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FIBROLIPOMA OF THE ORAL CAVITY - CASE REPORT
ABSTRACTS
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of the tongue." Intraoral examination revealed a sessile nodule of asymptomatic white color with firm consistency and palpation of regular shape and surface, measuring approximately 7 mm, with an evolution time of approximately 2 years and located in the tongue. An excisional biopsy was performed. The histopathologic examination revealed the definitive diagnosis of giant cell fibroma. The patient is under follow-up with no recurrence.
FIBROLIPOMA OF THE ORAL CAVITY CASE REPORT. EMERSON LUCAS DA SILVA COIMBRA, JOSE DE ASSIS SILVA JUNIOR, ^ A, ANA FLAVIA WILLIAM NAPOLITANO CORRE e SCHUELER DE ASSUMP¸C AO LEITE, SIMONE DE ^ QUEIROZ CHAVES LOURENCO ¸ and, MONICA LAGE DA ROCHA Fibrolipoma is a benign tumor characterized by the presence of mature adipose cells separated by areas of dense fibroconnective tissue. This tumor can affect any part of the body, but it is rare in the oral cavity. The objective of this study is to present a case of fibrolipoma in a 67-year-old white woman with a complaint of "lesion in buccal mucosa." The patient has drug-controlled hypertension. At the intraoral examination, an asymptomatic pediculated nodule of pink color with firm consistency and smooth surface measuring approximately 19 mm and located in the buccal mucosa was identified. An excisional biopsy was performed. The histopathologic examination revealed the definitive diagnosis of fibrolipoma. The patient is under follow-up with no recurrence.
INTRAOSSEOUS BENIGN FIBROUS HISTIOCYTOMA RICH IN GRANULAR CELLS OF THE MAXILLA: IMMUNOHISTOCHEMICAL ANALYSIS. ROSE MARA ORTEGA, MATHEUS HENRIQUE LOPES DOMINGUETE, KAMILA PRADO PEREIRA GRACIANO DOMINGUETE, CATIA MARISA GAZOLLA DE OLIVEIRA, LUCIANA YAMAMOTO ALMEIDA, LUCAS RIBEIRO TEIXEIRA and, JORGE ESQUICHE LEON Benign fibrous histiocytoma (BFH) is a mesenchymal tumor usually constituted of spindle and epithelioid cells, which occurs predominantly in the bone and soft tissues. Histopathologically, it reveals 2 types of cells, fibroblasts and histiocytes, arranged in storiform pattern and interlacing fascicles without nuclear pleomorphism, necrosis, and low mitotic activity. The granular cell variant of BFH is extremely rare. A 64-year-old woman was referred presenting an osteolytic lesion in the anterior region of the maxilla, mimicking nasopalatine duct cyst. After excisional biopsy, microscopy revealed a storiform arrangement of spindle to epithelioid cells, most of them with PAS-D positive granular cytoplasm, surrounded by sclerotic fibrous stroma. Immunohistochemistry showed positivity for vimentin, CD68, CD163, a smooth muscle actin, and focal FXIIIA. Ki-67 was <3%. The patient presented well after 1-year of follow-up. To our knowledge, this is the first report of BFH rich in granular cells in intraosseous location affecting the maxilla.
LASER THERAPY FOR TREATMENT OF ORAL MUCOSITIS: CASE REPORT. ELISA KAUARK e BISPO, HAYANA FONTES, MAYARA SIMOES RAMOS LIMA, JULIANA BORGES DE LIMA DANTAS,
OOOO January 2020 MANOELA CARRERA MARTINEZ PEREIRA, ALENA RIBEIRO ALVES PEIXOTO MEDRADO and, GABRIELA MARTINS BOTELHO A 60-year-old male patient with a history of chronic drinking and smoking was diagnosed as having squamous cell carcinoma on the tongue beyond surgical therapeutic possibility. Radiotherapy and chemotherapy were indicated. After the fifth cycle of chemotherapy concomitant with radiotherapy, the patient reported pain in the oral cavity, which worsened after the use of methotrexate to treat peripheral neuropathy. The condition progressed to extensive oral ulcers requiring the use of a nasogastric tube for feeding. Low-intensity laser (AsGaAl, 680 nm, 2 J/cm2) was applied on the ulcers in a punctual and continuous manner. After 4 sessions, there was a significant improvement of the condition, with catheter removal and the patient being released from the hospital. The laser therapy proved to be effective in the treatment of oral mucositis lesions, reducing the pain and severity of the lesions, being a noninvasive and safe form of treatment.
