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E114 Hypocalciuric and antihypertensive effects of losartan versus hydrochlorothiazide in the hypertensive postmenopausal women
1
ASH XIII ABSTRACTS
2
4
E
A
1
]
1
2A
N 9 4 PH
9
E
E O TV A A AT AR LN T T U HI H A E A YH A P T NR E H E I R I T O E ANN E O T C F O O T FM R A BA L E NI V H DHN C OA L TT N A I PS H P W P F V V EE M O R E J T N A A oO A O N ) AM S oSH P MU u O C c NUI Eh L A RC r P L U A B R u aAn I d d ae s G nf sc i ct a r r B M S A Re aM o s rk i , i Hn Mt Sm wr rs d c u a o li i R e F eC ao P c rF dr hi a om r H eav o aa ad ct n ha oi er a v c p p a t m B T a o t s i t e t a a tv a t rn h at hit i hl u ye hp u i n eh r dr a t i e et v f a e be e o t c o Tf o a rV m n r t i ep r e dp ht naA ma o at i nc a a l rtr n o p t La b t i ap s o r s m m od l t nt i eo uhr c sy oe o( p e rmm s c e a ps e rt r o t Ci tr n nema r e t nn n e s ti S n p ( F 3 M aw ei a u t is s ia & t m3e e nr L nh n e tt t a yi t n h ix e vtn (tl e a el s had etdi werey i i t sp A pn B r atc i tr ut P t n hiu s t > yn h eh d o o ne p v ( i m u E m a ap w p t l w a fr m ei 3 a as n r t hh c e d H i oe e m oo e b r i ug w h r t a y a B < p g a r a i ad b r em ro a d f 6o c ao ak l r e a l un e nu nL i ( l.i v a p neo e cn l l a b M m e t c ( oo 2i T m +V m r1 m n bea t B 2 ni r H h d( nt A h 5a o Ma B 2l p ht S ae 8 g i ap os r d o Am a dl 2 p gog w n i ) o T ( m r o V a S ( me n H d re ap s d d p p s a ye r 4 m ra w L ote O O i mr n r ll u h nDo 2h m e w pv a b a ea a t e l oa t rd ue s f Ha o in b e s m t f g d t d a t L g a b a t p I r c l ni e e1 v A n e t a r sri c tt itili m g n u e ao ev t d r in d d H 1 b f f 6 m e 6 a d ei w ps vw 2 B t m a e 3e C n ul a a wis su am i ba rl r vr i mii o s te e o yn cu at eB l a t a a i t n d r f he i t i m et ew k hi m n l n a e pa r edt i i s yo dr c a ( ma ( o a s T r s t i t 3e g b h d sB e r e h mo h p ua c hwtrh ul a uew m t eP a e ep i a d m ai rd s cp i et t ne r a cm ent osf rl tr 1r i m n p evwb L aaio 1 i a e- l a tm is d w H w c ( ( p n t b c ht b o v Ai om av s ac n p sa a Hk aal Lh aer 9 ( n r d l u 5l i i o eH wso sn n Sy /s ieas as m p i B r rg i t c eno g oN o i nd f ro u i c c/ - o rh at / ac n iu t e t Dm B d u b (i H nn p i r a tw t 3 g f n of t e a r t e erf t o e acco hn e u s d i w n i b g f i i os w c e hs n r c e t e b ft ( 0 e( O p a r a m eOa 6 m r O s . H C ( N ( Changes Pulsewave Camt)d Carol,d,ml,ma MeanSP (mnHg) Il L 2 I1 1 I1 1 M veloc,!y d,sten$,on(%) med,aIhwkness (NW) [..) H 2 ]v f I 9 1 I 1 Ve,apam,l S, (2401Tw) 13+9 .15?18 08+07 004 *008 I ( U ( G ( TrmddaprIl 12i 10 -17*15 00>* 007 06+05 I3 1 L 4 1 I9 (2mg) I I I I I H 4 S 11 1 [ 1 Trmddapc,l(2 ring)+ I 5 VmPm [180rng) 19* 11. 1 8+1 5 ~002?01 08+08 f L 4 4 :H 4 ( 3 c I betweenthe3groups ‘= P. Offi C s a a a h e t H In conclusion, this study s t t c o V oh a me m E h bob wr b pt a a n t ea ei ta hm nw p Lh o la m ah T d r m B at e e o tn m c do r nop o e cp a o aa f pl m r sr p a c io e nl t f t p i oma p p d n rda rb t 3 aro t ei v a e e c m t mf r ei oe t w ti nh f t e e ai s t F rr w b e e u e a x tr s p i m t euo n h s l t l es t . K W K :A ne a tC c i y b gh A a y hwl p e e l o mo a r tn q cr e an n u t dCs i nie svs c a i A n r h t i e b ri ti o e r s .
E
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2D P
M G G c
t I ( m
t
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a a
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A+D n-16
t
a
s
1
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p
l
...
e
161,4*15 .. .
101,4s .. .
14,5*I4 ..
