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EEG findings in anorexia nervosa
$153 was shown to mirror the asymmetry of sensory thresholds. Thus, there is evidence of lateralization of somatosensory function which has to be considered in regard to other laterality measures.
P23.12 DO THE RIGHT AND LEFT H I P P O C A M P I INDEPENDENTLY D I S T I N G U I S H MUSICAL C O N S O N A N C E S AND DISSONANCES?
bursts in 8. Small spikes which were observed most frequently in the abnormal EEG predominantly appeared in the occipital area. Generalized slow activity appeared in the bulimia and compulsive types. Small spikes were observed at the same frequency in three types. 14 a n d / o r 6 Hz positive spike predominantly appeared in anorexia type. The appearance of small spikes in the occipital area suggests the involvement of limbic system, the function of which is the regulation of autonomic nervous system and emotional controls.
tt.G. Wwser and G. Mazzola
(ZiJrich, Switzerland) Our study sought to determine whether, where and how the consonances or dissonances of musical intervals might be reflected in the electrical activity (depth-EEG) of the human brain. An adequate musical test programme was presented to a 35-year old male during pre-surgical evaluation for resective surgical epilepsy therapy, who had depth electrodes implanted within lhe planum temporale (near Heschl's gyrus) and the hippocampal formations of both sides. Of the 170 musical events (duration 0,6-1,5 sec) the greater part consisted of intervah,, either isolated from each other or in a suitable musical context. Analysis of the EEG response was based on the standard Fourier power spectrum taken throughout the duration of a musical event and 'spectral vigilance vectors' were calculated. In testing spectral vigilance with respect to isolated musical intervals, we found that numerical vigilance values of the left hippocampus reflected precisely the classical consonance-dissonance dichotomy (according to Palestrina). The average vigilance for dissonances was twice as large as that for consonances. The function y = 5x + 2 which transforms the classical consonances (semitones 0, 3, 4, 7, 8, 9) into dissonances (1, 2, 5, 6, 10, 11) is reflected by the activity of the left, and the other function with very distinct properties in mathematical music theory, i.e. y - l l x + 5 , is reflected by the activity of the right hippocampus.
P23.13 EEG F I N D I N G S IN ANOREXIA NERVOSA.
EXPERIMENTAL M O D E L S OF ELECTROPHYSIOLOGICAL PHENOMENA. P24.01 ELECTROENCEPHALOGRAPHIC STUDY OF EXPERIMENTAL BRAIN T U M O U R IN RAT. J. Suzuki, T. Kamijyo and K. Munekata
(Tokyo, Japan) The electroencephalograms of rats with an experimental brain turnout were investigated to elucidate the mechanisms of occurrence of abnormal electrical activities. Glioma cells (Fischer 344-9LK, 105/~tl × 10ml) were transplanted into the right frontal motor cortex of 17 Fischer male rats. All the rats were divided into 2 groups. Eight rats of the 1st group were sacrificed between :he 3rd and 15th day of the transplantation of the tumour cells. Sizes of the transplanted tumours were measured in brain slices stained with H-E staining. Nine of the other group were implanted with concentric electrodes at the right and left motor, right frontal and right somatosensory cortices, the right and left VPL and centromedian thalamic nuclei (CM) and the right and left hippocampi 10 days before the transplantation of the cells. The areas of the tumours in a frontal section grew logarithmically. The amplitude of the ECoG in the right and left motor cortices increased once around the 7th day, but decreased around the 12th day. The power spectrum of the ECoG demonstrated similar features. In most cases spike activities were observed in the CM a n d / o r VPL from the 5th day at the earliest and in the right cortices.
T. Nozawa, T. Akama, I. Homma and M. Ebe
(Tokyo, Japan) 54 EEGs of 39 patients with anorexia nervosa, (all females: 11 to 38 years of age), were studied. 10 of 39 patients ran the course of bulimia (bulimia type) and 6 of them ran the course of compulsive eating (compulsive type). The other patients took only the course of a n o r e x i a (anorexia type). Of 54 EEGs, normal records were obtained in 9(17%), borderline in 8(14%) and abnormal in 37(69%). The abnormal EEG findings were: generalized slow activity in 5, small spikes in 19, sharp waves in 3, spike and wave complex burst in 1, 14, a n d / o r 6 Hz, positive spike in 12, 6 Hz phantom spike-and-wave in 3 and slow wave
P24.02 A C E T Y L C H O L I N E EFFECTS ON SYNAPTICALLY-EVOKED VISUAL R E S P O N S E S IN AN ISOLATED BRAIN PREPARATION. C. Berti, G. Khan and Andrea Nistri
(London, UK) Acetylcholine (ACh) is thought to be the excitatory neurotransmitter of the optic nerve in many vertebrate species. We characterised the pharmacological actions of ACh on synaptic transmission in the frog optic tectum. We used an isolated whole brain preparation viable under in vitro controlled condi-
P23.12 DO THE RIGHT AND LEFT H I P P O C A M P I INDEPENDENTLY D I S T I N G U I S H MUSICAL C O N S O N A N C E S AND DISSONANCES?
