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EFFECT OF SCLEROTHERAPY USING COPPER WIRES ASSOCIATED WITH CORTICOSTEROIDS IN THE TREATMENT OF VASCULAR LESIONS
OOOO Volume 129, Number 1 should be included: (1) a clear definition for CMI; (2) a temporal association, (3) a record of all types of CMI, including dental, prosthetic, and functional; and (4) a notation of tumor size. Based on previously published CMI criteria, 5 cases of oral mucosal carcinomas T1 and T2 are presented. In each of them, the methodology to outline clinically the presence of CMI is shown, and compliance with the proposed CMI criteria is analyzed in detail.
HUMAN PAPILLOMA VIRUS ASSOCIATED ORAL EPITHELIAL DYSPLASIA: A SERIES OF CASES WITH CLINICAL FEATURES. RENE PANICO, EDUARDO PIEMONTE, ANGEL TALAVERA and, GERARDO GILLIGAN Human papilloma virus (HPV) could be found in oral potentially malignant disorders (OPMD) with multiple clinical presentations. However, there are dysplastic intraepithelial lesions associated with HPV harboring histopathologic findings that should be differentiated from classic epithelial dysplasias. The aim of this study is to present a series of cases of HPV-associated oral epithelial dysplasia, highlighting the role of local factors. Age, gender, location site, tobacco use, alcohol habit, chief complaint, clinical presentation, chronic mechanical irritation, degree of epithelial dysplasia, and polymerase chain reaction (PCR)-HPV genotype were recorded. Further research is needed to address clinical aspects of HPV epithelial dysplasia and its prognosis. Oral HPV infection is not similar to cervical infection due to the presence of other factors that could modify the behavior of the virus.
ORAL VERRUCOUS CARCINOMA: A CASE ^ SERIES. ELIS ANGELA BATISTELLA, LILIANE JANETE GRANDO, MARIANA COMPAROTTO MINAMISAKO, EDUARDO MEURER, AIRA BONFIM SANTOS and, ROGERIO GONDAK Oral verrucous carcinoma is an uncommon variant of squamous cell carcinoma, characterized by its exophytic outgrowing clinical aspect. In a single-institution 10-year retrospective analysis (2008-2018), 5 cases of verrucous carcinoma were identified, affecting 2 men and 3 women (mean age = 69.2 y, ranging from 62-80 y). All cases presented as an exophytic verrucous growth on the buccal mucosa, with fibrous consistency to palpation. Four lesions exhibited a sessile insertion, whitish color, not removable by scraping; 1 lesion had a pedicled insertion and brownish color. Histologic sections depicted neoplasia of epithelial origin composed of neoplastic cells arranged in broad ridges, elongated toward the surface, covered by abundant parakeratin. Corneal pearls, nuclear pleomorphism and hyperchromatism, and increased mitosis rate were observed. The dense connective tissue revealed chronic inflammatory infiltrate in all cases. All patients underwent surgical resection and remain under follow-up care.
EFFECT OF SCLEROTHERAPY USING COPPER WIRES ASSOCIATED WITH CORTICOSTEROIDS IN THE TREATMENT OF VASCULAR LESIONS. DOLLY ARISTIZABAL GARCIA, RUBERH ANDRES MERA VERGARA, ALEJANDRO ANGEL ORTIZ, DANIELA BERNAL ROJAS and, DIEGO FERNANDO SANCHEZ HENAO Vascular injuries in the oral cavity cause anesthetic and functional problems, and a high risk of severe hemorrhages in
ABSTRACTS
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simple surgical treatments; therapy with copper wires and corticosteroids generates local coagulation and fibrosis and are effective for an uncomplicated resection. Through a series of cases, clinical and anatomopathologic characteristics of the combined sclerotherapy effects are described, as an alternative for the treatment of vascular malformations performed on 7 patients, using intralesional corticoid (0.2 mL/cm2) for 2 or 3 weeks, followed by a cerclage with copper wires, for 1 week, until color change from red or purple to lighter color and a fibrous consistency was observed. Continued resection of the lesion occurred in the absence of bleeding. Histologic studies were performed, which revealed neoformation of fibrous tissue, hyalinization of blood vessels, and loss of endothelial continuity. The result was favorable in 100% of the cases.
