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Experimental studies of the effect of low frequency ultrasound on the wettability of the surface of titanium dental implants
269 implant placement were performed. The resorption of sinus bone graft, marginal bone loss around the implants, and complications were assessed. Findings: The average resorption of bone graft materials to evaluate possible case after one year was 2.99 ± 1.06 mm (19 cases), after two years was 5.28 ± 2.43 mm (8 cases) and after three years was 6.39 ± 2.88 mm (8 cases). The total average observation period of the patients was 27.5 ± 17.67 months and the final average absorption was 4.76 ± 2.96 mm. The number of postoperative complications was 8 of 18 patients. Screw loosening, periimplantitis, pain, prosthesis dislodgement, haematoma, sinusitis, and bleeding were observed. Implant survival rate was 100% until the final follow-up period. The final alveolar bone resorption was 1.67 ± 1.36 mm around the implant. Conclusion: The reparation of large maxillary sinus perforation using collagen membrane is effective and successful treatment. http://dx.doi.org/10.1016/j.ijom.2017.02.906 Affinity of octacalcium phosphate collagen composite for titanium dental implants T. Kawai ∗ , K. Matsui, Y. Ezoe, F. Kajii, O. Suzuki, T. Takahashi, S. Kamakura Division of Oral and Maxillofacial Surgery, Tohoku University Graduate School of Dentistry, Sendai, Japan Background and Objective: Octacalcium phosphate (OCP) and its collagen composite (OCP/collagen) are good bone substitute materials. We previously showed that OCP/collagen can be used to repair human jaw bone defects without any associated abnormalities. The present study investigated whether OCP/collagen could be applied to dental implant treatment using a dog tooth extraction socket model. Methods: OCP/collagen was prepared as previously described. The second and third premolars were extracted from bilateral mandibles of dogs; each extraction socket was extended, and titanium dental implants were placed in each socket. OCP/collagen was inserted in the space around a titanium dental implant. Autologous bone and beta-tricalcium phosphate (-TCP) were used to fill two of the other sockets, while the untreated socket (i.e. no bone substitute material) served as a control. Three months after the operation, we examined the osseointegration of each bone substitute material with the surface of the titanium dental implant. Results: Radiographic and histological evaluation revealed bone formation around implants in sockets containing OCP/collagen, autologous bone or -TCP. In histomorphometric analyses, the periimplant bone areas (BA) percentage and bone-implant contact (BIC) percentage were measured. There was no difference in BA percentage between OCP/collagen, autologous bone, and -TCP; however, BIC percentage differed significantly between the three materials, although not between OCP/collagen and autologous bone. Conclusion: These results demonstrate that OCP/collagen is a good alternative to autologous bone as a bone substitute material in dental implant treatment. http://dx.doi.org/10.1016/j.ijom.2017.02.907
Elimination of deformities of alveolar processes and dentition with the use of mini implants A. Khomich ∗ , I. Khomich, S. Khomich Belarussian State Medical University, Belarus Background: In many clinical cases it is difficult, and sometimes impossible, to eliminate deformations of dentition and alveolar processes only by means of orthodontic or surgical treatment. Therefore, in order to implement an effective movement of the teeth and surrounding tissues, it is often necessary to use miniscrews for better, and often the only possible, support. Objectives: To analyse methods of eliminating deformations of the alveolar processes and dentition in patients using miniscrews. Methods: Treatment of patients with deformities of alveolar processes of upper and lower jaws included orthodontic treatment with brackets and additional anchorage on miniscrews, sometimes the movement was carried out only by miniscrews and elastics. In some cases the procedure was supplemented by compactosteotomy. Tapered miniscrews were used and loaded immediately after installation. In cases with implant loosening, they were reinstalled at a new location. Findings: Duration of treatment depended on the severity of deformation. The best effect was achieved when installing implants on both sides of the alveolar process. Use of miniscrews provides faster and more effective result in eliminating deformations. Conclusion: Elimination of deformations of dentition and alveolar processes with the use of orthodontic miniimplants goes on faster and without unwanted movement of adjacent teeth. http://dx.doi.org/10.1016/j.ijom.2017.02.908 Experimental studies of the effect of low frequency ultrasound on the wettability of the surface of titanium dental implants I. Khomich ∗ , S. Rubnikovich, S. Khomich, A. Khomich Belarusian State Medical Academy of Postgraduate Education, Minsk, Belarus Background: It is known that wettability of dental implant surface is one of the key factors influencing quality of osseointegration. Objectives: To study the effect of low-intensity pulsed ultrasound on the wettability of the surface of titanium dental implants in experimental medical-technical model. Methods: The medical-technical model included ultrasonic generator, fixtures for implant samples, camcorder and Petri dish with sterile 0.9% physiological solution, and allowed simultaneous immersion of apical part of test and control implants into wetting solution. Empirically the base resonant frequency for given size of implants was found. Ultrasonication of implants with found frequency allowed “forced wetting” of implant surface. Findings: Results of experiment showed that application of ultrasound with resonant frequency to dental implants caused “forced wetting” of the surface of all the test samples (32 dental implants with SLA surface) within 5–7 s. Surface wetting of control samples (32 dental implant with SLA surface) was not observed. We assume, that effect of “forced wetting” of dental implant surface is possible due to increase of surface energy caused by ultrasound application, which destroys surface tension of wetting agent.
