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Further investigations on experimental atherosclerosis
124
THE
John:
Parkinson,
AMEfUCAN
Enlargement
Hl5AR.T
of the Heart.
JOURNAL
Lancet 1: 1337, 1936.
This subject was presented as the Lumleian Lectures for 1936, delivered before the Royal College of Physicians in London. It is an extensive review of the well-known facts of heart size and concepts of those influences which change this size, either in the whole heart or in particular regions. This is a full review of the accepted methods of studying cardiac enlargement and considerable emphasis is placed on radiological methods. Little mention is made of palpation in determining cardiac size. The article contains considerable information from the author’s own experiences, particularly his analysis of the work of others which has been done under his direction. and tion
The determination of the size of the one which is not yet fully explained. to the subject.
heart still remains an interesting This article is an interesting
subject contribuH.
McC.
Clark, Eugene, and Berger, Adolph R,: Hemorrhagic Extravasations Into the Leaflets of the Atrioventricular Valves: Their Relationship to PuImonary Embolism. Arch. Path. 22: 524, 1936. Rcchymoses in noninflamed atrioventricular valvular leaflets were observed in four persons. In three who showed pulmonary embolism, the eechymoses were limited to leaflets of the tricuspid valve. In the fourth, hemorrhages occurred beneath the mural endocardium and in the leaflets of the mitral and tricuspid valves. In all four, some of the ecchymoses involved the vaseularized annuli, whereas others were limited to the distal, apparently avascular, regions of the leaffets, It is suggested that the ecchymoses which were limited to the leaflets of the tricuspid valve were related to the coexisting pulmonary embolism. AUTHOR, Infection in Childhood: ObservaStruthers, R., I%., and Bacal, II. L.: Rheumatic tions on the Sedimentation Rate and the Schilling Count. Canad. M. A. J. 35: 258,
1936.
Observations on 100 cases of rheumatic infection in childhood indicate that the sedimentation rate is a more satisfactory test for the activity of rheumatic infection than is the Schilling differential count. It has also the advantage of simplicity: it is not laborious, and it does not require speeial technical training. The sedimentation rate is also of greater sensitivity as an index of inactivity of rheumatic infection. H. McC.
James W., and Meeker, mental Atherosclerosis. Arch.
Jobling,
Dorothy Path.
22:
R.: 293,
Further
Investigations
on Experi-
1936.
An unsuccessful attempt was made to accelerate and increase the develop ment of cholesterol lesions in the aorta of the rabbit by the following injurious procedures added to cholesterol feeding: (1) intravenous injections of streptococcus toxin, (2) ammonium chloride feeding, (3) production of artificial fever, (4) intravenous injections of peptone, (5) induction of anaphylactic shock, and (6) intravenous injections of uric acid. Similarly, no effect on the blood vessels of cats could be demonstrated they were fed cholesterol and, in addition, were treated with (1) peptone histamine intravenously or were fed (3) ammonium chloride.
or
when (2)
Aurnos.
THE
John:
Parkinson,
AMEfUCAN
Enlargement
Hl5AR.T
of the Heart.
JOURNAL
Lancet 1: 1337, 1936.
This subject was presented as the Lumleian Lectures for 1936, delivered before the Royal College of Physicians in London. It is an extensive review of the well-known facts of heart size and concepts of those influences which change this size, either in the whole heart or in particular regions. This is a full review of the accepted methods of studying cardiac enlargement and considerable emphasis is placed on radiological methods. Little mention is made of palpation in determining cardiac size. The article contains considerable information from the author’s own experiences, particularly his analysis of the work of others which has been done under his direction. and tion
The determination of the size of the one which is not yet fully explained. to the subject.
heart still remains an interesting This article is an interesting
subject contribuH.
McC.
Clark, Eugene, and Berger, Adolph R,: Hemorrhagic Extravasations Into the Leaflets of the Atrioventricular Valves: Their Relationship to PuImonary Embolism. Arch. Path. 22: 524, 1936. Rcchymoses in noninflamed atrioventricular valvular leaflets were observed in four persons. In three who showed pulmonary embolism, the eechymoses were limited to leaflets of the tricuspid valve. In the fourth, hemorrhages occurred beneath the mural endocardium and in the leaflets of the mitral and tricuspid valves. In all four, some of the ecchymoses involved the vaseularized annuli, whereas others were limited to the distal, apparently avascular, regions of the leaffets, It is suggested that the ecchymoses which were limited to the leaflets of the tricuspid valve were related to the coexisting pulmonary embolism. AUTHOR, Infection in Childhood: ObservaStruthers, R., I%., and Bacal, II. L.: Rheumatic tions on the Sedimentation Rate and the Schilling Count. Canad. M. A. J. 35: 258,
1936.
Observations on 100 cases of rheumatic infection in childhood indicate that the sedimentation rate is a more satisfactory test for the activity of rheumatic infection than is the Schilling differential count. It has also the advantage of simplicity: it is not laborious, and it does not require speeial technical training. The sedimentation rate is also of greater sensitivity as an index of inactivity of rheumatic infection. H. McC.
James W., and Meeker, mental Atherosclerosis. Arch.
Jobling,
Dorothy Path.
22:
R.: 293,
Further
Investigations
on Experi-
1936.
An unsuccessful attempt was made to accelerate and increase the develop ment of cholesterol lesions in the aorta of the rabbit by the following injurious procedures added to cholesterol feeding: (1) intravenous injections of streptococcus toxin, (2) ammonium chloride feeding, (3) production of artificial fever, (4) intravenous injections of peptone, (5) induction of anaphylactic shock, and (6) intravenous injections of uric acid. Similarly, no effect on the blood vessels of cats could be demonstrated they were fed cholesterol and, in addition, were treated with (1) peptone histamine intravenously or were fed (3) ammonium chloride.
or
when (2)
Aurnos.