Drug Abuse as a Probable Risk Factor for Palatine Alterations: Report of 2 Cases

Drug Abuse as a Probable Risk Factor for Palatine Alterations: Report of 2 Cases

OOOO Volume 120, Number 2 Burning mouth syndrome (BMS) is a burning sensation or dysesthesia in an oral mucosa where no lesion was identified. A 57-yea...

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OOOO Volume 120, Number 2 Burning mouth syndrome (BMS) is a burning sensation or dysesthesia in an oral mucosa where no lesion was identified. A 57-year-old female complained of a strong burning sensation on the tongue, buccal mucosa, and lips, together with a significant reduction in salivation. No alteration of the oral mucosa was detected on intraoral clinical examination. The patient reported using various medications to control hypertension, diabetes, hyperlipidemia, and asthma. Symptoms related to BMS appeared after a hypertensive crisis, resulting in a change in the pharmacological treatment regimen (an increase in the dose of captopril and the addition of enalapril). Based on the current clinical features, the dose of enalapril was reduced and the captopril was replaced with losartan. The patient was being followed, her salivation had returned to normal, and the BMS symptoms had diminished. In patients with BMS, it is important to make the differential diagnosis in order to establish an appropriate treatment regimen, thus improving quality of life.

PCC-176 - CALCIFYING ODONTOGENIC CYST ASSOCIATED WITH COMPLEX ODONTOMA: CASE REPORT. LORENA CASTRO MARIANO, ANTONIO LUCINDO PINTO SOBRINHO, DEYVID REBOUÇAS, JAMILE DE OLIVEIRA SÁ, ALENA PEIXOTO MEDRADO, SILVIA REGINA DE ALMEIDA REIS, ANTONIO MARCIO TEIXEIRA MARCHIONNI. ESCOLA BAHIANA DE MEDICINA E SAÚDE PÚBLICA. Calcifying odontogenic cyst presents as an intraosseous cystic cavity lined with odontogenic epithelium with evident keratinization and calcification. Also known as Gorlin’s cyst, this lesion primarily affects the anterior region of the maxilla and can be associated with other odontogenic lesions, such as odontoma. A 4-year-old male presented to our oral and maxillofacial surgery service with his mother, who reported that her son had a swelling, with slow and asymptomatic growth, in the anterior region of the mandible. Extraoral examination revealed mild swelling, which was confirmed in the intraoral examination. Radiography showed a mixed lesion with a radiolucent halo and structures of varying degrees of radiopacity at its center. An incisional biopsy was performed, and the histopathological findings indicated that the lesion was cystic in nature, with ghost cells in the odontogenic epithelium. The lesion was treated surgically, and there was no evidence of recurrence after 6 months.

PCC-177 - CERVICOFACIAL NECROTIZING FASCIITIS IN ASSOCIATION WITH FACIAL TRAUMA WITHOUT EXTERNAL CONTAMINATION. FERNANDO ANTONIO PORTELA DA CUNHA FILHO, MANUEL ANTONIO GÓRDON-NÚÑEZ, CASSIANO FRANCISCO WEEGE NONAKA. UNIVERSIDADE ESTADUAL DA PARAÍBA. Necrotizing fasciitis is characterized by polymicrobial invasive infection with extensive necrosis of the superficial fascia, causing thrombosis of the vessels and skin necrosis with extensive systemic toxicity. Here, we report a case of cervicofacial necrotizing fasciitis, associated with closed facial trauma (without external contamination), in an adult, alcoholic, male who sought treatment 5 days after the trauma. Tomography of the face showed foci of infection in the soft tissue and fracture of the right zygomatic bone. The initial treatment was aggressive surgical debridement with removal of all necrotic tissue, including the masseter, lateral pterygoid, and buccinator muscles. The tissues were analyzed and microbiological testing revealed positivity for Klebsiella pneumoniae. Although antibiotic therapy with meropenem was

ABSTRACTS Abstracts e59 instituted, the patient succumbed to sepsis and died. Early diagnosis of necrotizing fasciitis is critical, and the most commonly accepted treatment includes radical surgical intervention and the timely administration of broad-spectrum antibiotics.

