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Free radicals, cell damage and disease
Free Radical Biology & Medicine, Vol. 5, pp. 51-53, 1988 Printed in the USA. All rights reserved.
0891-5849/88 $3.00 + .00 © 1988 Pergamon Press pie
- ~ BookReviews FREE RADICALS, CELL DAMAGE AND DISEASE CATHERINE RICE-EVANS, E d i t o r The Richelieu Press, London, 19086. Price: $48.00 Reviewed by WilliamA. Pryor BiodynamicsInstitute, LouisianaState University,BatonRouge, LA 70803-1800, USA group on the role that radicals play in tumor initiation and progression. A section on ethanol-induced cell damage includes chapters by Peters et al., Fink et al., Albano et al., Clemens and Einsele, and Burdon. A variety of topics involving radical production during the metabolism of ethanol, plasma markers of ethanol intoxication, and the induction of protein synthesis is reviewed. All of the chapters are well-done and this section provides a mini-symposium on an important topic that has not been treated extensively in print. Oxyradicals and red blood cell pathology, the next section, includes chapters by Rice-Evans et al., Hochstein and Rice-Evans, D'Aquino and Rice-Evans, Poli et al., and Buffington et al. Here also, unique original material is published and/or similar chapters are grouped together so as to provide a very useful section. There are chapters on sickle cell pathology, G6PD deficiency, favism, thalassemia, and malaria. The final section involves chapters on a variety of diseases and conditions that may involve radicals. Included are chapters by Fuller and Green on storage of organs at low temperatures, by Lunec et al. on radicalaltered IgG and its interaction with a rheumatoid factor, and by Mitchell et al. on trace elements and motor neurone disease. Also included is a chapter on Parkinson's disease by Poirier et al. and one on GSH levels in human mammary gland by Atroshi and Westermarck. All-in-all, Dr. Rice-Evans should be congratulated on her dedication in continuing to make these volumes available for those of us that have found it impossible to attend the SFRR meeting. The variety of topics covered and the fact that many of these topics have not been the subject of symposium volumes before makes this particular volume especially useful. There is a list of participants (which I would have found more helpful had it included complete addresses) as well as a brief subject index.
This is one of a series of volumes edited by Dr. RiceEvans, volumes that are proceedings of the annual Winter meeting of the Society for Free Radical Research. This particular volume results from the December 1985 meeting held at the Royal Free Hospital in London. I have found all of these volumes useful additions to my shelf of symposium volumes on free radical biology, and this one is no exception. The problem with many volumes of this type is that fundamental articles often are re-published in established journals and so there is some redundancy. However, I find that symposium volumes can contain review articles and/ or discussion that give the reader instant access to an up-to-date view of the current status of a field. This volume contains several reviews that I found useful and unique. Furthermore, papers on a particular topic are grouped together, and this also provides a crosssection and view of a field, as viewed by a collection of experts working in that area. There are five main sections in this volume, each of substantial length. The first deals with iron and lipid peroxidation and includes chapters by Aust and White, O'Connell et al., Gutteridge et al., and Hoepelman et al. I found all four of these chapters to be useful, even though some aspects of some of them have appeared elsewhere; the collection of the data in one volume, and the ideas that are stimulated by having these articles grouped together, gives the section considerable value. The second section describes radical involvement in cancer and includes chapters by Slater et al. and Dianzani and Poli. Both these chapters are valuable contributions and contain material that, to my knowledge, has not appeared elsewhere. The publication by Trevor Slater and his very large group of co-authors is particularly useful since it organizes a great deal of facinating evidence that has been accumulated by that
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0891-5849/88 $3.00 + .00 © 1988 Pergamon Press pie
- ~ BookReviews FREE RADICALS, CELL DAMAGE AND DISEASE CATHERINE RICE-EVANS, E d i t o r The Richelieu Press, London, 19086. Price: $48.00 Reviewed by WilliamA. Pryor BiodynamicsInstitute, LouisianaState University,BatonRouge, LA 70803-1800, USA group on the role that radicals play in tumor initiation and progression. A section on ethanol-induced cell damage includes chapters by Peters et al., Fink et al., Albano et al., Clemens and Einsele, and Burdon. A variety of topics involving radical production during the metabolism of ethanol, plasma markers of ethanol intoxication, and the induction of protein synthesis is reviewed. All of the chapters are well-done and this section provides a mini-symposium on an important topic that has not been treated extensively in print. Oxyradicals and red blood cell pathology, the next section, includes chapters by Rice-Evans et al., Hochstein and Rice-Evans, D'Aquino and Rice-Evans, Poli et al., and Buffington et al. Here also, unique original material is published and/or similar chapters are grouped together so as to provide a very useful section. There are chapters on sickle cell pathology, G6PD deficiency, favism, thalassemia, and malaria. The final section involves chapters on a variety of diseases and conditions that may involve radicals. Included are chapters by Fuller and Green on storage of organs at low temperatures, by Lunec et al. on radicalaltered IgG and its interaction with a rheumatoid factor, and by Mitchell et al. on trace elements and motor neurone disease. Also included is a chapter on Parkinson's disease by Poirier et al. and one on GSH levels in human mammary gland by Atroshi and Westermarck. All-in-all, Dr. Rice-Evans should be congratulated on her dedication in continuing to make these volumes available for those of us that have found it impossible to attend the SFRR meeting. The variety of topics covered and the fact that many of these topics have not been the subject of symposium volumes before makes this particular volume especially useful. There is a list of participants (which I would have found more helpful had it included complete addresses) as well as a brief subject index.
This is one of a series of volumes edited by Dr. RiceEvans, volumes that are proceedings of the annual Winter meeting of the Society for Free Radical Research. This particular volume results from the December 1985 meeting held at the Royal Free Hospital in London. I have found all of these volumes useful additions to my shelf of symposium volumes on free radical biology, and this one is no exception. The problem with many volumes of this type is that fundamental articles often are re-published in established journals and so there is some redundancy. However, I find that symposium volumes can contain review articles and/ or discussion that give the reader instant access to an up-to-date view of the current status of a field. This volume contains several reviews that I found useful and unique. Furthermore, papers on a particular topic are grouped together, and this also provides a crosssection and view of a field, as viewed by a collection of experts working in that area. There are five main sections in this volume, each of substantial length. The first deals with iron and lipid peroxidation and includes chapters by Aust and White, O'Connell et al., Gutteridge et al., and Hoepelman et al. I found all four of these chapters to be useful, even though some aspects of some of them have appeared elsewhere; the collection of the data in one volume, and the ideas that are stimulated by having these articles grouped together, gives the section considerable value. The second section describes radical involvement in cancer and includes chapters by Slater et al. and Dianzani and Poli. Both these chapters are valuable contributions and contain material that, to my knowledge, has not appeared elsewhere. The publication by Trevor Slater and his very large group of co-authors is particularly useful since it organizes a great deal of facinating evidence that has been accumulated by that
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