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Erythrocyte band 3 protein
Comp. Biochem. Physiol. Vol. 99A, No. 1/2, pp. 259--262, 1991 Pergamon Press pie. Printed in Great Britain
BOOK REVIEWS
Protein Methylation---Edited by W. K. PAIK and S. KIM. 451 pp. 1990. CRC Press, Boca Raton, FL. $195.
Animal Physiology; Adaptation and Environment. 4th Editinn---By K, SeHMn3T-Nmt~'EN. 602pp. 1990. Cambridge University Press, Cambridge. $39.50.
Many proteins are methylated. Lysine, arginine, histidine, proline, aianine, giutamine and asparagine residues of certain proteins are post synthetically N-methylated. Glutamic and aspartic residues are O.methylesterified; cysteine and methionine residues are S-methylated. Protein methylation is important in bacterial chemotaxis, carnitine biosynthesis, DNA repair, membrane protein repair and growth. Methylation is also important in calmodulin, cytochrome c, nuclear acids, histones, ribosomal proteins and heat shock proteins. All these are discussed in depth in the present interesting volume which will tell you all you want to know about protein methylation.
This new edition has been brought up to date, 200 new references have been added, changes have been made in the diagrams, each chapter has a brief synopsis indicating what is to follow. It is a very readable and interesting account and presents essential information in a clear and informative manner. Still the best text on animal physiology. The Physiology of Psychological Disorders; Schizophrenia, Depression, Anxiety and Substance Abuse--By J. CJ. HOLLANDSWORTH. 318pp. 1990. Plenum Press, New York. $37.50.
Fc Receptors and the Action of Antibodies--Edited by H. METZGER. 368 pp. 1990. American Society for Microbiology, Washington, DC. $65.
The study of the clinical physiological psychology of man assumes that the clinical disorders will have a physiological/biochemical basis upon which genetic and social factors can interact. The topics dealt with are; diagnosis, DSM-III and IIIR; temperaments; genes and environment; schizophrenia ["schizophrenia however does not lend itself to bring thought of a single construct. Reliability coefficients for its diagnosis are generally low, with a range for 0.27 to 0.77 with an average of 0.56"]; mood disorders; anxiety; substance abuse; implications for clinical practice. There are also 16 summary sections that discuss topics such as heritability of schizophrenia; neurotransmitters; respiration and acid base balance; psychoactive substances. The book makes the physiological psychology relevant to those with clinical interests, and also gives clinical background to neuroscientists.
Although antibodies can bind directly to antigens, in many cases antibodies react with other proteins and this then stimulates different effector systems. The proteins bind to the invariant Fc region of the antibody and are called Fc receptors. It is through these receptors that antibodies regulate their own biosynthesis, transport, catabolism; initiate complement cascade; stimulate phagocytosis; trigger release of cellular mediators and promote cell mediated killing of other cells and microorganisms. This book deals with these topics under sections on structure and function of antibodies; receptor mediated transport and metabolism; activation of complement system; antibody mediated endocytosis; Fc mediated secretion; Fc mediated killing; antibody mediated regulation of lymphocytes. A fascinating story.
Laboratory Methodology in Biuehemlstry. Amino Acid Analysis and Protein Sequencing--Edited by C. FxNI, A. FLORIDI, V. N. FI~rELLI and B. W.-LmnOLD. 263 pp. 1990. CRC Press, Boca Raton, FL. $129.95. After a short history of protein sequence analysis, the chapters deal with mass spectrometry-GLC; DABS-C1; DABITC; HPLC: use of computers in protein sequencing; mapping of ligand binding sites; ASP-N endoproteinase; peptide isolation in subnanomole range; hormone purification; electro-blotting; fast atom bombardment mass spectrometry. Sufficient experimental details are provided to help with the procedures, and references are given to allow the reader to follow up specific points. Erythroeyte Band 3 Protein---By J. M. SALHANY.213pp. 1990. CRC Press, Boca Raton, FL. $124.95.
Purines in Cellular Signalling; Targets for New Drugs---Edited by K. A. JACOBSON,J. W. DALY and V. MANGANIELLO. 467 pp. 1990. Springer, Berlin. DM 95. This is the proceedings of a symposium held in Maryland, September 1989. Adenosine, ATP, cAMP, cGMP act at different receptor sites to produce a wide range of effects. Adenosine and ATP act on surface receptors; cAMP and cGMP are intracellular messengers. The 54 papers in this volume discuss the properties of the different receptors, the development of selective synthetic agonists and antagonists, the nature and role of phosphodiesterases and their inhibitors. The role of purines in cardiac arrhythmias, cardiac contractility, kidney function, CNS, visual transuction, platelet aggregation, lipolysis, is discussed, together with the possibilities of the development of new and selective drugs acting on purinergic systems.
The band 3 protein (band 3) is responsible for anion transport across the RBC membrane. This single author volume provides an excellent survey of the biochemistry and kinetics of anion transport. The chapters deal with history and perspective; disposition and structure of band 3; mechanisms of band 3 ion exchange; cytosolic associations of band 3 and heterotropic allosteric control of anion exchange; band 3 porter [organic acid transport, water and urea transport, glucose transport]. A very interesting account of an important subject.
Epithelial Secretion of Water and Electrolytes--Edited by J. A. YOUNOand P. WoNo. 279 pp. 1990. Springer, Berlin. DM 238. The studies of Silva et al. on salt and water secretion by the salt secreting gland of the dogfish provided a boost to the understanding of transepithelial fluid secretion. This book brings this new information together. The topics covered are; general aspects of secretion [epithelial CI channels; 259
BOOK REVIEWS
Protein Methylation---Edited by W. K. PAIK and S. KIM. 451 pp. 1990. CRC Press, Boca Raton, FL. $195.