bursts in 8. Small spikes which were observed most frequently in the abnormal EEG predominantly appeared in the occipital area. Generalized slow activity appeared in the bulimia and compulsive types. Small spikes were observed at the same frequency in three types. 14 a n d / o r 6 Hz positive spike predominantly appeared in anorexia type. The appearance of small spikes in the occipital area suggests the involvement of limbic system, the function of which is the regulation of autonomic nervous system and emotional controls.
tt.G. Wwser and G. Mazzola
(ZiJrich, Switzerland) Our study sought to determine whether, where and how the consonances or dissonances of musical intervals might be reflected in the electrical activity (depth-EEG) of the human brain. An adequate musical test programme was presented to a 35-year old male during pre-surgical evaluation for resective surgical epilepsy therapy, who had depth electrodes implanted within lhe planum temporale (near Heschl's gyrus) and the hippocampal formations of both sides. Of the 170 musical events (duration 0,6-1,5 sec) the greater part consisted of intervah,, either isolated from each other or in a suitable musical context. Analysis of the EEG response was based on the standard Fourier power spectrum taken throughout the duration of a musical event and 'spectral vigilance vectors' were calculated. In testing spectral vigilance with respect to isolated musical intervals, we found that numerical vigilance values of the left hippocampus reflected precisely the classical consonance-dissonance dichotomy (according to Palestrina). The average vigilance for dissonances was twice as large as that for consonances. The function y = 5x + 2 which transforms the classical consonances (semitones 0, 3, 4, 7, 8, 9) into dissonances (1, 2, 5, 6, 10, 11) is reflected by the activity of the left, and the other function with very distinct properties in mathematical music theory, i.e. y - l l x + 5 , is reflected by the activity of the right hippocampus.
P23.13 EEG F I N D I N G S IN ANOREXIA NERVOSA.
EXPERIMENTAL M O D E L S OF ELECTROPHYSIOLOGICAL PHENOMENA. P24.01 ELECTROENCEPHALOGRAPHIC STUDY OF EXPERIMENTAL BRAIN T U M O U R IN RAT. J. Suzuki, T. Kamijyo and K. Munekata
(Tokyo, Japan) The electroencephalograms of rats with an experimental brain turnout were investigated to elucidate the mechanisms of occurrence of abnormal electrical activities. Glioma cells (Fischer 344-9LK, 105/~tl × 10ml) were transplanted into the right frontal motor cortex of 17 Fischer male rats. All the rats were divided into 2 groups. Eight rats of the 1st group were sacrificed between :he 3rd and 15th day of the transplantation of the tumour cells. Sizes of the transplanted tumours were measured in brain slices stained with H-E staining. Nine of the other group were implanted with concentric electrodes at the right and left motor, right frontal and right somatosensory cortices, the right and left VPL and centromedian thalamic nuclei (CM) and the right and left hippocampi 10 days before the transplantation of the cells. The areas of the tumours in a frontal section grew logarithmically. The amplitude of the ECoG in the right and left motor cortices increased once around the 7th day, but decreased around the 12th day. The power spectrum of the ECoG demonstrated similar features. In most cases spike activities were observed in the CM a n d / o r VPL from the 5th day at the earliest and in the right cortices.
T. Nozawa, T. Akama, I. Homma and M. Ebe
(Tokyo, Japan) 54 EEGs of 39 patients with anorexia nervosa, (all females: 11 to 38 years of age), were studied. 10 of 39 patients ran the course of bulimia (bulimia type) and 6 of them ran the course of compulsive eating (compulsive type). The other patients took only the course of a n o r e x i a (anorexia type). Of 54 EEGs, normal records were obtained in 9(17%), borderline in 8(14%) and abnormal in 37(69%). The abnormal EEG findings were: generalized slow activity in 5, small spikes in 19, sharp waves in 3, spike and wave complex burst in 1, 14, a n d / o r 6 Hz, positive spike in 12, 6 Hz phantom spike-and-wave in 3 and slow wave
P24.02 A C E T Y L C H O L I N E EFFECTS ON SYNAPTICALLY-EVOKED VISUAL R E S P O N S E S IN AN ISOLATED BRAIN PREPARATION. C. Berti, G. Khan and Andrea Nistri
(London, UK) Acetylcholine (ACh) is thought to be the excitatory neurotransmitter of the optic nerve in many vertebrate species. We characterised the pharmacological actions of ACh on synaptic transmission in the frog optic tectum. We used an isolated whole brain preparation viable under in vitro controlled condi-