- Email: [email protected]
Exercise training in very old adults with mild cognitive impairment: Improvements on BDNF peripheral levels and cognition
P722
Poster Presentations: P3
(A), 19.7610.7 ng/mL (S)] which were not significantly different from each other (p¼0.33). Increases in serum and CSF levels of BDNF were not significantly correlated. Serum BDNF levels did not significantly correlate with age, MMSE, or VO2max. Conclusion: These preliminary results, on this ongoing study, suggest an equal effect on BDNF levels with stretch or aerobic exercise in older adults. Other behavioral factors including diet and sleep patterns, which have also been shown to affect BDNF levels, are likely to be attributing factors.
P3-235
EXERCISE TRAINING IN VERY OLD ADULTS WITH MILD COGNITIVE IMPAIRMENT: IMPROVEMENTS ON BDNF PERIPHERAL LEVELS AND COGNITION
Kyung-Phil Kwak, Dongguk University Gyeongju Hospital, Gyeongju, South Korea. Contact e-mail: [email protected] Background: We investigated to evaluate efficacy of exercise on cognition in very older adults with MCI andto analyze the effects of a exercise program on peripheral BDNF levels. Methods: The participants were 102 patients with MCI assigned randomly to exercise program therapy group and a control group. 121 participant (75w91 years old) were randomized to a sequence of 48 session of exercise training. The main goal was to analyze the effects of a 24-week program on peripheral BDNF levels in very elderly with MCI. Cognitive functions were assessed by MMSE, GDS, BNT, block design, semantic fluency and matrix reasoning prior to and after the intervention. Results: The study results showed a significant improvement of BDNF (p<.05) peripheral concentrations. Cognitive functions also presented significant (p<.05) improvements for trained group; MMSE(1.83), GDS(0.71), BNT(3.11), block design(12.46), semantic fluency(1.23) and matrix reasoning(3.21). Conclusions: Exercise training is an effective method for impovement of BDNF level and cognition in very older MCI.
P3-236
HEALTHY ELDERLY’S CARE OF PEOPLE WITH DEMENTIA IS ASSOCIATED WITH IMPROVEMENTS OF WORD LIST MEMORY OF PEOPLE WITH DEMENTIA AND CAREGIVER’S QUALITY OF LIFE
Seong-Jin Cho1, Seung-Gul Kang1, Byeong Kil Yeon1, Sungman Chang2, Gachon University Gil Hospital, Incheon, South Korea; 2Kyungpook National University Hospital, Daegu, South Korea. Contact e-mail: sjcho@ gilhospital.com
1
Background: Caring the people with dementia by the healthy elderly who is not a family member is one of the new paradigms of the dementia care program in South Korea. This study aimed to investigate whether the dementia care program by the healthy elderly would improve the cognitive function of people with dementia and quality of life of the healthy elderly caregiver. Methods: All of the dementia patients were diagnosed by the medical doctors. We excluded the severe dementia patients who had received the service of the nursing home or the care helper by the government. The healthy elderly were educated about the care programs such as a kind of cognitive rehabilitations, talk companion, aid in the medication administration, emotional support, and hygiene care. We evaluated the cognitive
function of the dementia patients at baseline and after 6 months of the service using the Korean version of the Consortium to Establish a Registry for Alzheimer’s disease (CERAD-K). We also evaluated the quality of life of the healthy elderly caregiver using WHOQOL-BREF at baseline and after 6 months. Results: A total of 132 dementia patients and 199 elderly caregiver participated in this study. The word list memory of CERAD-K of the dementia patients improved after 6 months (p¼0.006). However, the total score of the CERAD-K after 6 months did not differ from the total score at baseline. The WHOQOL-BREF score among the elderly caregiver improved significantly (p¼0.015). Conclusions: These data suggest that dementia care including the simple cognitive rehabilitation by elderly caregiver is associated with the improved cognitive function of the dementia patients and quality of life of the healthy elderly caregiver. To verify these results, a larger-scale study is needed in the future.
