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First results of prostate cancer screening programme in Belarus
B54: First results of prostate cancer screening programme in Belarus Sukonko O.1, Krasny S.2, Tarend D.3 1
National Center of Oncology and Medical Radiology, Director, Minsk, Belarus, 2National Center of Oncology and Medical Radiology, Vice-Director, Minsk, Belarus, 3Minsk Regional Hospital, Dept. of Urology 1, Minsk, Belarus INTRODUCTION & OBJECTIVES: Prostate cancer screening is one of the most discussed questions in modern oncourology. There are supporters and opponents of screening programmes who represents their arguments based on different studies. The problem of prostate cancer in Belarus became very acute. This pathology has gained all features of socially significant disease. At first, because during last 10 years we see the 27,9% growth of morbidity among men that exceeds such parameter for lung and skin cancers. At second, due to late diagnosis more then 50% of new cases of prostate cancer are revealed on 3-4 stages, when radical treatment can not be applied. The main objective of our study is to analyze the effectiveness of screening programme at example of 3 regions: towns - Soligorsk and Molodechno and Pervomayskiy district of Minsk city. MATERIAL & METHODS: During 2011-2012 years in these regions with the help of PSA were inspected 20786 men from 50 to 65 years old without major concomitant morbidities. The algorithm of study was the following: biyearly PSA test was made in objective male population, if it was more 4 ng\ml the transrectal biopsy under ultrasound guidance was performed. In case of prostate cancer diagnosis patient was terated properly, but if the biopsy did not find cancer, patient was readmitted after 2 years. RESULTS: After 2 years of study PSA was analyzed in 93.4% of men included in screening programme. In 1128 (5.4%) PSA exceeded 4 ng\ml. In 249 (1.2%) men prostate cancer was diagnosed. So we can coclude, that adenocarcinoma was revealed in 1 out of 83 men 50-65 years old. During programme 1 and 2 stage cancers were find in 60.5% of men, that is much higher comparing to rest of the country (42.5%). On other hand, metastatic cancer was discovered in 7.5% of patients, but at the same time this mid republic parameter is 18.6%. For example, in Molodechno region 4 stage of cancer during screening was not find at all. Special radical treatment was undertaken for 96.6% of patients from screening programme – in republic this figure is about 30%. During the 3 years of followup in screening programme no patients died.
CONCLUSIONS: First results of pilot prostate cancer screening programme makes us to increase our efforts in spreading this project in other regions in our country. Eur Urol Suppl 2014; 13(2): e1185
e1185
National Center of Oncology and Medical Radiology, Director, Minsk, Belarus, 2National Center of Oncology and Medical Radiology, Vice-Director, Minsk, Belarus, 3Minsk Regional Hospital, Dept. of Urology 1, Minsk, Belarus INTRODUCTION & OBJECTIVES: Prostate cancer screening is one of the most discussed questions in modern oncourology. There are supporters and opponents of screening programmes who represents their arguments based on different studies. The problem of prostate cancer in Belarus became very acute. This pathology has gained all features of socially significant disease. At first, because during last 10 years we see the 27,9% growth of morbidity among men that exceeds such parameter for lung and skin cancers. At second, due to late diagnosis more then 50% of new cases of prostate cancer are revealed on 3-4 stages, when radical treatment can not be applied. The main objective of our study is to analyze the effectiveness of screening programme at example of 3 regions: towns - Soligorsk and Molodechno and Pervomayskiy district of Minsk city. MATERIAL & METHODS: During 2011-2012 years in these regions with the help of PSA were inspected 20786 men from 50 to 65 years old without major concomitant morbidities. The algorithm of study was the following: biyearly PSA test was made in objective male population, if it was more 4 ng\ml the transrectal biopsy under ultrasound guidance was performed. In case of prostate cancer diagnosis patient was terated properly, but if the biopsy did not find cancer, patient was readmitted after 2 years. RESULTS: After 2 years of study PSA was analyzed in 93.4% of men included in screening programme. In 1128 (5.4%) PSA exceeded 4 ng\ml. In 249 (1.2%) men prostate cancer was diagnosed. So we can coclude, that adenocarcinoma was revealed in 1 out of 83 men 50-65 years old. During programme 1 and 2 stage cancers were find in 60.5% of men, that is much higher comparing to rest of the country (42.5%). On other hand, metastatic cancer was discovered in 7.5% of patients, but at the same time this mid republic parameter is 18.6%. For example, in Molodechno region 4 stage of cancer during screening was not find at all. Special radical treatment was undertaken for 96.6% of patients from screening programme – in republic this figure is about 30%. During the 3 years of followup in screening programme no patients died.
CONCLUSIONS: First results of pilot prostate cancer screening programme makes us to increase our efforts in spreading this project in other regions in our country. Eur Urol Suppl 2014; 13(2): e1185
e1185