Effect of autonomic blockade on Doppler indices of diastolic filling

Effect of autonomic blockade on Doppler indices of diastolic filling

162A ABILITY CF RAGNETICRBSONAtlCE UfAGWG STUNNEDPACM INFARCTEDPIYUCARDIUN FULL EXPERIMENTALISQEMIA of Cardiology, IndianapolL, JACC Vol. 15, No. ...

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162A

ABILITY CF RAGNETICRBSONAtlCE UfAGWG STUNNEDPACM INFARCTEDPIYUCARDIUN FULL

EXPERIMENTALISQEMIA

of Cardiology, IndianapolL,

JACC Vol. 15, No. 2 February 1990:162A

ABSTRACTS

Robert D. Tarter, en G. Sawada, MD Erannert Institute dicine, Indiana University School of IN

LL ARTERIAL NETIC

MEASUREMENT OF BLOODFLOW WELOCI VESSELS: IN VIVO WALIDAT~O~ OF RESONANCEIMAGINGTECl!NIQUES

Medicine,Houston,TX. Adequatenoninvasive assessmentof bloodflo deeplylocatedvesselsis not currentlyfeas

abdominalaortain 9 rabbits

.

dY+BfUnotiOnti aCyOotwdS~B. Inoreased SI 18

irruveraibly

injured tissue. The axtent of the m~hon eventual 8 with, but w8r8atim&ea infarot size.

ACCURATEPREOPERATIVE DIAGNOSIS OF PERICARDIAL CONSTRI USING C TOEOG Ron H. Stanford, , nsJ, RD, Hal C, Pa0 ullo, RD, lvin L narcur, RD, FACC. Univ8raity Of Iowa, Iowa City, XA

The aorticdi ter averaged2.61mm (range1.753.75 mm). The NMR velocitysoectraa~reo~oualitativolw with the Dopplervelocityprofilesana predictions.The velocities measuredby Doppler ultrasound(range-3.44-77.3 cm/s) axi NM e -6.2480.8 cm/s)were sir:TAr(rmO.94). These dicate that NMR techniques providean accuraten ive assessment of bloodflow velocitiesin sm eDly locatedvessels.

EFFECT OF AWTONONIC BLOCKADE ON DOPPLERINDICES OF DIASTOLIC FILLING Gary D. Plotnick, M.D., F.A.C.C., John S. Cottdienet,

Previ rly tre locity (A), and i8ovolumic relaxation (IRT) in response to chaqes in loading conditions. To assessthe influence of autonomic reflexes, 2-D and Doppler echophonocardiogaphy was performed in 8 normal rubjects before and during autonomic blockade (propranolal 0.2 u&kg IV nd atropine 0.04 q/kg IV) in the supine (SUP), passive upright 80° tilt (TILT), and passive leg raised (ELEV) positions and during supine isometric exsrcise (ISO). Heart rat8 (RR), systolic blood pressure (SBP), and left ventriculer end-diastolic dimension (EDD) were obtained. Supine values are given below. *P
During

urgical evidence of : Cine CT provides ic and physiologic data which allow accurate preoperative diagnosis of pertcardial constrfction.

53 79*

SBP

EDD

119 131*

5.2 5.2

IRT .68 .54*

.34 .45*

2.0 1.2*

65 74+

With TILT: Autonomic blockade did not alter the decrease in EDD, E, A and E/A or the increase in IRT despite blocking the increase in RR. With ELEV: autonomic block8g8 was associated with increase in EDD and h not seen before blockade. With ISO: autonomic blockade blocked the increase in RR, SBP, and IRT but did not alter the decrease in E and E/A, We conclude autonomic blockade significantly modifies both hemodynamic response and Doppler indices of diastolic filling and may allow better understanding of the relationship of loading conditions and Doppler diastolic indices.