Animal Physiology; Adaptation and Environment. 4th Editinn---By K, SeHMn3T-Nmt~'EN. 602pp. 1990. Cambridge University Press, Cambridge. $39.50.
Many proteins are methylated. Lysine, arginine, histidine, proline, aianine, giutamine and asparagine residues of certain proteins are post synthetically N-methylated. Glutamic and aspartic residues are O.methylesterified; cysteine and methionine residues are S-methylated. Protein methylation is important in bacterial chemotaxis, carnitine biosynthesis, DNA repair, membrane protein repair and growth. Methylation is also important in calmodulin, cytochrome c, nuclear acids, histones, ribosomal proteins and heat shock proteins. All these are discussed in depth in the present interesting volume which will tell you all you want to know about protein methylation.
This new edition has been brought up to date, 200 new references have been added, changes have been made in the diagrams, each chapter has a brief synopsis indicating what is to follow. It is a very readable and interesting account and presents essential information in a clear and informative manner. Still the best text on animal physiology. The Physiology of Psychological Disorders; Schizophrenia, Depression, Anxiety and Substance Abuse--By J. CJ. HOLLANDSWORTH. 318pp. 1990. Plenum Press, New York. $37.50.
Fc Receptors and the Action of Antibodies--Edited by H. METZGER. 368 pp. 1990. American Society for Microbiology, Washington, DC. $65.
The study of the clinical physiological psychology of man assumes that the clinical disorders will have a physiological/biochemical basis upon which genetic and social factors can interact. The topics dealt with are; diagnosis, DSM-III and IIIR; temperaments; genes and environment; schizophrenia ["schizophrenia however does not lend itself to bring thought of a single construct. Reliability coefficients for its diagnosis are generally low, with a range for 0.27 to 0.77 with an average of 0.56"]; mood disorders; anxiety; substance abuse; implications for clinical practice. There are also 16 summary sections that discuss topics such as heritability of schizophrenia; neurotransmitters; respiration and acid base balance; psychoactive substances. The book makes the physiological psychology relevant to those with clinical interests, and also gives clinical background to neuroscientists.
Although antibodies can bind directly to antigens, in many cases antibodies react with other proteins and this then stimulates different effector systems. The proteins bind to the invariant Fc region of the antibody and are called Fc receptors. It is through these receptors that antibodies regulate their own biosynthesis, transport, catabolism; initiate complement cascade; stimulate phagocytosis; trigger release of cellular mediators and promote cell mediated killing of other cells and microorganisms. This book deals with these topics under sections on structure and function of antibodies; receptor mediated transport and metabolism; activation of complement system; antibody mediated endocytosis; Fc mediated secretion; Fc mediated killing; antibody mediated regulation of lymphocytes. A fascinating story.
Laboratory Methodology in Biuehemlstry. Amino Acid Analysis and Protein Sequencing--Edited by C. FxNI, A. FLORIDI, V. N. FI~rELLI and B. W.-LmnOLD. 263 pp. 1990. CRC Press, Boca Raton, FL. $129.95. After a short history of protein sequence analysis, the chapters deal with mass spectrometry-GLC; DABS-C1; DABITC; HPLC: use of computers in protein sequencing; mapping of ligand binding sites; ASP-N endoproteinase; peptide isolation in subnanomole range; hormone purification; electro-blotting; fast atom bombardment mass spectrometry. Sufficient experimental details are provided to help with the procedures, and references are given to allow the reader to follow up specific points. Erythroeyte Band 3 Protein---By J. M. SALHANY.213pp. 1990. CRC Press, Boca Raton, FL. $124.95.
Purines in Cellular Signalling; Targets for New Drugs---Edited by K. A. JACOBSON,J. W. DALY and V. MANGANIELLO. 467 pp. 1990. Springer, Berlin. DM 95. This is the proceedings of a symposium held in Maryland, September 1989. Adenosine, ATP, cAMP, cGMP act at different receptor sites to produce a wide range of effects. Adenosine and ATP act on surface receptors; cAMP and cGMP are intracellular messengers. The 54 papers in this volume discuss the properties of the different receptors, the development of selective synthetic agonists and antagonists, the nature and role of phosphodiesterases and their inhibitors. The role of purines in cardiac arrhythmias, cardiac contractility, kidney function, CNS, visual transuction, platelet aggregation, lipolysis, is discussed, together with the possibilities of the development of new and selective drugs acting on purinergic systems.
The band 3 protein (band 3) is responsible for anion transport across the RBC membrane. This single author volume provides an excellent survey of the biochemistry and kinetics of anion transport. The chapters deal with history and perspective; disposition and structure of band 3; mechanisms of band 3 ion exchange; cytosolic associations of band 3 and heterotropic allosteric control of anion exchange; band 3 porter [organic acid transport, water and urea transport, glucose transport]. A very interesting account of an important subject.
Epithelial Secretion of Water and Electrolytes--Edited by J. A. YOUNOand P. WoNo. 279 pp. 1990. Springer, Berlin. DM 238. The studies of Silva et al. on salt and water secretion by the salt secreting gland of the dogfish provided a boost to the understanding of transepithelial fluid secretion. This book brings this new information together. The topics covered are; general aspects of secretion [epithelial CI channels; 259