ORAL LESIONS TREATED WITH CRYOSURGERY: MUCOCELE, RANULA, PYOGENIC GRANULOMA, VARICOSITY, HEMANGIOMA AND HERPES SIMPLEX. PAULO DE CAMARGO MORAES, GIULIANA ROCHA LIMA, LARISSA AGATTI, RUBENS GONCALVES ¸ TEIXEIRA, VICTOR ANGELO MARTINS MONTALLI, NEY SOARES DE ARAUJO and, JOSE LUIZ CINTRA JUNQUEIRA The therapeutic use of liquid nitrogen has been used since the 20th century for the treatment of various dermatologic, urologic, gynecologic, and oncologic diseases among others. However, this modality is not widespread in the stomatology specialty. It will be presented with a brief introduction of mechanism of action, equipment, technique, and results obtained in the following oral lesions: salivary gland (mucocele and ranula), reactive lesion (pyogenic granuloma), vascular lesions (varicosities and hemangioma), and viral infection (herpes simplex). Institutional grant from S~ao Leopoldo Mandic Dental School.
CONSERVATIVE TREATMENT OF MEDICATION-RELATED OSTEONECROSIS OF THE JAW (MRONJ): REPORT OF 8 CASES. PAULO DE CAMARGO MORAES, MARCELO SPERANDIO, CAROLINA ALVES DO REIS GATI, VERA CAVALCANTI DE ARAUJO, FABRICIO PASSADOR-SANTOS, DANIELA PRATA TACCHELLI and, VICTOR MONTALLI The 8 cases selected for this presentation include medication-related osteonecrosis of the jaw (MRONJ) treated conservatively: 2 cases of breast cancer metastasis, 3 cases of multiple myeloma, and 3 cases of osteoporosis. Two of them occurred in the implant area and in 1 case, the treatment was concluded with hyperbaric oxygen therapy. In 5 cases, a bisphosphonate was given via intravenous route and 3 cases by oral administration. Only 1 case had a combination of bisphosphonates and monoclonal antibody (denosumab). The time to bone sequestration, formation, and expulsion (varied from 3 mo to 4 y) will be discussed. In all cases, the treatment was performed with topical antiseptics and radiographic and clinical monitoring. In some cases, conservative surgery was needed, whereas in others, the necrotic bone was expelled spontaneously. Institutional grant from S~ao Leopoldo Mandic Dental School.
HUMAN PAPILLOMA VIRUS ASSOCIATED ORAL EPITHELIAL DYSPLASIA: A SERIES OF CASES WITH CLINICAL FEATURES. RENE PANICO, EDUARDO PIEMONTE, ANGEL TALAVERA and, GERARDO GILLIGAN Human papilloma virus (HPV) could be found in oral potentially malignant disorders (OPMD) with multiple clinical presentations. However, there are dysplastic intraepithelial lesions associated with HPV harboring histopathologic findings that should be differentiated from classic epithelial dysplasias. The aim of this study is to present a series of cases of HPV-associated oral epithelial dysplasia, highlighting the role of local factors. Age, gender, location site, tobacco use, alcohol habit, chief complaint, clinical presentation, chronic mechanical irritation, degree of epithelial dysplasia, and polymerase chain reaction (PCR)-HPV genotype were recorded. Further research is needed to address clinical aspects of HPV epithelial dysplasia and its prognosis. Oral HPV infection is not similar to cervical infection due to the presence of other factors that could modify the behavior of the virus.
ORAL VERRUCOUS CARCINOMA: A CASE ^ SERIES. ELIS ANGELA BATISTELLA, LILIANE JANETE GRANDO, MARIANA COMPAROTTO MINAMISAKO, EDUARDO MEURER, AIRA BONFIM SANTOS and, ROGERIO GONDAK Oral verrucous carcinoma is an uncommon variant of squamous cell carcinoma, characterized by its exophytic outgrowing clinical aspect. In a single-institution 10-year retrospective analysis (2008-2018), 5 cases of verrucous carcinoma were identified, affecting 2 men and 3 women (mean age = 69.2 y, ranging from 62-80 y). All cases presented as an exophytic verrucous growth on the buccal mucosa, with fibrous consistency to palpation. Four lesions exhibited a sessile insertion, whitish color, not removable by scraping; 1 lesion had a pedicled insertion and brownish color. Histologic sections depicted neoplasia of epithelial origin composed of neoplastic cells arranged in broad ridges, elongated toward the surface, covered by abundant parakeratin. Corneal pearls, nuclear pleomorphism and hyperchromatism, and increased mitosis rate were observed. The dense connective tissue revealed chronic inflammatory infiltrate in all cases. All patients underwent surgical resection and remain under follow-up care.
