- Email: [email protected]
Evaluation of lens surface appearance and ocular physiology with three silicone hydrogel daily disposables
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Abstracts / Contact Lens & Anterior Eye 35S (2012) e1–e32
15 Evaluation of lens surface appearance and ocular physiology with three silicone hydrogel daily disposables Nancy J. Keir ∗ , Jalaiah Varikooty, Doris Richter, Lyndon Jones, Craig Woods, Desmond Fonn Centre for Contact Lens Research, Waterloo, Canada E-mail address: [email protected] (N.J. Keir)
∗
Purpose: To evaluate lens surface and ocular physiology after 8 h of wear with 3 silicone hydrogel daily disposables (SHDDs). Method: 104 participants wore 3 SHDDs, DAILIES TOTAL1 (DT1), Clariti 1-Day (C1D) and 1-Day Acuvue TruEye (AVTE) each for 3 days. On Day 1, biomicroscopy including corneal staining (0–10,000) and conjunctival staining (0–100), pre-lens non-invasive tear break-up time (NITBUT), graded lens wettability and deposition (0–4) were assessed in the morning and on Day 3 after 8 h of wear. Investigators were masked to lens type; however identifiers may have been visible during lens assessment at the slit lamp. Repeated measures ANOVA with Tukey HSD post hoc testing and McNemar’s test were used (p < 0.05). Results: Mean corneal staining was clinically acceptable, but lower with DT1 (25 ± 54) and C1D (38 ± 70) compared to AVTE (74 ± 117) (both p < 0.01). Conjunctival staining was greater with C1D (30 ± 12) compared to AVTE (10 ± 8) and DT1 (4 ± 5) (p < 0.01). Fewer eyes exhibited conjunctival indentation with DT1 (n = 1) compared to C1D (n = 70, p < 0.01) and AVTE (n = 11, p = 0.02). Mean NITBUT after 8 h was 5.7 s with DT1; 1 s longer than C1D and AVTE (both p < 0.01). Graded wettability was better for DT1 than C1D and AVTE (mean differences of 0.27 and 0.34, respectively, both p < 0.01) and graded deposition was 0.31 and 0.13 lower with DT1 compared to AVTE (p < 0.01) and C1D (p = 0.01), respectively. Conclusions: In-eye lens performance was acceptable for all 3 SHDDs, however DT1 exhibited the least impact on ocular physiology and the least change in lens surface appearance after 8 h of wear. http://dx.doi.org/10.1016/j.clae.2012.08.018 16 The impact of cosmetics on the physicaldimension and optical performance of silicone hydrogel contact lenses Doerte Luensmann ∗ , Sruthi Srinivasan, Mili Yu, Jeffery Yang, Lyndon Jones Centre for Contact Lens Research, University of Waterloo, Waterloo, Canada ∗ E-mail address: [email protected] (D. Luensmann) Purpose: To evaluate the impact of cosmetics on silicone hydrogel (SiHy) contact lens shape, lens power and optical performance. Method: In this in vitro experiment, seven SiHy materials were coated with one of nine common cosmetics, including hand creams (3), eye makeup removers (3) and mascaras (3). Diameter, sagittal depth and base curve were determined using the Optimec Chiltern, while lens power and optical performance were assessed using the Rotlex Contest Plus (n = 6 for each lens type). Measurements were repeated after a single Clear Care® cleaning cycle. Results: Makeup removers had the greatest impact on diameter, sagittal depth and base curve, resulting in changes of up to 0.5mm, 0.15mm and 0.77 mm, respectively. The hand creams and mascaras had little impact on these parameters, however significant differences were observed between lens types. Optical performance was significantly reduced with all mascaras and resulted in a decrease of approximately 3 units on a 0–10 scale (10 = uniform power distri-
bution) for five lens types exposed to waterproof mascara (p < 0.01). Most hand creams and makeup removers had minimal impact on image quality. Lens power did not change significantly with any of the cosmetics (±0.25 D, p > 0.05). Clear Care® cleaning resulted in minor recovery of the different lens parameters and efficiency varied between cosmetics. Conclusions: Some eye makeup removers and waterproof mascaras can significantly change the contact lens shape and optical performance, to a degree that it may impact in vivo lens performance. The recovery after cleaning is low, suggesting these changes are long-lasting. http://dx.doi.org/10.1016/j.clae.2012.08.019 17 Quantitative colour analysis for iris colour classification Magda L. Michna ∗ , John R. Buch Johnson & Johnson Vision Care Inc., Jacksonville, USA E-mail address: [email protected] (M.L. Michna)
∗