P3-237
IDENTIFYING AND MANAGING HIGH-RISK DOMAINS OF CARE: GUN SAFETY, DRIVING, ALCOHOL ABUSE, AND SUICIDAL IDEATION IN VETERANS WITH DEMENTIA
Amy J. Mitchell, Michelle M. Hilgeman, T. Scott Martin, A. Lynn Snow, Catherine D. Ball, Veterans Affairs, Tuscaloosa, AL, USA. Contact e-mail: [email protected] Project Description: Aspects of the military experience may place Veterans at increased risk of harm in the context of dementia; this is particularly true in rural areas where access to services is limited. We will describe a novel dementia-focused care consultation telephone service within a Veterans Affairs medical center for rural-dwelling Veterans with dementia and their caregivers. Through the regular use of a comprehensive needs assessment tool, we have identified four particularly high risk domains of care that present with regularity: Gun Safety, Driving, Alcohol Abuse, and Suicidal Ideation. We will describe the psychosocial interventions we use that help identify, manage, and monitor these cases to minimize risks for the Veterans, their caregivers, and the public. We will also present evaluation data indicating that these intervention strategies typically produce overall reduced stress and improved quality of life for the Veterans and their caregivers. The case consultation program utilizes a clinical database that achieves both clinical documentation and data tracking aims. Aggregating these data allowed us to identify the highest risk domains of care in our population, and allows us to review the types of interventions provided and the effectiveness of those interventions. In addition, satisfaction surveys and consumer interviews have provided insight into the effectiveness of the approaches used in this case consultation service. These data, as well as case examples, will be presented. 213 Veterans with dementia and their caregivers received services over a two year period. Many of these families voiced concern in at least one of the high risk domains, with many expressing concern across more than one. Individualized action plans are specifically tailored to each family based on their identified trigger while promoting their dignity and self-determination. Telephone-delivered care can be used to successfully manage high risk behaviors remotely for individuals with dementia. More clinical programs like this one are needed to support
Poster Presentations: P3
(A), 19.7610.7 ng/mL (S)] which were not significantly different from each other (p¼0.33). Increases in serum and CSF levels of BDNF were not significantly correlated. Serum BDNF levels did not significantly correlate with age, MMSE, or VO2max. Conclusion: These preliminary results, on this ongoing study, suggest an equal effect on BDNF levels with stretch or aerobic exercise in older adults. Other behavioral factors including diet and sleep patterns, which have also been shown to affect BDNF levels, are likely to be attributing factors.
P3-235
EXERCISE TRAINING IN VERY OLD ADULTS WITH MILD COGNITIVE IMPAIRMENT: IMPROVEMENTS ON BDNF PERIPHERAL LEVELS AND COGNITION
Kyung-Phil Kwak, Dongguk University Gyeongju Hospital, Gyeongju, South Korea. Contact e-mail: [email protected] Background: We investigated to evaluate efficacy of exercise on cognition in very older adults with MCI andto analyze the effects of a exercise program on peripheral BDNF levels. Methods: The participants were 102 patients with MCI assigned randomly to exercise program therapy group and a control group. 121 participant (75w91 years old) were randomized to a sequence of 48 session of exercise training. The main goal was to analyze the effects of a 24-week program on peripheral BDNF levels in very elderly with MCI. Cognitive functions were assessed by MMSE, GDS, BNT, block design, semantic fluency and matrix reasoning prior to and after the intervention. Results: The study results showed a significant improvement of BDNF (p<.05) peripheral concentrations. Cognitive functions also presented significant (p<.05) improvements for trained group; MMSE(1.83), GDS(0.71), BNT(3.11), block design(12.46), semantic fluency(1.23) and matrix reasoning(3.21). Conclusions: Exercise training is an effective method for impovement of BDNF level and cognition in very older MCI.