EFFECT OF SCLEROTHERAPY USING COPPER WIRES ASSOCIATED WITH CORTICOSTEROIDS IN THE TREATMENT OF VASCULAR LESIONS. DOLLY ARISTIZABAL GARCIA, RUBERH ANDRES MERA VERGARA, ALEJANDRO ANGEL ORTIZ, DANIELA BERNAL ROJAS and, DIEGO FERNANDO SANCHEZ HENAO Vascular injuries in the oral cavity cause anesthetic and functional problems, and a high risk of severe hemorrhages in
ABSTRACTS
e39
simple surgical treatments; therapy with copper wires and corticosteroids generates local coagulation and fibrosis and are effective for an uncomplicated resection. Through a series of cases, clinical and anatomopathologic characteristics of the combined sclerotherapy effects are described, as an alternative for the treatment of vascular malformations performed on 7 patients, using intralesional corticoid (0.2 mL/cm2) for 2 or 3 weeks, followed by a cerclage with copper wires, for 1 week, until color change from red or purple to lighter color and a fibrous consistency was observed. Continued resection of the lesion occurred in the absence of bleeding. Histologic studies were performed, which revealed neoformation of fibrous tissue, hyalinization of blood vessels, and loss of endothelial continuity. The result was favorable in 100% of the cases.
ORAL LESIONS TREATED WITH CRYOSURGERY: MUCOCELE, RANULA, PYOGENIC GRANULOMA, VARICOSITY, HEMANGIOMA AND HERPES SIMPLEX. PAULO DE CAMARGO MORAES, GIULIANA ROCHA LIMA, LARISSA AGATTI, RUBENS GONCALVES ¸ TEIXEIRA, VICTOR ANGELO MARTINS MONTALLI, NEY SOARES DE ARAUJO and, JOSE LUIZ CINTRA JUNQUEIRA The therapeutic use of liquid nitrogen has been used since the 20th century for the treatment of various dermatologic, urologic, gynecologic, and oncologic diseases among others. However, this modality is not widespread in the stomatology specialty. It will be presented with a brief introduction of mechanism of action, equipment, technique, and results obtained in the following oral lesions: salivary gland (mucocele and ranula), reactive lesion (pyogenic granuloma), vascular lesions (varicosities and hemangioma), and viral infection (herpes simplex). Institutional grant from S~ao Leopoldo Mandic Dental School.
CONSERVATIVE TREATMENT OF MEDICATION-RELATED OSTEONECROSIS OF THE JAW (MRONJ): REPORT OF 8 CASES. PAULO DE CAMARGO MORAES, MARCELO SPERANDIO, CAROLINA ALVES DO REIS GATI, VERA CAVALCANTI DE ARAUJO, FABRICIO PASSADOR-SANTOS, DANIELA PRATA TACCHELLI and, VICTOR MONTALLI The 8 cases selected for this presentation include medication-related osteonecrosis of the jaw (MRONJ) treated conservatively: 2 cases of breast cancer metastasis, 3 cases of multiple myeloma, and 3 cases of osteoporosis. Two of them occurred in the implant area and in 1 case, the treatment was concluded with hyperbaric oxygen therapy. In 5 cases, a bisphosphonate was given via intravenous route and 3 cases by oral administration. Only 1 case had a combination of bisphosphonates and monoclonal antibody (denosumab). The time to bone sequestration, formation, and expulsion (varied from 3 mo to 4 y) will be discussed. In all cases, the treatment was performed with topical antiseptics and radiographic and clinical monitoring. In some cases, conservative surgery was needed, whereas in others, the necrotic bone was expelled spontaneously. Institutional grant from S~ao Leopoldo Mandic Dental School.