270 Conclusion: Based on the performed experimental studies it can be concluded, that ultrasonic application to dental implants could increase their surface wettability, especially in porous and complex surfaces with micro- and nanotopography. http://dx.doi.org/10.1016/j.ijom.2017.02.909 Histomorphometric results of low-intensity pulsed ultrasound application in dental implantation I. Khomich ∗ , S. Rubnikovich, S. Khomich, A. Khomich Belarusian State Medical Academy of Postgraduate Education, Minsk, Belarus Background: Studies show that osteoreparation processes proceed more intensively at sites with low-intensity pulsed ultrasound (LIPUS) application to 47.2–66.8% (P < 0.001) compared to the ones without. Objectives: To evaluate histomorphometric changes around dental implants after ultrasound application in the early healing stages. Methods: Histomorphometric evaluation of periimplant bone tissue with and without LIPUS was performed. Findings: In animal models without LIPUS at all stages of the experiment trabecular bone area with high density of osteogenic cells was significantly lower (Mann-Whitney U Test, P < 0.05) than in group with LIPUS application to implants and periimplant tissues. The area of newly formed bone around the implant bed was significantly higher (up to 25.6–36.5% (P < 0.001)) in animal models with LIPUS exposure comparing to the ones without. The combined effect of LIPUS on implants and periimplant tissues has expressed a linear relationship (R = 0.96)–and resulted in marked increase of the area of active osteoblastic surface (P = 0.0332). Newly formed coarse fibre and lamellar bone tissue formation was observed around implant bed in LIPUS group. In the control group there was a delay of bone maturation and the predominance of coarse-fibered bone tissue at a later terms of osteosynthesis compared to LIPUS group. Conclusion: We assume that the combined effect of LIPUS on dental implants and periimplant tissues improves osteoreparation and osseointegration processes. http://dx.doi.org/10.1016/j.ijom.2017.02.910 Results of morphological studies on the effectiveness of dental implantation using low-intensity pulsed ultrasound I. Khomich ∗ , S. Rubnikovich, S. Khomich, A. Khomich Belarusian State Medical Academy of Postgraduate Education, Minsk, Belarus Background: Ultrasound application to bone fractures in early stages has shown acceleration of callus formation and ossification in several studies. Objectives: To study the morphological changes around installed dental implants after ultrasound application in the early healing stages. Methods: In all experimental groups osseointegration processes took place without breaking the sequence of reparation stages. However, the timing and extent of the repair and osseointegration in the control and experimental groups differed depending on the therapeutic effects of the methods.
