E904 JACC March 12, 2013 Volume 61, Issue 10
Imaging Fully Automated Quantification of Left Ventricular and Left Atrial Volumes from Transthoracic 3D Echocardiography: A Validation Study Moderated Poster Contributions Poster Sessions, Expo North Saturday, March 09, 2013, 3:45 p.m.-4:30 p.m.
Session Title: Imaging: 3D Echocardiography Abstract Category: 18. Imaging: Echo Presentation Number: 1180M-335 Authors: Wendy Tsang, Ivan S. Salgo, Lyubomir Zarochev, Scott Settlemier, Nicole Bhave, Juergen Weese, Irina Waechter-Stehle, Michael Cardinale, Aldo Prado, Lynn Weinert, Amit R. Patel, Roberto M. Lang, University of Chicago Medical Center, Chicago, IL, USA Background: Cardiac chamber quantification from 3D transthoracic echocardiography (3D TTE) has been shown to be superior to measurements obtained from 2D studies. However, integration of 3D TTE into routine clinical practice has been limited by the time-consuming workflow and need for 3D expertise. We assessed the feasibility and accuracy of a fully automated algorithm that quantifies left atrial (LA) and left ventricular (LV) volumes and ejection fractions (EFs) from 3D TTE without human interaction. Methods: 114 patients (68 training; 46 test group) undergoing clinically indicated cardiac MRIs were prospectively recruited to have a TTE study (X5-1, Philips, USA). Multi-beat, wide-angle 3D datasets covering the LA and LV were acquired. LA and LV volumes and EFs were obtained from the 3D TTE using an automated program, which did not require any manual contour interaction (FIGURE). MRI was the reference standard. Pearson’s correlation and Bland-Altman analyses were performed. Results: Automated quantification was possible in all patients without manual intervention and required less than 5 seconds. Four patients were excluded due to poor image quality. Correlation of LA and LV chamber measurements to MRI values were excellent (TABLE). Conclusions: Rapid and accurate automated quantification of LA and LV volumes and EFs is feasible in the majority of patients and does not require specialized 3D TTE training. This technique promises to improve integration of 3D TTE into routine clinical practice.