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MF N T
a n
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2
1
6
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p s p
(mgdl):
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1
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3
s w p
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77,3i41
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b
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a
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ASH XIII ABSTRACTS
2
4
E
A
1
]
1
2A
N 9 4 PH
9
E
E O TV A A AT AR LN T T U HI H A E A YH A P T NR E H E I R I T O E ANN E O T C F O O T FM R A BA L E NI V H DHN C OA L TT N A I PS H P W P F V V EE M O R E J T N A A oO A O N ) AM S oSH P MU u O C c NUI Eh L A RC r P L U A B R u aAn I d d ae s G nf sc i ct a r r B M S A Re aM o s rk i , i Hn Mt Sm wr rs d c u a o li i R e F eC ao P c rF dr hi a om r H eav o aa ad ct n ha oi er a v c p p a t m B T a o t s i t e t a a tv a t rn h at hit i hl u ye hp u i n eh r dr a t i e et v f a e be e o t c o Tf o a rV m n r t i ep r e dp ht naA ma o at i nc a a l rtr n o p t La b t i ap s o r s m m od l t nt i eo uhr c sy oe o( p e rmm s c e a ps e rt r o t Ci tr n nema r e t nn n e s ti S n p ( F 3 M aw ei a u t is s ia & t m3e e nr L nh n e tt t a yi t n h ix e vtn (tl e a el s had etdi werey i i t sp A pn B r atc i tr ut P t n hiu s t > yn h eh d o o ne p v ( i m u E m a ap w p t l w a fr m ei 3 a as n r t hh c e d H i oe e m oo e b r i ug w h r t a y a B < p g a r a i ad b r em ro a d f 6o c ao ak l r e a l un e nu nL i ( l.i v a p neo e cn l l a b M m e t c ( oo 2i T m +V m r1 m n bea t B 2 ni r H h d( nt A h 5a o Ma B 2l p ht S ae 8 g i ap os r d o Am a dl 2 p gog w n i ) o T ( m r o V a S ( me n H d re ap s d d p p s a ye r 4 m ra w L ote O O i mr n r ll u h nDo 2h m e w pv a b a ea a t e l oa t rd ue s f Ha o in b e s m t f g d t d a t L g a b a t p I r c l ni e e1 v A n e t a r sri c tt itili m g n u e ao ev t d r in d d H 1 b f f 6 m e 6 a d ei w ps vw 2 B t m a e 3e C n ul a a wis su am i ba rl r vr i mii o s te e o yn cu at eB l a t a a i t n d r f he i t i m et ew k hi m n l n a e pa r edt i i s yo dr c a ( ma ( o a s T r s t i t 3e g b h d sB e r e h mo h p ua c hwtrh ul a uew m t eP a e ep i a d m ai rd s cp i et t ne r a cm ent osf rl tr 1r i m n p evwb L aaio 1 i a e- l a tm is d w H w c ( ( p n t b c ht b o v Ai om av s ac n p sa a Hk aal Lh aer 9 ( n r d l u 5l i i o eH wso sn n Sy /s ieas as m p i B r rg i t c eno g oN o i nd f ro u i c c/ - o rh at / ac n iu t e t Dm B d u b (i H nn p i r a tw t 3 g f n of t e a r t e erf t o e acco hn e u s d i w n i b g f i i os w c e hs n r c e t e b ft ( 0 e( O p a r a m eOa 6 m r O s . H C ( N ( Changes Pulsewave Camt)d Carol,d,ml,ma MeanSP (mnHg) Il L 2 I1 1 I1 1 M veloc,!y d,sten$,on(%) med,aIhwkness (NW) [..) H 2 ]v f I 9 1 I 1 Ve,apam,l S, (2401Tw) 13+9 .15?18 08+07 004 *008 I ( U ( G ( TrmddaprIl 12i 10 -17*15 00>* 007 06+05 I3 1 L 4 1 I9 (2mg) I I I I I H 4 S 11 1 [ 1 Trmddapc,l(2 ring)+ I 5 VmPm [180rng) 19* 11. 1 8+1 5 ~002?01 08+08 f L 4 4 :H 4 ( 3 c I betweenthe3groups ‘= P. Offi C s a a a h e t H In conclusion, this study s t t c o V oh a me m E h bob wr b pt a a n t ea ei ta hm nw p Lh o la m ah T d r m B at e e o tn m c do r nop o e cp a o aa f pl m r sr p a c io e nl t f t p i oma p p d n rda rb t 3 aro t ei v a e e c m t mf r ei oe t w ti nh f t e e ai s t F rr w b e e u e a x tr s p i m t euo n h s l t l es t . K W K :A ne a tC c i y b gh A a y hwl p e e l o mo a r tn q cr e an n u t dCs i nie svs c a i A n r h t i e b ri ti o e r s .
E
E A D
V T
F
A N U
A
P
T
2D P
M G G c
t I ( m
t
e
r A a 1 d g
(
A t r
w
u d b
a a
s g
A+D n-16
t
a
s
1
1
p
l
...
e
161,4*15 .. .
101,4s .. .
14,5*I4 ..
na,eta
63,1*4
128,2*I6
K
1 s v m
t
1
/ 1 d c t t t c
a d
M
P
MF N T
a n
i
e
t
c-LDL
n
i
(
2
1
6
1
ZW,afxl
R 8 (
p s p
(mgdl):
31,7*’Z9
A: 39,4~12
/
1
/
( w w
A c
a a
3
s w p
d r
77,3i41
I 144,6+12
p
e 2 d
-
5
I 1=,4*14 ..
217*22
a
(JAE
(
2
m D
S n4 a s t o i o o a p p w m w a am r p t i I ( a 8 m w ( m a p a o 8w l t s b p w s f p f a a r s
b
(
(’) P<0,05: (M) P< 0,01; (“m) p< 0,001. -HDL 42,3*1O A+ D:41,9*1O / 45,3*12. Triglycerides
s ( C m m ah
a
F EA L I I l EL W I I R aE
s
Cholas.
(
1
W
G T e 5 h
O T A Pk T Y H ETP
r Glue-e
..
a
w m ( a l r
A S F T AO I W H A
a m d d t T d c a t T c s d t t b
*7 H a a1 r
r
w n a b
BP (mmHg) Systolic Diastolic
Tfl.
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t c
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P p a H w c t 5 r b s l U r D c Unlike atcnolol, t p s d p r e w s a t a e r m r a e w h c c f b T m i w c na m m h a r b p t w c
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