Factors associated with the outcomes in activity in daily living in children with autism spectrum disorder

Research Posters Research Poster 687 Factors associated with the outcomes in activity in daily living in children with autism spectrum disorder Chia-Ling Chen (Department of Physical Medicine & Rehabilitation, Chang Gung Memorial Hospital), Chung-yao Chen, Hsieh-ching Chen, Chih-jou Lai, Chia-ying Chong, Wen-chung Tsai Research Objectives: To identify the factors associated with the outcome in the activity in daily living (ADL) in children with autism spectrum disorder (ASD). Design: A Cross-sectional study. Setting: An outpatient clinic of a tertiary teaching hospital. Participants: Forty-three children with ASD (3-12 years) were enrolled in this study. Four factors were identified and assessed: age; sex; Box Block Test (BBT), and Peabody Picture Vocabulary Test (PPVT). Interventions: Not applicable. Main Outcome Measure(s): ADL outcome was assessed by pediatric functional independence measure (WeeFIM), which consists of Self-care, Mobility, and Cognition domains. Results: Regression analyses showed age and PPVT score predicted the outcomes in the Mobility and Cognition domains, and Total WeeFIM (adjusted r2Z0.18 - 0.48, p<0.05). The BBT score predicted the outcomes in the Self-care domain (adjusted r2Z0.42, p<0.01). Conclusions: Findings suggest that good motor and vocabulary abilities in children with ASD may benefit most from therapy on ADL. Key Words: Autism spectrum disorder, activity in daily living, predictor, motor function, speech Disclosures: None disclosed. Research Poster 689 Fall Risk and Mobility Assessment in Comparison between Early and Late Rehabilitation in Stroke- a Cohort Study in Bangladesh Moshiur Rahman Khasru (Bangabandhu Sheikh Mujib Medical University), Abul Khair Mohammad Salek Research Objectives: Introduction/Background. Introduction: Stroke is a leading cause of disability in Bangladesh (BD). Many investigators have argued that early rehabilitation could maximize recovery from stroke. Aim is to examine comparison of fall risk between patient having early and delayed initiation of rehabilitative interventions after stroke. Design: Data was collected prospectively for 12 months in 2013 in this multi-centre study in Bangladesh after obtaining IRB approval and consent from patients. Setting: Stroke patient from Seven tertiary level hospital across the country were included in the study. Participants: Four groups of patients depending on commencement of Rehabilitation: a) Very Early: 0-24 hrs post stroke b) Early: 24-72 hrs post stroke. c) Intermediate: 3-7 days post stroke d) Late: 8-60 days post stroke. All respondent was evaluated during enrollment, after 3rd & 12 weeks after initiation rehabilitation interventions. Interventions: Demography, Co-morbidity, NIH score. Main Outcome Measure(s): NIH Stroke Scale, Berg Balance Scale, Spasticity. Results: Among all respondent (nZ235) 57.4% were >60 years of age, 51.1% were male, all were right handed, Ischemic stroke were 70.2%. Comorbidity assessment results showed DM38.3%, Hypertension 95.7%, IHD 4.3%. Among all respondent 17.0%, 42.6%, 23.4% and 17.0% were belonged in very early, early, intermediate and late rehab group respectively. Stroke severity was mild 21.3%, Moderate 59.6% and severe 19.1% on NIHSS score. During enrollment (n-235) High mobility restriction 85.1%, Moderate mobility restriction 8.5% and Low mobility restriction 6.4% on Rivermead Mobility Index and High Fall Risk, Moderate Risk Fall and Low Fall Risk on Berg Balance Scale respectively. Duration between stroke and Rehabilitation initiation cross tabulation with Rivermead Mobility Index

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e109 and Berg Balance Scale, improvement on mobility and reduction of fall risk is found in all groups respectively but more improvement in very early group and “p” value was <0.001 in both scale in both 3rd week and 12th week follow-up. On multinomial logistic regression analysis, factors shows the independent affiliation with highly mobility restriction to moderate mobility restriction of Rivermead Mobility Index included younger age <60years, male patient, married, hemorrhagic stroke, stroke on bilateral site. Factors shows the independent affiliation with highly fall risk to moderate fall risk of Berg Balance Scale included younger age <60years, male patient, married, hemorrhagic stroke, stroke on bilateral site. Conclusions: Limited evidence exists in this cohort. Key Words: Fall Risk, Spasticity, Stroke, Rehabilitation Disclosures: None disclosed. Research Poster 691 Longitudinal Change and Associated Factors of Post-stroke Depression: A Prospective Follow-up Study EunJoo Kim (Pusan Yangsan National University), Ae Ra Kim (Pusan Yangsan National University Hospital) Research Objectives: To investigate the prevalence of depression and to identify factors associated with post-stroke depression. Design: This study design is prospective longitudinal follow-up. Setting: Institutional practice. Participants: A total of 229 patients of stroke participated in this study. Interventions: The prevalence assessments were performed at acute or subacute stage (T0), 6 months after onset of stroke (T1), 12 months after onset of stroke (T2) and 24 months after onset of stroke (T3). Main Outcome Measure(s): To identify factors associated with post-stroke depression, we evaluated cognitive function, motor function, ambulatory function and activity of daily living. Results: The prevalence of post-stroke depression were 37%, 19%, 16% and 8% at T0, T1, T2 and T3, respectively. Post-stroke depression were more frequent in over 65 years old. Post-stroke depression was associated with cognitive function at all T0 to T3, activity of daily living at T0 to T2 and ambulatory function at T3. The prevalence of post-stroke depression was decreased gradually after onset of stroke. Cognitive function affected post-stroke depression from acute to 24 months after onset of stroke. Conclusions: This study showed the assessment and understanding of the post-stroke depression is an important part of rehabilitation after stroke. Key Words: Stroke, post-stroke depression, factor analysis, prospective longitudinal Disclosures: None disclosed. Research Poster 692 Peak Cardiorespiratory Responses During Aquatic and Land Treadmill in Patients with Subacute Stroke So Young Lee (Jeju National University Hospital), Yong Ki Lee Research Objectives: To investigate cardiorespiratory responses elicited during exercise stress tests using an aquatic treadmill (ATM) and a land treadmill (TM) in patients with subacute stroke. Design: Cross-sectional research. Setting: Rehabilitation center. Participants: Twenty-one subacute stroke patients (13 males and 8 females; average age, 57.0 years). Interventions: all subjects participated in two symptom-limited incremental exercise protocols (aquatic treadmill and a land treadmill). Main Outcome Measure(s): Oxygen consumption (Vo2), metabolic equivalents (METs), heart rate (HR), and respiratory exchange ratio (RER) were measured continuously with peak values. Results: When comparing peak cardiorespiratory responses during ATM and TM protocols, Vo2 peak (22.0 vs 20.0, pZ0.02), METs peak (6.3 vs 5.8, pZ0.02) were significantly greater in ATM than TM, and RPE peak