Drug-drug and drug-food interactions

European Journal of Pharnracologr, ,IJ 1991 Elsevier Science Publishers ADONIS 001429999100312N

195 ( 1991) 415-416 B.V. 0014-2999/91/$03.50

415

EJP 20803

Corrigen

K.D. Wild, T. Vanderah. H.I. Mosberg and F. Porreca, channels, European J. Pharmacol. 193 (1991) 135-136.

Opioid

6 receptor

subtypes

are associated

with different

potassium

Table 1, p. 136, should read: TABLE

1

Antinociceptive Agonist

A,, values

(nmol)

Glyblenclamide Alone

Morphine

DPDPE

Deltorphin

U69.593

HP

(and 95% confidence

II

intervals)

for agonists

acting

(Glyb)

at opioid

receptor

Tetraethylammonium + 40 pg Glyb

Shift ratio

Alone

subtypes

in the mouse tail-flick

test.

(TEA) +4OpgTEA

Shift ratio

1.462 (0.81-2.11)

7.18 (3.77-10.59)

4.9

1.462 (0.81-2.11)

1.373 (0.65-2.09)

0.9

21.319 (15.52.-27.12)

192.93 (9.94-375.91)

9.1

6.2616 (4.72-7.80)

6.313 (4.24-8.39)

1.0

12.235 (9.il-15.36)

10.664 (8.30-13.03)

0.9

4.215 (2.97-5.58)

16.945 (5.89-28.00)

4.0

25.477 (17.68-33.28)

26.60 (17.35-35.85)

1.0

16.512 (9.01-24.01)

18.355 (10.23-26.48)

1.1

20805

Announcement

Eden

(The Netherlands), May 2-3, 1991

The Center for Bio-Pharmaceutical Sciences, is organizing an international course on Drug-Drug and Drug-Food Interactions - Mechanisms, Study Design and Clinical Significance, May 2-3 1991. Leiden, the Netherlands. This course has been designed for pharmacologists, hospital pharmacists, medical doctors and employees of pharmaceutical industry who are involved in clinical drug research and the evaluation of data with a view to registrationinformatiorr please contact: the Course Secretariate, c/o Ms. H.A.H. Nauta, Center for Bio-Pharmaceutical Sciences, P.O. Box 9502. 2300 RA Leiden, The Netherlands. Telephone: 3171274341: Telefax: 3171274277.

Forfurther