed to document around-the-clock changes in a set of biophysical variables. including skin capacitance, temperature, pH. transepidermal water loss (TEWL). colour and sebum excretion rate (SER). Free salivary cortisol was investigated as a reference rhythm. Circadian rhythms were validated for all variables (ANOVA) with two exceptions, skin temperature and b* chromametric value. For most of the variables trough was more pronounced than peak. SER trough time occurs around midnight, TEWL in the early night and pH around 4:00 a.m. These results confrm the existence of circadian rhythms of facial skin in a set of biophysical variables. Therefore. the comparison of skin biophysical properties needs to take into account the time of measurements. ) P332 1 Full profile biophysical
of women’s parameters
facial skin for three
S. Lopez’, I. Le Fur’, F. Morizot’. G. Heuvint, C. Guinott. E. Tschachler’~‘. ‘CE.R./.ES.. Neuilly sur Seine. Frmce; ’ Uttiversitv
of Wenrrtr,
Vietrrta.
Austrict
To investigate anatomical differences of facial skin, full profles of facial skin were established for transepidermal water loss (TEWL). skin temperature and sebum casual level (CL). Measurements were performed on a total of 90 adjacent test sites of I ctn* on the forehead, the 2 cheeks and the chin of 5 women. The 3 parameters showed a symmetrical distribution about the facial median line. Mean values on the 2 cheeks were comparable. CL distribution pointed out a “T-zone” with high values on the forehead. on the chin and a gradient from the nose (high values) to the malar zone (small values) on the cheek area. Temperature distribution followed a similar pattern. TEWL distribution on the cheeks also showed a gradient and smallest values were observed on the forehead. For all parameters, only minor variations were found within the forehead and the chin whereas cheeks exhibited a distinct gradient from the nose to the malar zone. Our data demonstrated that biophysical skin properties differ considerably between the different facial areas.
S263
dennatologp
IP333
Non calcifying pilomatricoma: Ultrasound imaging of an early morphological stage
Ph. Bahadoran. V.M. Bonaldi, A. Grimaud, A. Chevallier, J.-N. Bruneton, J.-P Ortonne. CHU de Nice, France Pilomatricoma is a benign epidermal appendage tumor with differentiation toward hair matrix cells. It has been originally described as a “calcifying epithelioma”, but about 15% of pilomatricomas are not calcified. A 6-year old girl presented a gradually increasing painless nodule of the left shoulder for about 7 months. Clinical examination showed a small firm subcutaneous mass of the left subclavicular fossa. Ultrasound examination (US) demonstrated an oval-shaped mass, superficially located in and sharply demarcated from the subcutaneous fat. No calcification was detected and no blood-flow was demonstrated by color-doppler. The child was referred to surgery with the provisional diagnosis of non-aggressive soft tissue tumor. Histologic study established the diagnosis of noncalcifying pilomatricoma. The sparse radiologic descriptions of pilomatricomas have all referred to calcified subcutaneous masses. This case shows that lack of calcification in US imaging of a subcutaneous mass should not rule out the diagnosis of pilomatricoma.
IP334
Digital method for dynamic transepidermal water loss measurement (TEWL)
H. Laudanska, T. Reduta. Deportment Venereology.
Medicul
of Dermatology Bialystok, Polmtd
University,
and
The aim of the study was to present a modified, digital, computerised method for dynamic. continuous TEWL measurement from defined skin sites. The system is based on the open chamber instrument with two humidity and temperature sensors, which measure the water evaporation gradient on the surface of the skin. The continuously collected signals are converted by analogue-digital transducer and transmitted to the personal computer. The rate of disappearance of TEWL values for an hour after removal of sodium lauryl sulphate (SLS) from forearm skin was studied in healthy volunteers. This studies indicate the usefulness of the method in the evaluation of rapidly changing skin permeability.
Paediatric dermatology 1P335 1 Infantile perineal be a manifestation atrophicus
pyramidal protrusion of lichen sclerosus
can et
M.J. Crucest, A. Losadat, G.I. Dovalt, C. Ocampot, L. Sardfi2, C. De la Tom?. ‘Serv. Porttevedrcl; 2Hospital Hahra, Cu6a
Background:
Derntatologia M. Enriquez
Hospital Ptvvincial “La Bent!!ca Gallegu”,
Lu
Kayashima et al have recently called Infanti/e pea perineal infantile lesion previously described as a “skin tag/fold”. It appears on the perineal median raphe of girls as a pyramidal soft tissue swelling; covered by smooth. red or rose-colored skin. Its pathogen&s is ‘unknown. riannl
pyrantidnlprotusiorr