Findings: Delay of bone maturation, presence of necrotic zones, immature granulation tissue in the early stages, and the predominance of coarse-fibered bone tissue at a later stage of osteosynthesis were found in the first group. In the second group application of low-intensity pulsed ultrasound (LIPUS) to dental implants and periimplant tissues of the operated area contributed to the formation of bone tissue similar in histostructure to the parent bone. The area of the newly formed periimplant bone tissue in the group with LIPUS was significantly higher than that in the first group at all stages of the experiment. Conclusion: The use of LIPUS during dental implantation induces osteoreparation processes by stimulating angiogenesis in the granulation and the newly formed bone. http://dx.doi.org/10.1016/j.ijom.2017.02.911 Clinical outcome of implants and sinus bone grafts in the case of maxillary sinusitis: retrospective clinical study H.S. Kim ∗ , J.K. Ku, Y.K. Kim Department of Oral and Maxillofacial Surgery, Seoul National University Bundang Hospital, Seongnam, Korea Objectives: To evaluate clinical outcome of implants and sinus bone grafts in maxillary sinusitis patients. Methods: This study included 29 patients (59 implants) who contracted maxillary sinusitis before or after sinus bone graft or implantation. Treatment cases were categorised into three groups according to the time of sinusitis treatment, bone graft and implantation; Group I (n = 18): maxillary sinusitis treated before bone graft and implantation, Group II (n = 22): maxillary sinusitis treated after bone graft, but before implantation, and Group III (n = 19): maxillary sinusitis treated after bone graft and implantation. Among the groups, mean marginal bone loss (MBL), survival rate, sinus membrane perforation at bone graft, relationship with smoke, primary and secondary stabilities of implant were evaluated. Findings: During average observation period of 70.58 months, Group II showed significantly more MBL than Group I and III (P < 0.05). The implant survival rates of Group I (94.44 ± 0.24%) and Group III (89.47 ± 0.32%) were significantly higher than that of Group II (63.16 ± 0.50%; P < 0.001). Group II showed dominant frequency in sinus membrane perforation at bone graft surgery. Group II also showed significantly lower primary stability (P < 0.001), but no statistical difference in secondary stability when compared with the other groups. More smokers were in Group III (P < 0.001), but no relations with MBL, survival rate and primary/secondary stabilities were found. Conclusion: MBL and frequency of sinus membrane perforation were highest in the Group II, and its survival rate was significantly lower than the other groups. Early diagnosis and treatment of maxillary sinusitis before or after the graft and implantation showed better clinical outcome of dental implants. http://dx.doi.org/10.1016/j.ijom.2017.02.912
Elimination of deformities of alveolar processes and dentition with the use of mini implants A. Khomich ∗ , I. Khomich, S. Khomich Belarussian State Medical University, Belarus Background: In many clinical cases it is difficult, and sometimes impossible, to eliminate deformations of dentition and alveolar processes only by means of orthodontic or surgical treatment. Therefore, in order to implement an effective movement of the teeth and surrounding tissues, it is often necessary to use miniscrews for better, and often the only possible, support. Objectives: To analyse methods of eliminating deformations of the alveolar processes and dentition in patients using miniscrews. Methods: Treatment of patients with deformities of alveolar processes of upper and lower jaws included orthodontic treatment with brackets and additional anchorage on miniscrews, sometimes the movement was carried out only by miniscrews and elastics. In some cases the procedure was supplemented by compactosteotomy. Tapered miniscrews were used and loaded immediately after installation. In cases with implant loosening, they were reinstalled at a new location. Findings: Duration of treatment depended on the severity of deformation. The best effect was achieved when installing implants on both sides of the alveolar process. Use of miniscrews provides faster and more effective result in eliminating deformations. Conclusion: Elimination of deformations of dentition and alveolar processes with the use of orthodontic miniimplants goes on faster and without unwanted movement of adjacent teeth. http://dx.doi.org/10.1016/j.ijom.2017.02.908 Experimental studies of the effect of low frequency ultrasound on the wettability of the surface of titanium dental implants I. Khomich ∗ , S. Rubnikovich, S. Khomich, A. Khomich Belarusian State Medical Academy of Postgraduate Education, Minsk, Belarus Background: It is known that wettability of dental implant surface is one of the key factors influencing quality of osseointegration. Objectives: To study the effect of low-intensity pulsed ultrasound on the wettability of the surface of titanium dental implants in experimental medical-technical model. Methods: The medical-technical model included ultrasonic generator, fixtures for implant samples, camcorder and Petri dish with sterile 0.9% physiological solution, and allowed simultaneous immersion of apical part of test and control implants into wetting solution. Empirically the base resonant frequency for given size of implants was found. Ultrasonication of implants with found frequency allowed “forced wetting” of implant surface. Findings: Results of experiment showed that application of ultrasound with resonant frequency to dental implants caused “forced wetting” of the surface of all the test samples (32 dental implants with SLA surface) within 5–7 s. Surface wetting of control samples (32 dental implant with SLA surface) was not observed. We assume, that effect of “forced wetting” of dental implant surface is possible due to increase of surface energy caused by ultrasound application, which destroys surface tension of wetting agent.
