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Efficacy of individualized music-based audiotherapy on depressive disorders – Results of a prospective controlled clinical trial
Abstracts / European Journal of Integrative Medicine 7S (2015) 1–53
Efficacy of individualized music-based audiotherapy on depressive disorders – Results of a prospective controlled clinical trial Vera Brandes ∗ , Darcey D. Terris, Claudia Fischer, Adrian Loerbroks, Marc N. Jarczok, Gernot Ottowitz, Georg Titscher, Joachim E. Fischer Paracelsus Medical University, Research Program for Music – Medicine, Waehringer Strasse 115/19, Vienna 1180, Austria E-mail address: [email protected] (V. Brandes). Introduction: Music therapy enjoys a growing interest from neurobiological research. Different music triggers different activation patterns in depressed patients than in healthy controls. Current treatment options have similar response rates, with mostly symptom reduction, but not complete remission. Low compliance and high dropout rates emphasize the need for alternative or add-on therapies. We evaluated a novel form of receptive music therapy which can be easily administered to out-patients. Methods: Enrolled subjects (n = 203, average age 49.6 ± 13.1 years, 28.1% male) were randomized into four arms: Musictherapy 1 (MT1), Musictherapy 2 (MT2), Placebo (nature sounds) and waiting-list control. Subjects listened for 30 min, twice daily. Multivariate linear regression models assessed depressive symptom changes over five weeks, based on a composite scale (COMP) and the Hamilton Rating Scale for Depression (HAM-D), Beck Depression Inventory (BDI) and Hospital Anxiety and Depression Scale (HADS-D) alone. Results: On average, a significant, positive change in COMP was observed for MT1 (β = 1.44, p = 0.030), but not for MT2 (β = 1.14, p = 0.059) or Placebo (β = 0.57, p = 0.397). After 15 weeks, study participation was associated with a mean HAM-D score reduction of 60% for 89.1% of the compliant probands. Conclusions: This newly developed form of music-based audio therapy is associated with reduced depressive symptoms and high treatment compliance and offers new treatment options for patients with the need for additional therapy or requiring an alternative approach. http://dx.doi.org/10.1016/j.eujim.2015.09.013 Exploring the experience and impact of therapeutic touch treatments to nurse colleagues Amanda Bulette Coakley Massachusetts General Hospital, USA E-mail address: [email protected]. Introduction: Therapeutic touch (TT) reduces anxiety, stress and improves comfort and wellbeing. Providers and recipients of TT benefit from treatments. Nurses provide care which is
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physically and emotionally demanding. The research question was ‘what is the experience and impact of providing and receiving therapeutic touch treatments on nurses?’ The hypothesis was that participants, who receive and offer TT interventions, will have significantly lower cortisol levels, decreased blood pressure and reduced anxiety levels, and significantly improved comfort and well-being. The specific aims were: (1) To test the efficacy of a TT influencing stress, sense of comfort and well-being by: (a) Comparison of physiologic stress markers of cortisol, blood pressure levels and state anxiety levels (STAI) of nurses offering and receiving TT. (b) Comparison of comfort and wellbeing as measured with visual analog scales. (2) To qualitatively understand the experiences of nurses providing and receiving therapeutic touch (TT). Methods: Nurses provided TT treatments to colleagues. Before and after each treatment vital signs; visual analog scales for comfort and wellbeing; state anxiety survey (STAI); and oral cortisol levels were collected. Staff attended focus groups analysis: quantitative data was analyzed through a series of paired t-tests. Results: VAS for comfort, well being and STAI total was statistically significantly improved for TT providers and receivers. Focus group data was analyzed using content analysis. Three themes were identified: (1) TT promoted healing, comfort, and relaxation for nurses. (2) Challenges related to centering, scheduling time, and a busy environment. (3) Nurses identified the benefits of TT for their patients and colleagues. http://dx.doi.org/10.1016/j.eujim.2015.09.014 Randomized controlled trial of yoga and meditation for menopausal symptoms in breast cancer survivors Holger Cramer ∗ , Sybille Rabilber, Romy Lauche, Sherko Kümmel, Gustav Dobos University of Duisburg-Essen, Faculty of Medicine, Department of Internal and Integrative Medicine, Kliniken Essen-Mitte, Klinik für Naturheilkunde und Integrative Medizin, Kliniken Essen-Mitte, Knappschafts-Krankenhaus, Am Deimelsberg 34a, Essen 45276, Germany E-mail address: [email protected]. Introduction: Treatment options for menopausal symptoms in breast cancer survivors remain very limited. The purpose of this trial was to evaluate the effects of a 12-week traditional hatha yoga and meditation intervention on menopausal symptoms in breast cancer survivors. Methods: Patients were randomly assigned to a 12-weeks yoga and meditation intervention or usual care. Primary outcome measure was total menopausal symptoms (Menopause Rating Scale [MRS] total score). Secondary outcome measures included MRS subscales, cancer-specific quality of life (Functional Assessment of Cancer Therapy – Breast), fatigue (Functional Assessment of Chronic Illness Therapy – Fatigue),
