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Edible native plants of the Rocky Mountains
The molecular weights of most proteins were estimated by chromatography on Sephadex G-50 to lie between 10,000 and 25,000. Fractions 1, 11, and 12 also contained substances larger than 25,000 . Fraction 9, the most toxic fraction, consisted mainly of proteins smaller than 10,000 . Fraction 2 contained only nucleotides. Fraction 10, in which none of the assayed activities were found, was highly purified. It gave one peak in gel filtration and one sharp band and a weak line (traces of contaminants) in polyacrylamide gel electrophoresis. Other fractions contained more contaminants . E.K . HwxtuNaTOr+, H. D. (Colorado State University, Fort Collies, Colorado, U.S .A.) . Edible Native Plants of the Rocky Mountains. University of New Mexico Press, 392 pp., 1967 .
'fats weu. written text on the plants of the Rocky Mountain area of the United States is divided into nine sections, including a forty-five page chapter on poisonous plants . Each plant is listed, described and illustrated according to its botanical species. The illustrations are excellent and the text is written in a clear, concise and interesting manner. Of particular interest to this reviewer is the space given to ethnobotanical data, particularly on the use of these plants by the historic and prehistoric Indians of the area. The text has an excellent bibliography and a very usable index. The adventurous reader will also wet his palate on the exotic taste sensations and interesting gourmet experiences described by the author . F.E .R . Tonn.ttvsotv, J. C. and J.+~s, T. N. (Section on Cardiovascular Research, Henry Ford Hospital, Detroit, Michigan, U.S.A.). Pharmacologie actions of tetrodotoxin studied by direct perfusion of the sinus node . Circulation Res. 23, 501, 1968.
DtaFCr cardiac effects of tetrodotoxin (TTX) on thesinus node in situ and its normally preserved inmervation were investigated by direct perfusion of the canine sinus node through its own artery . TTX (10-e-10- ' wg per ml) had no direct chronotropic effect and did not affect chronotropic responses to stellate or vagal stimulations . Immediate sinus slowing occurred following a 1~0 Pg per ml dose which reached its maximum 2 to 6 min after the injection ; this negative chronotropic effect lasted 12 to 60 min and was not prevented by a vagal blocking intranodal dose of atropine. This same TTX concentration produced an immediate blockade of vagal response and a less profound blockade of the response to stellate stimulation . These blockades generally lasted as long as the negative chronotropic effect . Although TTX produced adrenergic and cholinergic neural blockade, it did not affect the nodal response to direct perfusion of either acetylcholine or norepinephrine. M.E .B . Hot-t.~t~n, W. J. 77re Moth Book. New York : Dover Publications, 479 pp ., 1968.
Trns is another of Dover's well done, unabridged, republications of an indispensable reference work of the past . Originally published in 1903, Moth Book was a standard text for many years. It was subsequently updated by several scholars, one of whom was A. E. Brower, who wrote the Foreword to thepresent edition. Brower has also added footnotes to the republication, which deal for the most part with misidentifications . The reproductions of the 48 colored plates and 1400 illustrations are quite well done . This paperback is modestly priced at 15 .00. F.E .R. Gttvstu=xo, N. J., Dnuety M. and St .oTrn, K. (University of Miami, Miami, Fla, U.S .A .) . Melittin used as a protective agent against X-irradiation. Nature, Lord. 220, 1334, 1968 .
Mstrrrnv, the chiefcomponent of bee venom, in a dose of 5 mg per kg protected 100 per cent of mice against a dose of X-irradiation causing 40 to 50 per cent mortality in controls . Whole bee venom in comparable dose gave questionable protection . Melittin is a basic polypeptide whose structure is comparable with that of a detergent, a fact that may account for its radioprotective effect . S.A .M .
'fats weu. written text on the plants of the Rocky Mountain area of the United States is divided into nine sections, including a forty-five page chapter on poisonous plants . Each plant is listed, described and illustrated according to its botanical species. The illustrations are excellent and the text is written in a clear, concise and interesting manner. Of particular interest to this reviewer is the space given to ethnobotanical data, particularly on the use of these plants by the historic and prehistoric Indians of the area. The text has an excellent bibliography and a very usable index. The adventurous reader will also wet his palate on the exotic taste sensations and interesting gourmet experiences described by the author . F.E .R . Tonn.ttvsotv, J. C. and J.+~s, T. N. (Section on Cardiovascular Research, Henry Ford Hospital, Detroit, Michigan, U.S.A.). Pharmacologie actions of tetrodotoxin studied by direct perfusion of the sinus node . Circulation Res. 23, 501, 1968.
DtaFCr cardiac effects of tetrodotoxin (TTX) on thesinus node in situ and its normally preserved inmervation were investigated by direct perfusion of the canine sinus node through its own artery . TTX (10-e-10- ' wg per ml) had no direct chronotropic effect and did not affect chronotropic responses to stellate or vagal stimulations . Immediate sinus slowing occurred following a 1~0 Pg per ml dose which reached its maximum 2 to 6 min after the injection ; this negative chronotropic effect lasted 12 to 60 min and was not prevented by a vagal blocking intranodal dose of atropine. This same TTX concentration produced an immediate blockade of vagal response and a less profound blockade of the response to stellate stimulation . These blockades generally lasted as long as the negative chronotropic effect . Although TTX produced adrenergic and cholinergic neural blockade, it did not affect the nodal response to direct perfusion of either acetylcholine or norepinephrine. M.E .B . Hot-t.~t~n, W. J. 77re Moth Book. New York : Dover Publications, 479 pp ., 1968.
Trns is another of Dover's well done, unabridged, republications of an indispensable reference work of the past . Originally published in 1903, Moth Book was a standard text for many years. It was subsequently updated by several scholars, one of whom was A. E. Brower, who wrote the Foreword to thepresent edition. Brower has also added footnotes to the republication, which deal for the most part with misidentifications . The reproductions of the 48 colored plates and 1400 illustrations are quite well done . This paperback is modestly priced at 15 .00. F.E .R. Gttvstu=xo, N. J., Dnuety M. and St .oTrn, K. (University of Miami, Miami, Fla, U.S .A .) . Melittin used as a protective agent against X-irradiation. Nature, Lord. 220, 1334, 1968 .
Mstrrrnv, the chiefcomponent of bee venom, in a dose of 5 mg per kg protected 100 per cent of mice against a dose of X-irradiation causing 40 to 50 per cent mortality in controls . Whole bee venom in comparable dose gave questionable protection . Melittin is a basic polypeptide whose structure is comparable with that of a detergent, a fact that may account for its radioprotective effect . S.A .M .