Purpose: Accurate iris colour representation is important for consistency in subjective iris colour classification, as well as monitoring changes of iris colour with reference to ocular conditions. Methods of classifying iris colour available in scientific literature are often based on subjective classification, or describe quantitative methodology, but do not provide a visual reference scale. The purpose of this work was to use quantitative colour analysis to develop a method for iris colour classification and create a visual scale. Method: Digital iris images were captured using high optical quality photographic equipment and image exposure and lighting intensities optimised to ensure accuracy and consistency. Colour calibration of digital images was performed using a colour gamut checker. The digital images were analysed to determine their colour coordinates based on the CIE L*a*b colour space. The colour (‘a’ and ‘b’) and lightness (‘L’) was determined for each image. Results: The CIE L*a*b colour space, based on models of human colour perception, provides the best classification scheme for images that are to be used in subjective colour assessment. Each image was classified into five colour groups (grey, blue, green, hazel, or brown) based on the CIE L*a*b coordinates. The images were then classified on their lightness (light, medium, or dark) and a 15-point iris colour scale was created. Conclusions: We present a novel methodology for classifying iris colour using sophisticated image capturing methods and colour analysis. Classification of iris images using this method ensures accuracy in colour representation, making it ideal as a reference tool for subjective evaluation. http://dx.doi.org/10.1016/j.clae.2012.08.020 18 Clinical visual performance of different front surface eccentricity in PROSE Rajeswari Mahadevan ∗ , Amudha Oli Arumugam, Madhumathi, Nandhini Ganesan, Jaya Sowjanya Siddireddy Medical Research Foundation, Chennai, India E-mail address: [email protected] (R. Mahadevan)
∗
Purpose: To report the clinical visual performance of different front surface eccentricity (FSE) in patients with corneal ectasia. Method: Records of 17 subjects fitted with the PROSE (Prosthetic Replacement of the Ocular Surface Ecosystem), a fluid-ventilated gas-permeable scleral lens, for corneal ectasia (ker-
Abstracts / Contact Lens & Anterior Eye 35S (2012) e1–e32
15 Evaluation of lens surface appearance and ocular physiology with three silicone hydrogel daily disposables Nancy J. Keir ∗ , Jalaiah Varikooty, Doris Richter, Lyndon Jones, Craig Woods, Desmond Fonn Centre for Contact Lens Research, Waterloo, Canada E-mail address: [email protected] (N.J. Keir)
∗
Purpose: To evaluate lens surface and ocular physiology after 8 h of wear with 3 silicone hydrogel daily disposables (SHDDs). Method: 104 participants wore 3 SHDDs, DAILIES TOTAL1 (DT1), Clariti 1-Day (C1D) and 1-Day Acuvue TruEye (AVTE) each for 3 days. On Day 1, biomicroscopy including corneal staining (0–10,000) and conjunctival staining (0–100), pre-lens non-invasive tear break-up time (NITBUT), graded lens wettability and deposition (0–4) were assessed in the morning and on Day 3 after 8 h of wear. Investigators were masked to lens type; however identifiers may have been visible during lens assessment at the slit lamp. Repeated measures ANOVA with Tukey HSD post hoc testing and McNemar’s test were used (p < 0.05). Results: Mean corneal staining was clinically acceptable, but lower with DT1 (25 ± 54) and C1D (38 ± 70) compared to AVTE (74 ± 117) (both p < 0.01). Conjunctival staining was greater with C1D (30 ± 12) compared to AVTE (10 ± 8) and DT1 (4 ± 5) (p < 0.01). Fewer eyes exhibited conjunctival indentation with DT1 (n = 1) compared to C1D (n = 70, p < 0.01) and AVTE (n = 11, p = 0.02). Mean NITBUT after 8 h was 5.7 s with DT1; 1 s longer than C1D and AVTE (both p < 0.01). Graded wettability was better for DT1 than C1D and AVTE (mean differences of 0.27 and 0.34, respectively, both p < 0.01) and graded deposition was 0.31 and 0.13 lower with DT1 compared to AVTE (p < 0.01) and C1D (p = 0.01), respectively. Conclusions: In-eye lens performance was acceptable for all 3 SHDDs, however DT1 exhibited the least impact on ocular physiology and the least change in lens surface appearance after 8 h of wear. http://dx.doi.org/10.1016/j.clae.2012.08.018 16 The impact of cosmetics on the physicaldimension and optical performance of silicone hydrogel