P3-236
HEALTHY ELDERLY’S CARE OF PEOPLE WITH DEMENTIA IS ASSOCIATED WITH IMPROVEMENTS OF WORD LIST MEMORY OF PEOPLE WITH DEMENTIA AND CAREGIVER’S QUALITY OF LIFE
Seong-Jin Cho1, Seung-Gul Kang1, Byeong Kil Yeon1, Sungman Chang2, Gachon University Gil Hospital, Incheon, South Korea; 2Kyungpook National University Hospital, Daegu, South Korea. Contact e-mail: sjcho@ gilhospital.com
1
Background: Caring the people with dementia by the healthy elderly who is not a family member is one of the new paradigms of the dementia care program in South Korea. This study aimed to investigate whether the dementia care program by the healthy elderly would improve the cognitive function of people with dementia and quality of life of the healthy elderly caregiver. Methods: All of the dementia patients were diagnosed by the medical doctors. We excluded the severe dementia patients who had received the service of the nursing home or the care helper by the government. The healthy elderly were educated about the care programs such as a kind of cognitive rehabilitations, talk companion, aid in the medication administration, emotional support, and hygiene care. We evaluated the cognitive
function of the dementia patients at baseline and after 6 months of the service using the Korean version of the Consortium to Establish a Registry for Alzheimer’s disease (CERAD-K). We also evaluated the quality of life of the healthy elderly caregiver using WHOQOL-BREF at baseline and after 6 months. Results: A total of 132 dementia patients and 199 elderly caregiver participated in this study. The word list memory of CERAD-K of the dementia patients improved after 6 months (p¼0.006). However, the total score of the CERAD-K after 6 months did not differ from the total score at baseline. The WHOQOL-BREF score among the elderly caregiver improved significantly (p¼0.015). Conclusions: These data suggest that dementia care including the simple cognitive rehabilitation by elderly caregiver is associated with the improved cognitive function of the dementia patients and quality of life of the healthy elderly caregiver. To verify these results, a larger-scale study is needed in the future.
P3-237
IDENTIFYING AND MANAGING HIGH-RISK DOMAINS OF CARE: GUN SAFETY, DRIVING, ALCOHOL ABUSE, AND SUICIDAL IDEATION IN VETERANS WITH DEMENTIA
Amy J. Mitchell, Michelle M. Hilgeman, T. Scott Martin, A. Lynn Snow, Catherine D. Ball, Veterans Affairs, Tuscaloosa, AL, USA. Contact e-mail: [email protected] Project Description: Aspects of the military experience may place Veterans at increased risk of harm in the context of dementia; this is particularly true in rural areas where access to services is limited. We will describe a novel dementia-focused care consultation telephone service within a Veterans Affairs medical center for rural-dwelling Veterans with dementia and their caregivers. Through the regular use of a comprehensive needs assessment tool, we have identified four particularly high risk domains of care that present with regularity: Gun Safety, Driving, Alcohol Abuse, and Suicidal Ideation. We will describe the psychosocial interventions we use that help identify, manage, and monitor these cases to minimize risks for the Veterans, their caregivers, and the public. We will also present evaluation data indicating that these intervention strategies typically produce overall reduced stress and improved quality of life for the Veterans and their caregivers. The case consultation program utilizes a clinical database that achieves both clinical documentation and data tracking aims. Aggregating these data allowed us to identify the highest risk domains of care in our population, and allows us to review the types of interventions provided and the effectiveness of those interventions. In addition, satisfaction surveys and consumer interviews have provided insight into the effectiveness of the approaches used in this case consultation service. These data, as well as case examples, will be presented. 213 Veterans with dementia and their caregivers received services over a two year period. Many of these families voiced concern in at least one of the high risk domains, with many expressing concern across more than one. Individualized action plans are specifically tailored to each family based on their identified trigger while promoting their dignity and self-determination. Telephone-delivered care can be used to successfully manage high risk behaviors remotely for individuals with dementia. More clinical programs like this one are needed to support