Double Nicking by RNA-Guided CRISPR Cas9 for Enhanced Genome Editing Specificity

Double Nicking by RNA-Guided CRISPR Cas9 for Enhanced Genome Editing Specificity

Errata Double Nicking by RNA-Guided CRISPR Cas9 for Enhanced Genome Editing Specificity F. Ann Ran, Patrick D. Hsu, Chie-Yu Lin, Jonathan S. Gootenbe...

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Errata

Double Nicking by RNA-Guided CRISPR Cas9 for Enhanced Genome Editing Specificity F. Ann Ran, Patrick D. Hsu, Chie-Yu Lin, Jonathan S. Gootenberg, Silvana Konermann, Alexandro E. Trevino, David A. Scott, Azusa Inoue, Shogo Matoba, Yi Zhang, and Feng Zhang* *Correspondence: [email protected] http://dx.doi.org/10.1016/j.cell.2013.09.040

(Cell 154, 1380–1389; August 29, 2013) We wish to correct errors introduced during the preparation of two figures and two supplemental tables in the above article. In the ‘‘DYRK1A’’ plot of Figure 2B, we inadvertently omitted seven additional data points that were presented in Table S1. In Figure 4B, the labels for two panels were inadvertently switched. Tables S1 and S2, which report the sequences of sgRNAs, contained several typographical errors. None of these errors affect any of the results presented or their interpretations. Corrected figures appear below and with the article online. Tables S1 and S2 have also been updated online. We regret these errors and apologize for the inconvenience that they may have caused.

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Figure 2. Double Nicking Facilitates Efficient Genome Editing in Human Cells

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Cell 155, 478–480, October 10, 2013 ª2013 Elsevier Inc. 479

Figure 4. Double Nicking Allows Insertion into the Genome via HDR in Human Cells

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480 Cell 155, 478–480, October 10, 2013 ª2013 Elsevier Inc.

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