GRANULAR CELL TUMOR OF LOWER LIP: CASE REPORT. LUIZA DE MOURA CARVALHO FIGUEIRA, LILIAN MACHADO DE SOUSA ALMEIDA, RAFAELA ELVIRA ROZZA-DEMENEZES, ADRIANNA MILAGRES, DANIELLE CASTEX CONDE, ELIANA PEDRA DIAS and, KARIN SOARES GONCALVES ¸ CUNHA Granular cell tumor is a rare benign soft-tissue neoplasm with a predilection for the mouth. Its most common location is in the tongue followed by buccal mucosa. There is a predilection for the female sex, and it occurs most often between the fourth and sixth decade. It is usually normochromic, but occasionally it may present a yellow coloration. Our aim is to report a case of a 21-year-old black male patient presenting a firm yellowish sessile nodule, measuring 1 cm in the lower lip with an evolution of 3 years. The clinical diagnoses were fibrolipoma and traumatic fibroma. An excisional biopsy was performed, and in the histopathologic examination a proliferation of large and polygonal cells with abundant eosinophilic and granular cytoplasm and vesicular nuclei were observed, leading to the diagnosis of granular cell tumor. The patient has been followed up for 5 months, and no recurrence was observed.
LASER THERAPY AS ADJUNCTIVE TREATMENT FOR ORAL MUCOSITIS IN A PEDIATRIC PATIENT WITH NON-HODGKIN LYMPHOMA. LARISSA GABRIELY OLIVEIRA CAVALCANTI, JULIANELLY ALVES BISERRA, JULIANA ^ LO CAVALCANTE DE OLIVEIRA, MORGANA RABE RODRIGUES LAFAYETTE DE OLIVEIRA, MARIA ^ GABRIELA CAVALCANTI DE ARAUJO, MONICA MOREIRA DIAS CRUZ and, JOSE ANCHIETA DE BRITO Lymphomas represent the third most common type of cancer in young people, classified into non-Hodgkin (NHL) or Hodgkin lymphoma. NHL arises when B or T cells, which are involved in the protection, become malignant, growing uncontrollably, "contaminating" the lymphatic system. Characterized by a high degree of malignancy with pathology and immunology of different characteristics. Radiotherapy or chemotherapy are treatments performed for this disease, which may lead to oral manifestations because of its cytotoxicity. A 13-year-old male patient diagnosed
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of the tongue." Intraoral examination revealed a sessile nodule of asymptomatic white color with firm consistency and palpation of regular shape and surface, measuring approximately 7 mm, with an evolution time of approximately 2 years and located in the tongue. An excisional biopsy was performed. The histopathologic examination revealed the definitive diagnosis of giant cell fibroma. The patient is under follow-up with no recurrence.
FIBROLIPOMA OF THE ORAL CAVITY CASE REPORT. EMERSON LUCAS DA SILVA COIMBRA, JOSE DE ASSIS SILVA JUNIOR, ^ A, ANA FLAVIA WILLIAM NAPOLITANO CORRE e SCHUELER DE ASSUMP¸C AO LEITE, SIMONE DE ^ QUEIROZ CHAVES LOURENCO ¸ and, MONICA LAGE DA ROCHA Fibrolipoma is a benign tumor characterized by the presence of mature adipose cells separated by areas of dense fibroconnective tissue. This tumor can affect any part of the body, but it is rare in the oral cavity. The objective of this study is to present a case of fibrolipoma in a 67-year-old white woman with a complaint of "lesion in buccal mucosa." The patient has drug-controlled hypertension. At the intraoral examination, an asymptomatic pediculated nodule of pink color with firm consistency and smooth surface measuring approximately 19 mm and located in the buccal mucosa was identified. An excisional biopsy was performed. The histopathologic examination revealed the definitive diagnosis of fibrolipoma. The patient is under follow-up with no recurrence.
