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G-protein coupled receptors
JOURNAL OF VASCULAR SURGERY December 2001
1138 Book Reviews
For readers interested in setting up a phlebology practice, there is a complete appendix that presents forms, sources of equipment, and a very welcome section on terminology of venous diagnosis and treatment as well as the current CPT codes. This is a welcome volume, a comprehensive resource, and a well-illustrated presentation on a very important topic. John J. Bergan, MD La Jolla, Calif doi:10.1067/mva.2001.116308
G-protein coupled receptors Tatsuya Haga, Gabriel Berstein; Boca Raton; 2000; CRC Press; 398 pages. This present book is part of the series of the CRC methods in signal transduction, which has as its goal to bring together the wealth of methodology now available for the research in many aspects of signal transduction. The book is split into three sections. The first describes novel ligands, ligand-screening systems, and orphan receptors. The second examines function and regulation, receptor G-protein coupling, and desensitization, and the
third examines three-dimensional structure, in particular, largescale expression and electron and x-ray crystallography. The two editors have assembled a representative panel of contributors. The book covers the area well, but it is a hard read with detailed methods interspersed between the standard text. Despite this shortcoming, the book will act as an excellent source of primary methodology for nonvascular cell studies and G-protein signal transduction and should be of help to those interested in particular technical aspects of this enterprise. For vascular biologists, the book does not cover issues with regard to vascular signal transduction and its application in the various cardiovascular disease states. The book is not written as a primer or review of Gprotein coupled receptors. Therefore, although it is a very good review of primary techniques and methodology, I believe it would not be of significant interest to the readers of the Journal of Vascular Surgery, but I would endorse it as an aid to those who are struggling with the technical aspects of signal transduction in immortalized cell lines. Mark G. Davies, MD, PhD University of Rochester Medical School Rochester, NY doi:10.1067/mva.2001.117450
1138 Book Reviews
For readers interested in setting up a phlebology practice, there is a complete appendix that presents forms, sources of equipment, and a very welcome section on terminology of venous diagnosis and treatment as well as the current CPT codes. This is a welcome volume, a comprehensive resource, and a well-illustrated presentation on a very important topic. John J. Bergan, MD La Jolla, Calif doi:10.1067/mva.2001.116308
G-protein coupled receptors Tatsuya Haga, Gabriel Berstein; Boca Raton; 2000; CRC Press; 398 pages. This present book is part of the series of the CRC methods in signal transduction, which has as its goal to bring together the wealth of methodology now available for the research in many aspects of signal transduction. The book is split into three sections. The first describes novel ligands, ligand-screening systems, and orphan receptors. The second examines function and regulation, receptor G-protein coupling, and desensitization, and the
third examines three-dimensional structure, in particular, largescale expression and electron and x-ray crystallography. The two editors have assembled a representative panel of contributors. The book covers the area well, but it is a hard read with detailed methods interspersed between the standard text. Despite this shortcoming, the book will act as an excellent source of primary methodology for nonvascular cell studies and G-protein signal transduction and should be of help to those interested in particular technical aspects of this enterprise. For vascular biologists, the book does not cover issues with regard to vascular signal transduction and its application in the various cardiovascular disease states. The book is not written as a primer or review of Gprotein coupled receptors. Therefore, although it is a very good review of primary techniques and methodology, I believe it would not be of significant interest to the readers of the Journal of Vascular Surgery, but I would endorse it as an aid to those who are struggling with the technical aspects of signal transduction in immortalized cell lines. Mark G. Davies, MD, PhD University of Rochester Medical School Rochester, NY doi:10.1067/mva.2001.117450