Prevalence Analysis of Risk Factors on Aneurysmal Subarachnoid Hemorrhage

Prevalence Analysis of Risk Factors on Aneurysmal Subarachnoid Hemorrhage

October 2010, Vol 138, No. 4_MeetingAbstracts Poster Presentations: Tuesday, November 2, 2010 | October 2010 Frequency/Prevalence Analysis of Risk Fa...

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October 2010, Vol 138, No. 4_MeetingAbstracts Poster Presentations: Tuesday, November 2, 2010 | October 2010

Frequency/Prevalence Analysis of Risk Factors on Aneurysmal Subarachnoid Hemorrhage Sergio K. Macedo; Carlos Mauricio P. Siqueira; Sávio B. Siqueira; Rodrigo M. Nuss; Lucas C. Dias; Andre C. Souza; Gabriel V. Pereira Sao José Avaí Hospital, Itaperuna, Brazil Chest. 2010;138(4_MeetingAbstracts):229A. doi:10.1378/chest.10983 Abstract PURPOSE: The purpose of this study is frequency/prevalence analysis of risk factors on aneurysmal subarachnoid hemorrhage. METHODS: After institutional approval and informed consent,this prospective observational study took place from April 2008 to November 2009,involved all adult patients with spontaneous SAH admitted on ICU,evaluating the frequency/prevalence of some factors as:Gender,Age,Skin Color,Arterial Hypertension(AH),SmokingHabit,Diabetes Mellitus(DM),Alcoholism,Dyslipidemia,Sedentary and Use of Oral Contraceptive Method. RESULTS: There were observed a total of 128 patients(n), average age of 55,3 y-old, and obtained as main results of frequency with respective confidence intervals(CI): Gender F 73,4%(94)-(IC)64,9-80,9 M 26,6% (34)-(IC)19,1-35,1; Skin Color: White 46,2%(54)-(IC)36,955,6 Black 24,8%(29)-(IC)17,3-33,6 Brown 29,1%(34)-(IC)21,0-38,2;AH Yes 72,7%(93)(IC)64,1-80,5 No 27,3%(35)-(IC)19,8-35,9; Smoking Habit Yes 44,5%(57)-(IC)35,7-53,6 No55,5%(71)-(IC)46,4-64,3; Diabetes Mellitus: Yes 14,8%(19)-(IC)9,2-22,2 No 85,2%(109)(IC)77,8-90,8; AlcoholismYes 12,6%(16)-(IC)7,4-19,7 No 87,4%(111)-(IC)87,4-92,6; Dyslipidemia Yes 10,9%(14)-(IC)6,1-17,7 No 89,1%(114)-(IC)82,3-93,9; Sedentary Yes 25,8%(33)-(IC)18,5-34,3 No 74,2%(95)-(IC)65,6-81,5; Obesity Yes 11,7%(15)-(IC)6,7-18,6 No 88,3%(113)-(IC)81,4-93,3; Oral Contraceptive Method* Yes 5,3%(5)-(IC)1,7-12,0 No 94,7%(89)(IC)88,0-98,3. * Analysis obtained only for female gender population. CONCLUSION: We can show that among all RF, F Gender, AH and Smoking Habit had greatest prevalence index; the factor Skin Color had wide distribution from its variants; other RF as DM, Alcoholism, Dyslipidemia, Sedentary, and Use of Oral Contraceptives had not obtained significant prevalence on patients with aneurysmal SAH. CLINICAL IMPLICATIONS: Subarachnoid hemorrhage (SAH) is a catastrophic clinical event in which 2/3 of spontaneous SAH are characterized by rupture and bleeding of cerebral aneurysm. DISCLOSURE: Sergio Macedo, No Financial Disclosure Information; No Product/Research Disclosure Information 12:45 PM - 2:00 PM