PCC-178 - CHRONIC INFLAMMATORY ODONTOGENIC LESION WITH ATYPICAL CELLS: CASE REPORT. LÍVIA OLIVEIRA QUIRINO, JOSÉ DE AMORIM LISBOA NETO, MARCUS ANTÔNIO BRÊDA JÚNIOR, VANIO SANTOS COSTA, CAMILA MARIA BEDER RIBEIRO, JANAINA ANDRADE LIMA SALMOS BRITO, RICARDO VIANA BESSA NOGUEIRA. UNIVERSIDADE FEDERAL DE ALAGOAS. Most inflammatory conditions in the oral region are readily distinguishable from aggressive tumors by routine. Occasionally, however, they can present lytic behavior and be mistaken for tumor processes. Only meticulous histological scrutiny reveals their true nature. A 26-year-old female presented with a chronic lytic lesion, associated with a horizontal impacted mandibular third molar, infiltrating the periapical region of the second molar. Hematoxylineeosin staining of histological sections revealed fragments of fibrous connective tissue with inflammatory cells and some atypical plasma cells, suggesting an uncommon chronic inflammatory lesion. Kappa and Lambda immunohistochemistry were performed. A polyclonal reactive process was observed, confirming the benign, odontogenic nature of the lesion. At 5 months of follow-up, no recurrence was reported; clinical and radiographic examination showed normal bone healing.

PCC-179 - KERATOCYSTIC ODONTOGENIC TUMOR: CASE REPORT. LUCAS EMANUEL TENÓRIO FERNANDES TELES, CRISTINNE ANDRADE MELO, MARIA DE FÁTIMA BATISTA DE MELO, CAETANO GUILHERME CARVALHO PONTES, SARA JULIANA DE ABREU VASCONCELLOS, RICARDO LUIZ CAVALCANTI DE ALBUQUERQUE JÚNIOR. UNIVERSIDADE TIRADENTES. Keratocystic odontogenic tumor (KOT) is a benign lesion recently classified as cyst-like odontogenic tumor, derived from the dental lamina that is locally destructive and tends to recur after conservative surgical treatment. A 76-year-old White male, a farmer, presented with a 1-year history of asymptomatic vestibular swelling in the right premaxilla. The lesion was approximately 3.0 cm in diameter and was nonphlogistic. Imaging revealed a well-circumscribed multilocular osteolytic lesion. Histological examination of the excisional biopsy sample showed a pathological cavity lined with thin epithelium that sometimes was detached from the fibrous capsule, a pathognomonic feature of KOT, which was the diagnosis. This case highlights the aspects of KOT in a diagnosis based on clinical, radiological, and pathologic features, which seems to represent one of the most commons lesions in the gnathic bones.

PCC-180 - DRUG ABUSE AS A PROBABLE RISK FACTOR FOR PALATINE ALTERATIONS: REPORT OF 2 CASES. DANIELLE RESENDE CAMISASCA BARROSO, TÂNIA REGINA GRÃO VELLOSO, SERGIO LINS DE AZEVEDO VAZ, FABIANO DE AZEVEDO RIBEIRO, DANIELA NASCIMENTO SILVA, ROSSIENE MOTTA BERTOLLO, LILIANA APARECIDA PIMENTA DE BARROS. UNIVERSIDADE FEDERAL DO ESPÍRITO SANTO.

ORAL AND MAXILLOFACIAL PATHOLOGY e60 Abstracts The abuse of cocaine and related drugs can cause significant local ischemic necrosis and destruction. Here, we describe 2 patients with palatal alterations. A 38-year-old female who was a smoker presented with a 0.5-cm perforation in the midline of the hard palate. Tests for syphilis, hepatitis, HIV infection, and leishmaniasis were negative. Because she was a cocaine trafficker, the perforation was assumed to be drug-related. The second patient, a male who admitted to smoking tobacco and marijuana, presented with an enamel defect in the central incisors, consistent with pipe abrasion, and complained of diffuse pain. A necrotic 1-cm ulcer was observed in his posterior hard palate. Necrotizing sialometaplasia was confirmed by histopathological examination of a biopsy sample. We noted marked improvement after 1 month and complete healing after 4 months. Because cocaine abuse is increasing, dentists should be aware of the possible oral manifestations. Accurate social and clinical history taking is critical to making the correct diagnosis, as well as the differential diagnosis with other diseases.

PCC-181 - ERUPTED COMPOUND ODONTOMA: A CASE REPORT. ANTONIO DIONIZIO DE ALBUQUERQUE NETO, DARLAN KELTON FERREIRA CAVALCANTE, LUIZ ARTHUR BARBOSA DA SILVA, JESUS JULIO GAMELEIRA FORTES, JOSÉ DE AMORIM LISBOA NETO, MARCUS ANTONIO BRÊDA JÚNIOR. UNIVERSIDADE FEDERAL DE ALAGOAS. Odontomas are hamartomatous developmental malformations of the dental tissues, consisting of enamel, dentin, cementum, and dental pulp. They can be classified as complex or compound and as intraosseous or peripheral. They are associated with tooth impaction, anodontia, infection, pain, root resorption, and malocclusion. Erupted odontomas are uncommon, and there is a relationship with the eruption forces in the impacted teeth that results in the eruption of the odontoma. Here, we report the case of a 60-year-old female who had a hard gingival swelling and exhibited portions of yellowish partially calcified tissue on the alveolar ridge. Radiographs revealed an impacted tooth associated with multiple small dental structures that characterize compound odontoma.

