Editorial Introduction On June 9 1986 Hazleton Biotechnologies and Hazleton Laboratories Europe organized a meeting on genotoxicity produced in cultured mammalian cell assays by treatment conditions. This meeting focused on treatment conditions in in vitro testing, which if not adequately controlled, may lead to false positive results. The findings reported at that symposium are of considerable importance to all workers involved in genotoxicity testing or evaluating results of such assays. They should reach as wide an audience as possible, and thus I am happy that these papers and a few related ones are now appearing as a special issue of the section on Genetic Toxicology Testing of Mutation Research. Leiden May 1987