Further observations on gonococcal vulvovaginitis

Department

of Reviews Selected

and Abstracts _--__-

Abstracts

Gonorrhea East, E.

N.:

Gonorrhea

in the

Female, Canad.

M.

A. J. 45:

250, 1941.

Six hundred and twenty-six cases of gonorrhea were found in 1,712 women presenting themselves to the Vancouver Venereal Disease Control Clinic. Diagnosis was based on smear and culture. Trichomonas infections were present in 20 per cent of the cases. Rectal gonorrhea was diagnosed in only 8 cases. Sixty-four per cent were cured on sulfanilamide therapy alone. Pelvic complications were present in 9.2 per cent of the cases. Final cure was based on smear and culture examinations one month after apparent clinical cure.

P.

CARL

BuBER

Hesseltine, II. Close, Hat, Lucile R., Adair, Fred L., and Hibbs, Donald IF.: Prelimiuarg Report of Sulfanilamide, Sulfapyridine, and Local Therapy in -nococcal Infection in Women, Am. J. Qph., Gonor. & Ven. Dis. 25: 454, 1941. Of 41 patients on local treatment, 8 (20 per cent) were cured and 33 (80 per cent) were not cured. Seventeen of the failures were shifted to chemotherapy, to which 16 responded; the 1 failure gave evidence of reinfection. Of

the

46 patients on sulfanilamide therapy, 32 (70 per cent) were cured and cent) were not cured. Of t.he 14 not cured, 6 (43 per cent) showed of reinfection; 8 (57 per cent) showed no evidence of reinfection; the drug failure was 17 per cent for this series.

14 (30 per evidence probable

Of the 63 patients on sulfapyridine, 45 (71 per cent) were cured and 18 (29 per cent) were not cured. Of the 18 not cured, 14 (77 per cent) showed evidence of reinfection ; 4 showed no evidence of reinfection; the probable drug failure was 6 per cent for this series. Chemotherapy

is superior

to local

measures

in the treatment

of gonococcal infec:

tion in women. With sulfapyridine treatment is shorter, of failures is lower, sulfanilamide.

therapy in gonococcal infection of women, the duration of the dosage is smaller, the response is quicker, the percentage and the patient complains lese of toxic symptoms than with C.

0.

MALAND

Brundu, Carlo: A Brief Note About Sulfonamide Therapy and Gimosulfonamides in Blenorrhagic Infections, Especially in the Female, Rassegna d’ostet. e ginec. 48: 394, 1939. The author presents and discusses a new sulfonamide bination of methylene blue and sulfonamide. It is said the armamentarium in antiblenorrhagic therapy. 172

preparation. to be a valuable

It

is a comaddition to