Food dependent exercise induced anaphylaxis caused by cauliflower

Food dependent exercise induced anaphylaxis caused by cauliflower

S318 Abstracts 1173 Food Dependent Exercise Induced Anaphylaxis Caused by Cauliflower: First Case Report in China TUESDAY J. Yin, H. Li; Departmen...

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S318 Abstracts

1173

Food Dependent Exercise Induced Anaphylaxis Caused by Cauliflower: First Case Report in China

TUESDAY

J. Yin, H. Li; Department of Allergy, Peking Union Medical College Hospital, Beijing, CHINA. RATIONALE: Food dependent exercise induced anaphylaxis (FDEIAn) have been studied in western countries, but no case report have been published in China. METHODS: We report a 16 year-old boy with no family or personal history of allergic disease experienced an anaphylactic reaction of urticaria, facial angioedema, throat swelling, dyspnea, syncope and hypotension while playing badminton 5 minutes after eating rice, cauliflower and pork. He recovered within 30 minutes after the emergency treatment. The intradermal skin tests to 40 kinds of food and inhaler allergens were performed; The serum total IgE and specific IgE were detected by using the UniCAP specific IgE method. The food challenge test was not taken because the parents of the boy refused it. RESULTS: Skin tests were positive to peanut, soybean, sesame, maize, artimisia pollen and negative to rice, pork, beef, chicken, wheat, shrimp, sea fish, sea crab, egg as well as milk. The total serum IgE was 814ku/l; specific IgE were: cauliflower 4.47ku/l, peanut 7.27ku/l, sesame 1.55ku/l, soybean 1.14ku/l, maize 2.54ku/l and artimisia vulgaris 7.52ku/l. Specific IgE to egg, milk, shrimp, pork, beef, mutton and chicken were negative. Under our follow-up observation of 3 years, the boy’s episodes have been prevented successfully by avoidance of cauliflower ingestion in relation to exercise. CONCLUSION: It is useful to test both in vivo and in vitro an extensive panel of foods. Avoidance of foods associated with skin test or RAST positively for hours before exercise can prevent further episodes with specific FDEIAn. This is the first case report of FDEIAn caused by cauliflower in China. Funding: Self-funded

J ALLERGY CLIN IMMUNOL FEBRUARY 2004