270 Conclusion: Based on the performed experimental studies it can be concluded, that ultrasonic application to dental implants could increase their surface wettability, especially in porous and complex surfaces with micro- and nanotopography. http://dx.doi.org/10.1016/j.ijom.2017.02.909 Histomorphometric results of low-intensity pulsed ultrasound application in dental implantation I. Khomich ∗ , S. Rubnikovich, S. Khomich, A. Khomich Belarusian State Medical Academy of Postgraduate Education, Minsk, Belarus Background: Studies show that osteoreparation processes proceed more intensively at sites with low-intensity pulsed ultrasound (LIPUS) application to 47.2–66.8% (P < 0.001) compared to the ones without. Objectives: To evaluate histomorphometric changes around dental implants after ultrasound application in the early healing stages. Methods: Histomorphometric evaluation of periimplant bone tissue with and without LIPUS was performed. Findings: In animal models without LIPUS at all stages of the experiment trabecular bone area with high density of osteogenic cells was significantly lower (Mann-Whitney U Test, P < 0.05) than in group with LIPUS application to implants and periimplant tissues. The area of newly formed bone around the implant bed was significantly higher (up to 25.6–36.5% (P < 0.001)) in animal models with LIPUS exposure comparing to the ones without. The combined effect of LIPUS on implants and periimplant tissues has expressed a linear relationship (R = 0.96)–and resulted in marked increase of the area of active osteoblastic surface (P = 0.0332). Newly formed coarse fibre and lamellar bone tissue formation was observed around implant bed in LIPUS group. In the control group there was a delay of bone maturation and the predominance of coarse-fibered bone tissue at a later terms of osteosynthesis compared to LIPUS group. Conclusion: We assume that the combined effect of LIPUS on dental implants and periimplant tissues improves osteoreparation and osseointegration processes. http://dx.doi.org/10.1016/j.ijom.2017.02.910 Results of morphological studies on the effectiveness of dental implantation using low-intensity pulsed ultrasound I. Khomich ∗ , S. Rubnikovich, S. Khomich, A. Khomich Belarusian State Medical Academy of Postgraduate Education, Minsk, Belarus Background: Ultrasound application to bone fractures in early stages has shown acceleration of callus formation and ossification in several studies. Objectives: To study the morphological changes around installed dental implants after ultrasound application in the early healing stages. Methods: In all experimental groups osseointegration processes took place without breaking the sequence of reparation stages. However, the timing and extent of the repair and osseointegration in the control and experimental groups differed depending on the therapeutic effects of the methods.
Findings: Delay of bone maturation, presence of necrotic zones, immature granulation tissue in the early stages, and the predominance of coarse-fibered bone tissue at a later stage of osteosynthesis were found in the first group. In the second group application of low-intensity pulsed ultrasound (LIPUS) to dental implants and periimplant tissues of the operated area contributed to the formation of bone tissue similar in histostructure to the parent bone. The area of the newly formed periimplant bone tissue in the group with LIPUS was significantly higher than that in the first group at all stages of the experiment. Conclusion: The use of LIPUS during dental implantation induces osteoreparation processes by stimulating angiogenesis in the granulation and the newly formed bone. http://dx.doi.org/10.1016/j.ijom.2017.02.911 Clinical outcome of implants and sinus bone grafts in the case of maxillary sinusitis: retrospective clinical study H.S. Kim ∗ , J.K. Ku, Y.K. Kim Department of Oral and Maxillofacial Surgery, Seoul National University Bundang Hospital, Seongnam, Korea Objectives: To evaluate clinical outcome of implants and sinus bone grafts in maxillary sinusitis patients. Methods: This study included 29 patients (59 implants) who contracted maxillary sinusitis before or after sinus bone graft or implantation. Treatment cases were categorised into three groups according to the time of sinusitis treatment, bone graft and implantation; Group I (n = 18): maxillary sinusitis treated before bone graft and implantation, Group II (n = 22): maxillary sinusitis treated after bone graft, but before implantation, and Group III (n = 19): maxillary sinusitis treated after bone graft and implantation. Among the groups, mean marginal bone loss (MBL), survival rate, sinus membrane perforation at bone graft, relationship with smoke, primary and secondary stabilities of implant were evaluated. Findings: During average observation period of 70.58 months, Group II showed significantly more MBL than Group I and III (P < 0.05). The implant survival rates of Group I (94.44 ± 0.24%) and Group III (89.47 ± 0.32%) were significantly higher than that of Group II (63.16 ± 0.50%; P < 0.001). Group II showed dominant frequency in sinus membrane perforation at bone graft surgery. Group II also showed significantly lower primary stability (P < 0.001), but no statistical difference in secondary stability when compared with the other groups. More smokers were in Group III (P < 0.001), but no relations with MBL, survival rate and primary/secondary stabilities were found. Conclusion: MBL and frequency of sinus membrane perforation were highest in the Group II, and its survival rate was significantly lower than the other groups. Early diagnosis and treatment of maxillary sinusitis before or after the graft and implantation showed better clinical outcome of dental implants. http://dx.doi.org/10.1016/j.ijom.2017.02.912