INTRAOSSEOUS BENIGN FIBROUS HISTIOCYTOMA RICH IN GRANULAR CELLS OF THE MAXILLA: IMMUNOHISTOCHEMICAL ANALYSIS. ROSE MARA ORTEGA, MATHEUS HENRIQUE LOPES DOMINGUETE, KAMILA PRADO PEREIRA GRACIANO DOMINGUETE, CATIA MARISA GAZOLLA DE OLIVEIRA, LUCIANA YAMAMOTO ALMEIDA, LUCAS RIBEIRO TEIXEIRA and, JORGE ESQUICHE LEON Benign fibrous histiocytoma (BFH) is a mesenchymal tumor usually constituted of spindle and epithelioid cells, which occurs predominantly in the bone and soft tissues. Histopathologically, it reveals 2 types of cells, fibroblasts and histiocytes, arranged in storiform pattern and interlacing fascicles without nuclear pleomorphism, necrosis, and low mitotic activity. The granular cell variant of BFH is extremely rare. A 64-year-old woman was referred presenting an osteolytic lesion in the anterior region of the maxilla, mimicking nasopalatine duct cyst. After excisional biopsy, microscopy revealed a storiform arrangement of spindle to epithelioid cells, most of them with PAS-D positive granular cytoplasm, surrounded by sclerotic fibrous stroma. Immunohistochemistry showed positivity for vimentin, CD68, CD163, a smooth muscle actin, and focal FXIIIA. Ki-67 was <3%. The patient presented well after 1-year of follow-up. To our knowledge, this is the first report of BFH rich in granular cells in intraosseous location affecting the maxilla.
LASER THERAPY FOR TREATMENT OF ORAL MUCOSITIS: CASE REPORT. ELISA KAUARK e BISPO, HAYANA FONTES, MAYARA SIMOES RAMOS LIMA, JULIANA BORGES DE LIMA DANTAS,
OOOO January 2020 MANOELA CARRERA MARTINEZ PEREIRA, ALENA RIBEIRO ALVES PEIXOTO MEDRADO and, GABRIELA MARTINS BOTELHO A 60-year-old male patient with a history of chronic drinking and smoking was diagnosed as having squamous cell carcinoma on the tongue beyond surgical therapeutic possibility. Radiotherapy and chemotherapy were indicated. After the fifth cycle of chemotherapy concomitant with radiotherapy, the patient reported pain in the oral cavity, which worsened after the use of methotrexate to treat peripheral neuropathy. The condition progressed to extensive oral ulcers requiring the use of a nasogastric tube for feeding. Low-intensity laser (AsGaAl, 680 nm, 2 J/cm2) was applied on the ulcers in a punctual and continuous manner. After 4 sessions, there was a significant improvement of the condition, with catheter removal and the patient being released from the hospital. The laser therapy proved to be effective in the treatment of oral mucositis lesions, reducing the pain and severity of the lesions, being a noninvasive and safe form of treatment.
GRANULAR CELL TUMOR OF LOWER LIP: CASE REPORT. LUIZA DE MOURA CARVALHO FIGUEIRA, LILIAN MACHADO DE SOUSA ALMEIDA, RAFAELA ELVIRA ROZZA-DEMENEZES, ADRIANNA MILAGRES, DANIELLE CASTEX CONDE, ELIANA PEDRA DIAS and, KARIN SOARES GONCALVES ¸ CUNHA Granular cell tumor is a rare benign soft-tissue neoplasm with a predilection for the mouth. Its most common location is in the tongue followed by buccal mucosa. There is a predilection for the female sex, and it occurs most often between the fourth and sixth decade. It is usually normochromic, but occasionally it may present a yellow coloration. Our aim is to report a case of a 21-year-old black male patient presenting a firm yellowish sessile nodule, measuring 1 cm in the lower lip with an evolution of 3 years. The clinical diagnoses were fibrolipoma and traumatic fibroma. An excisional biopsy was performed, and in the histopathologic examination a proliferation of large and polygonal cells with abundant eosinophilic and granular cytoplasm and vesicular nuclei were observed, leading to the diagnosis of granular cell tumor. The patient has been followed up for 5 months, and no recurrence was observed.
LASER THERAPY AS ADJUNCTIVE TREATMENT FOR ORAL MUCOSITIS IN A PEDIATRIC PATIENT WITH NON-HODGKIN LYMPHOMA. LARISSA GABRIELY OLIVEIRA CAVALCANTI, JULIANELLY ALVES BISERRA, JULIANA ^ LO CAVALCANTE DE OLIVEIRA, MORGANA RABE RODRIGUES LAFAYETTE DE OLIVEIRA, MARIA ^ GABRIELA CAVALCANTI DE ARAUJO, MONICA MOREIRA DIAS CRUZ and, JOSE ANCHIETA DE BRITO Lymphomas represent the third most common type of cancer in young people, classified into non-Hodgkin (NHL) or Hodgkin lymphoma. NHL arises when B or T cells, which are involved in the protection, become malignant, growing uncontrollably, "contaminating" the lymphatic system. Characterized by a high degree of malignancy with pathology and immunology of different characteristics. Radiotherapy or chemotherapy are treatments performed for this disease, which may lead to oral manifestations because of its cytotoxicity. A 13-year-old male patient diagnosed