PCC-182 - ERYTHEMA MULTIFORME LESIONS TRIGGERED BY HERPES LABIALIS. LAURA GREIN CAVALCANTI, BRUNA BASSO FONSECA, CAMILA PINHEIRO FURQUIM, CLETO MARIOSVALDO PIAZZETTA, JOSÉ MIGUEL AMENÁBAR CÉSPEDES, CASSIUS CARVALHO TORRES-PEREIRA. UNIVERSIDADE FEDERAL DO PARANÁ. Erythema multiform (EM) is an immune-mediated mucocutaneous disease, characterized by bullous and ulcerative lesions in the oral mucosa. It is usually associated with a previous herpes simplex infection. A 21-year-old male patient was referred to an oral medicine clinic with a confirmed diagnosis of EM. He had target skin lesions on his legs and feet. At clinical evaluation, we observed white lesions, symptomatic ulcers, and bullous injuries on the tongue and buccal mucosa, which were preventing food intake. The patient also presented herpes labialis. After 1 week of treatment with oral prednisone and antifungal therapy, a considerable decrease in the size of the oral lesions was observed. Clinical control of EM is challenging because corticosteroids, although improving the autoimmune manifestations, can provoke reactivation of the herpes virus.

OOOO August 2015 However, prednisone and famciclovir can help control that condition.

PCC-183 - FETAL TYPE EXTRACARDIAC RHABDOMYOMA IN TONGUE: CASE REPORT. FLÁVIA LIMA KLEINSORGEN MOTTA, ARLEY SILVA JUNIOR, KARLA BIANCA FONTES, ELIANE PEDRA DIAS, RAFAELA ELVIRA ROZZA, ISADORA FOLLAK DE SOUZA, KARIN SOARES GONÇALVES CUNHA. UNIVERSIDADE FEDERAL FLUMINENSE. Fetal type extracardiac rhabdomyoma is a rare benign tumor of striated muscle origin, usually found in the head and neck region. A 2-month-old female was referred by her pediatrician for evaluation of a congenital tumor-like lesion in the anterior third of the tongue. Ultrasound examination showed expansive hypoechoic formation with defined limits, measuring 2.1 cm at its greatest diameter. Fine-needle aspiration cytology was inconclusive. An incisional biopsy was performed, and the diagnosis of fetal type extracardiac rhabdomyoma was established on the basis of the morphological aspects and the expression of myogenin and Ki-67. Conservative excision of the lesion was performed, and there was no evidence of recurrence after 3 years. Fetal type extracardiac rhabdomyoma of the tongue is rare. The treatment is complete surgical excision.

PCC-184 - FIBRODYSPLASIA OSSIFICANS PROGRESSIVA: A CASE REPORT AND CONSERVATIVE DENTAL MANAGEMENT. FILIPE NOBRE CHAVES, EALBER CARVALHO MACEDO LUNA, MALENA REGINA DE FREITAS E SILVA, FRANCISCO SAMUEL RODRIGUES CARVALHO, FABRÍCIO BITU SOUSA, FÁBIO WILDSON GURGEL COSTA, KARUZA MARIA ALVES PEREIRA. UNIVERSIDADE FEDERAL DO CEARÁ e CAMPUS SOBRAL. Fibrodysplasia ossificans progressiva (FOP) is a rare hereditary connective tissue disease characterized by widespread soft tissue ossification and congenital stigmata of the extremities. Clinical and radiological diagnosis is essential, because invasive procedures, as can be caused by dental treatment, exacerbate the disease. The clinical features include malformation of the big toe, reduction defects of all digits, deafness, baldness, and mental retardation. This study aimed to report the case of a 32-year-old female patient with FOP and discuss the dental management of the case. Conservative dental procedures, such as oral hygiene instructions and expectant restorative treatment, were performed. At 18 months of follow-up, no heterotopic ossifications resulting from dental treatment had been observed. Palliative treatments are available, and prevention plays an important role in dental patients with FOP.

PCC-185 - FIBROUS DYSPLASIA OF MAXILLA: A CASE REPORT. GERSON DE OLIVEIRA PAIVA NETO, JULIANA MARIA SOUZA DE OLIVEIRA, LIA MIZOBE ONO, SILVIA CRISTINA OLIVEIRA BRANDÃO, TÂNIA CRISTINA CHICRE ALCÂNTARA DE BRITO, JULIANA PINTO DE SOUZA, TATIANA NAYARA LIBÓRIO KIMURA. UNIVERSIDADE FEDERAL DO AMAZONAS. Fibrous dysplasia of bone is a disease characterized by healthy bone being replaced with fibrous tissue and a newly formed mineralized product. A 35-year-old Black female was referred to a school of dentistry for evaluation of a volumetric growth, in the posterior maxilla, near the molars, that