Cancer Letters 342 (2014) 167
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Featuring the special issue editor Prof. Panayiotidis received his Ph.D. in Toxicology (2004) from the University of Colorado Health Sciences Center, Department of Pharmaceutical Sciences, School of Pharmacy, Colorado, USA. From 2004 to 2006, he joined the Laboratory of Signal Transduction at the National Institute of Environmental Health Sciences (NIH/NIEHS), Research Triangle Park, North Carolina, USA where his work led to new observations on how deregulation of ionic imbalance modulates the progression of apoptosis induced by activation of death receptors. From 2006 to 2007, he was appointed a Research Assistant Professor at the University of North Carolina-Chapel Hill, Department of Nutrition, School of Public Health, North Carolina, USA followed by an Assistant Professor position (2007–2009) at the University of Nevada-Reno, School of Community Health Sciences, Nevada, USA. Upon his return to Europe, he has held a number of academic positions including a Visiting Professor position (2009–2010) at the University of Thessaly, Biology Unit, Volos, Greece and an Assistant Professor of Molecular Pathology position (2012–2013) at the University of Ioannina, Laboratory of Pathological Anatomy, Medical School, Ioannina, Greece while he maintained an Adjunct Assistant Professor position (2009–2011) with the University of Nevada-Reno, School of Community Health Sciences, Nevada, USA. Currently, he is a Professor of Nutrition & Toxicology at the School of Life Sciences, Heriot Watt University, Edinburgh, Scotland, UK. His research is focused in cancer prevention and the development of molecular biomarkers for cancer therapeutic outcome. For this purpose, he is utilizing genomic technologies that are pathway-focused and involve the profiling of genes known to be involved in the multistage process of carcinogenesis. In particular, he is investigating the molecular mechanisms by which apoptosis becomes deregulated during progression to malignancy and how the epigenetic pathways regulate apoptotic gene expression during malignant transformation. Moreover, he is investigating into the role of natural product compounds and how they influence the epigenetic pathways in preventing against cancer development. Ultimately, his research
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aims to discover the identity of those epigenetic events underlying defective apoptosis and, perhaps, their significance as potential biomarkers in (i) clinical cancer research and (ii) nutritional intervention studies. Prof. Panayiotidis is an Associate Editor for the Journals of Biochemical Technology, Pharmacology & Therapeutics and an Editorial Board Member for Mutation Research-Genetic Toxicology & Environmental Mutagenesis, Cancer Letters, International Journal of Experimental Pathology and Toxicology Mechanisms & Methods. In addition, Prof. Panayiotidis is an Active Member of the Education Quality Accreditation Commission, an Active Member of the European Association for Cancer Research (EACR) and a Scientific Advisory Board Member for the International Institute of Anticancer Research (IIAR). Moreover, Prof. Panayiotidis has a number of peer-reviewed publications in international journals, pertaining to his area of expertise, whereas he maintains collaborations with a number of research groups at various Institutions across the world. Finally, Prof. Panayiotidis has been a principal investigator in a number of research grants including, amongst others, a Marie Curie International Reintegration Grant, a University of Nevada Junior Faculty Award, a Colorado Tobacco Research Program Grant award, a Nutricia Research Foundation International Training Fellowship and a Marilyn Gentry Fellowship administered by the American Institute for Cancer Research & World Cancer Research Fund. Conflict of interest None of the authors has any financial and personal relationships with other people or organisations that could inappropriately influence (bias) their work. Mihalis I. Panayiotidis School of Life Sciences, Heriot Watt University, James Watt Building, Riccarton, Edinburgh EH14 4AS, Scotland, UK Tel.: +44 (0)131 4514313. E-mail address:
[email protected]