contact lenses Doerte Luensmann ∗ , Sruthi Srinivasan, Mili Yu, Jeffery Yang, Lyndon Jones Centre for Contact Lens Research, University of Waterloo, Waterloo, Canada ∗ E-mail address: [email protected] (D. Luensmann) Purpose: To evaluate the impact of cosmetics on silicone hydrogel (SiHy) contact lens shape, lens power and optical performance. Method: In this in vitro experiment, seven SiHy materials were coated with one of nine common cosmetics, including hand creams (3), eye makeup removers (3) and mascaras (3). Diameter, sagittal depth and base curve were determined using the Optimec Chiltern, while lens power and optical performance were assessed using the Rotlex Contest Plus (n = 6 for each lens type). Measurements were repeated after a single Clear Care® cleaning cycle. Results: Makeup removers had the greatest impact on diameter, sagittal depth and base curve, resulting in changes of up to 0.5mm, 0.15mm and 0.77 mm, respectively. The hand creams and mascaras had little impact on these parameters, however significant differences were observed between lens types. Optical performance was significantly reduced with all mascaras and resulted in a decrease of approximately 3 units on a 0–10 scale (10 = uniform power distri-
bution) for five lens types exposed to waterproof mascara (p < 0.01). Most hand creams and makeup removers had minimal impact on image quality. Lens power did not change significantly with any of the cosmetics (±0.25 D, p > 0.05). Clear Care® cleaning resulted in minor recovery of the different lens parameters and efficiency varied between cosmetics. Conclusions: Some eye makeup removers and waterproof mascaras can significantly change the contact lens shape and optical performance, to a degree that it may impact in vivo lens performance. The recovery after cleaning is low, suggesting these changes are long-lasting. http://dx.doi.org/10.1016/j.clae.2012.08.019 17 Quantitative colour analysis for iris colour classification Magda L. Michna ∗ , John R. Buch Johnson & Johnson Vision Care Inc., Jacksonville, USA E-mail address: [email protected] (M.L. Michna)
∗
Purpose: Accurate iris colour representation is important for consistency in subjective iris colour classification, as well as monitoring changes of iris colour with reference to ocular conditions. Methods of classifying iris colour available in scientific literature are often based on subjective classification, or describe quantitative methodology, but do not provide a visual reference scale. The purpose of this work was to use quantitative colour analysis to develop a method for iris colour classification and create a visual scale. Method: Digital iris images were captured using high optical quality photographic equipment and image exposure and lighting intensities optimised to ensure accuracy and consistency. Colour calibration of digital images was performed using a colour gamut checker. The digital images were analysed to determine their colour coordinates based on the CIE L*a*b colour space. The colour (‘a’ and ‘b’) and lightness (‘L’) was determined for each image. Results: The CIE L*a*b colour space, based on models of human colour perception, provides the best classification scheme for images that are to be used in subjective colour assessment. Each image was classified into five colour groups (grey, blue, green, hazel, or brown) based on the CIE L*a*b coordinates. The images were then classified on their lightness (light, medium, or dark) and a 15-point iris colour scale was created. Conclusions: We present a novel methodology for classifying iris colour using sophisticated image capturing methods and colour analysis. Classification of iris images using this method ensures accuracy in colour representation, making it ideal as a reference tool for subjective evaluation. http://dx.doi.org/10.1016/j.clae.2012.08.020 18 Clinical visual performance of different front surface eccentricity in PROSE Rajeswari Mahadevan ∗ , Amudha Oli Arumugam, Madhumathi, Nandhini Ganesan, Jaya Sowjanya Siddireddy Medical Research Foundation, Chennai, India E-mail address: [email protected] (R. Mahadevan)
∗
Purpose: To report the clinical visual performance of different front surface eccentricity (FSE) in patients with corneal ectasia. Method: Records of 17 subjects fitted with the PROSE (Prosthetic Replacement of the Ocular Surface Ecosystem), a fluid-ventilated gas-permeable scleral lens, for corneal ectasia (ker-