Efficacy of individualized music-based audiotherapy on depressive disorders – Results of a prospective controlled clinical trial Vera Brandes ∗ , Darcey D. Terris, Claudia Fischer, Adrian Loerbroks, Marc N. Jarczok, Gernot Ottowitz, Georg Titscher, Joachim E. Fischer Paracelsus Medical University, Research Program for Music – Medicine, Waehringer Strasse 115/19, Vienna 1180, Austria E-mail address: [email protected] (V. Brandes). Introduction: Music therapy enjoys a growing interest from neurobiological research. Different music triggers different activation patterns in depressed patients than in healthy controls. Current treatment options have similar response rates, with mostly symptom reduction, but not complete remission. Low compliance and high dropout rates emphasize the need for alternative or add-on therapies. We evaluated a novel form of receptive music therapy which can be easily administered to out-patients. Methods: Enrolled subjects (n = 203, average age 49.6 ± 13.1 years, 28.1% male) were randomized into four arms: Musictherapy 1 (MT1), Musictherapy 2 (MT2), Placebo (nature sounds) and waiting-list control. Subjects listened for 30 min, twice daily. Multivariate linear regression models assessed depressive symptom changes over five weeks, based on a composite scale (COMP) and the Hamilton Rating Scale for Depression (HAM-D), Beck Depression Inventory (BDI) and Hospital Anxiety and Depression Scale (HADS-D) alone. Results: On average, a significant, positive change in COMP was observed for MT1 (β = 1.44, p = 0.030), but not for MT2 (β = 1.14, p = 0.059) or Placebo (β = 0.57, p = 0.397). After 15 weeks, study participation was associated with a mean HAM-D score reduction of 60% for 89.1% of the compliant probands. Conclusions: This newly developed form of music-based audio therapy is associated with reduced depressive symptoms and high treatment compliance and offers new treatment options for patients with the need for additional therapy or requiring an alternative approach. http://dx.doi.org/10.1016/j.eujim.2015.09.013 Exploring the experience and impact of therapeutic touch treatments to nurse colleagues Amanda Bulette Coakley Massachusetts General Hospital, USA E-mail address: [email protected]. Introduction: Therapeutic touch (TT) reduces anxiety, stress and improves comfort and wellbeing. Providers and recipients of TT benefit from treatments. Nurses provide care which is
3
physically and emotionally demanding. The research question was ‘what is the experience and impact of providing and receiving therapeutic touch treatments on nurses?’ The hypothesis was that participants, who receive and offer TT interventions, will have significantly lower cortisol levels, decreased blood pressure and reduced anxiety levels, and significantly improved comfort and well-being. The specific aims were: (1) To test the efficacy of a TT influencing stress, sense of comfort and well-being by: (a) Comparison of physiologic stress markers of cortisol, blood pressure levels and state anxiety levels (STAI) of nurses offering and receiving TT. (b) Comparison of comfort and wellbeing as measured with visual analog scales. (2) To qualitatively understand the experiences of nurses providing and receiving therapeutic touch (TT). Methods: Nurses provided TT treatments to colleagues. Before and after each treatment vital signs; visual analog scales for comfort and wellbeing; state anxiety survey (STAI); and oral cortisol levels were collected. Staff attended focus groups analysis: quantitative data was analyzed through a series of paired t-tests. Results: VAS for comfort, well being and STAI total was statistically significantly improved for TT providers and receivers. Focus group data was analyzed using content analysis. Three themes were identified: (1) TT promoted healing, comfort, and relaxation for nurses. (2) Challenges related to centering, scheduling time, and a busy environment. (3) Nurses identified the benefits of TT for their patients and colleagues. http://dx.doi.org/10.1016/j.eujim.2015.09.014 Randomized controlled trial of yoga and meditation for menopausal symptoms in breast cancer survivors Holger Cramer ∗ , Sybille Rabilber, Romy Lauche, Sherko Kümmel, Gustav Dobos University of Duisburg-Essen, Faculty of Medicine, Department of Internal and Integrative Medicine, Kliniken Essen-Mitte, Klinik für Naturheilkunde und Integrative Medizin, Kliniken Essen-Mitte, Knappschafts-Krankenhaus, Am Deimelsberg 34a, Essen 45276, Germany E-mail address: [email protected]. Introduction: Treatment options for menopausal symptoms in breast cancer survivors remain very limited. The purpose of this trial was to evaluate the effects of a 12-week traditional hatha yoga and meditation intervention on menopausal symptoms in breast cancer survivors. Methods: Patients were randomly assigned to a 12-weeks yoga and meditation intervention or usual care. Primary outcome measure was total menopausal symptoms (Menopause Rating Scale [MRS] total score). Secondary outcome measures included MRS subscales, cancer-specific quality of life (Functional Assessment of Cancer Therapy – Breast), fatigue (Functional Assessment of Chronic Illness Therapy – Fatigue),