- Email: [email protected]
GIANT CELL FIBROMA: A CASE REPORT
OOOO Volume 129, Number 1 CD68; a negative result for creatine kinase, M type (CKM), CD31, CD 34, p63, S100, smooth muscle actin (SMA), human herpesvirus 8 (HHV-8), desmin, and proliferative index (Ki-67) of 10%. A final diagnosis of benign fibrous histiocytoma was concluded. The healing process was uneventful and no recurrence was observed during 14 months of follow-up.
GIANT CELL FIBROMA: A CASE REPORT. e MANUELLA BRAUN DE OLIVEIRA ESPANA, e ANDRESSA SALOMAO LOPES, FABIO ^ PIRES, WAGNER PINTO DAS CHAGAS, THAIS RAMOA e PIMENTEL, NATHALIA ALMEIDA and, MONICA SIMOES ISRAEL Giant cell fibroma (GCF) is an asymptomatic nodular mass lesion, sessile or pediculated, generally with a diameter equal or smaller than 1 cm. GCF is often related to young patients, and the gingiva is the most affected site, but it may occur in the palate and tongue. This is a report of case of a GCF arising in a 42-year-old white female patient presenting with a lesion in the anterior gingiva, with an evolution of 7 years. During the clinical examination, a nodule was observed between the upper central and lateral incisors. Diagnostic hypotheses were peripheral ossifying fibroma and fibrous hyperplasia. An excisional biopsy was performed. According to the histopathologic patterns, a diagnosis of giant cell fibroma was made. The patient underwent clinical reexamination and after 1 year there was no evidence of a recurrence.
PHOTODYNAMIC THERAPY FOR BISPHOSPHONATE-RELATED OSTEONECROSIS IN PALATINE TORUS: A CASE REPORT. GIULIANNA LIMA PINHEIRO, WAGNER PINTO DAS CHAGAS, NATHALIA DE ALMEIDA FREIRE, MARCO PONTES, ROSEMIRO DE MENEZES MACIEL, ^ e MARIA ELIZA BARBOSA RAMOS and, MONICA SIMOES ISRAEL Bisphosphonates (BPs) are widely used as first-line therapy for osteoporosis or metastasis of malignant neoplasms to bone. However, one of the severe late complications of the long-time use of BPs is bisphosphonate-related osteonecrosis of the jaw (BRONJ). Osteonecrosis of the jaws can affect quality of life because of feeding limitations and intense pain. This case report demonstrates the use of photodynamic therapy (PDT) in a bisphosphonate-related lesion, in a 75-year-old female who used alendronate for 7 years. Clinical examination revealed a firm lesion with ulcerated center, about 3 cm, located in the hard palate. The diagnostic of BRONJ was clinically established and the decision was to initiate photodynamic therapy (PDT) mediated by methylene blue. Laser treatment was provided weekly for a total of 7 treatment sessions. Follow-up examination 3 months later showed no evidence of recurrence.
ORAL ALTERATIONS IN PATIENTS WITH SPONDYLOCOSTAL DYSOSTOSIS: A CASE TUMA and, REPORT. MARINA MAUES MARINA GALLOTTINI Spondylocostal dysostosis is a rare genetic disease characterized by skeletal malformations, such as multiple segmentation defects of the vertebrae, rib misalignment with variable points of intercostal fusion, and reduction in the number of ribs. In the
ABSTRACTS
e41
literature, we did not find any reports of oral manifestations related to this condition. This is the report of a 23-year-old white woman with spondylocostal dysostosis, with short stature, short trunk and neck, prominent thorax, moderate scoliosis, umbilical hernia, and cognitive deficit. In addition, we observed nodules on the upper lip and tongue, generalized enamel hypoplasia, and gemination of the crown of tooth 32. Radiographic examination revealed presence of supernumerary teeth in the mandible and gyroversion of the tooth 31. We guided and motivated dental hygiene, performed periodontal therapy, restored the anterior teeth, and performed the endodontic treatment of the tooth 46. The aesthetic and functional rehabilitation performed proved to be effective
CLEIDOCRANIAL DYSPLASIA: 2 CASE REPORTS. CAROLINE CAVAIGNAC SILVA CARVALHO, FERNANDA HEIMLICH, NATHALIA DE ALMEIDA FREIRE, MARIA ELIZA BARBOSA RAMOS, ROSEMIRO DE MENEZES MACIEL, ^ e ISRAEL WAGNER CHAGAS and, MONICA SIMOES Known for its dental and clavicular abnormalities, cleidocranial dysplasia is a rare disorder of bones. The appearance of the patient often confirms the diagnosis: short stature; large head with pronounced frontal and parietal bossing; ocular hypertelorism; and broad base of the nose with a depressed nasal bridge. Gnathic and dental manifestations are distinctive and lead to the initial diagnosis. The patients often have a narrow, high-arched palate; prolonged retention of deciduous teeth, and delay or complete failure of eruption of permanent teeth; also present are supernumerary teeth. Two female patients, 25 and 21 years old, visited the stomatology clinic complaining about the presence of deciduous teeth. One presented with supernumeraries, an arched palate, and was characterized as brachycephalic. She reported delay in the closure of sutures. The other one had a prominent forehead. Panoramic radiographs were required. Both patients were diagnosed with cleidocranial dysplasia and referred for dental treatment.
ANAPLASTIC TUMOR OF THE ANTERIOR MAXILLA: DIFFERENTIAL DIAGNOSIS AND IMMUNOHISTOCHEMICAL STUDY. YAMILLE DE LIMA SOUZA, DIOGO HENRIQUE OHSE, ^ EDUARDO ANTONIO BARBOSA DE ANDRADE, THOMAS JEFFERSON REIS PEREIRA, LUIZ CARLOS DE LIMA FERREIRA and, TIAGO NOVAES PINHEIRO The present study reports a rare case of anaplastic malignant melanoma in a 23-year-old female patient, in the anterior maxilla. On clinical examination, the lesion presented as a 5-cm sessile nodule, with brownish irregular macules on the mucosal surface, painless, with a firm consistency ranging from teeth 14 to 24 with palatal and nasal extension causing facial asymmetry and dental mobility. The computed tomography showed irregular lytic bone reabsorption, without dental involvement. The incisional biopsy followed by microscopic examination suggested primitive neuroectodermal tumor, due to the presence of round blue cells, periodic acid-Schiff (PAS)-positive clear cells, with considerable pleomorphism, atypical mitosis, hemorrhagic areas, and coagulative necrosis. Immunohistochemistry revealed highgrade epithelioid neoplasm and a diagnosis of invasive melanoma was concluded; the melanoma was positive for S-100
GIANT CELL FIBROMA: A CASE REPORT. e MANUELLA BRAUN DE OLIVEIRA ESPANA, e ANDRESSA SALOMAO LOPES, FABIO ^ PIRES, WAGNER PINTO DAS CHAGAS, THAIS RAMOA e PIMENTEL, NATHALIA ALMEIDA and, MONICA SIMOES ISRAEL Giant cell fibroma (GCF) is an asymptomatic nodular mass lesion, sessile or pediculated, generally with a diameter equal or smaller than 1 cm. GCF is often related to young patients, and the gingiva is the most affected site, but it may occur in the palate and tongue. This is a report of case of a GCF arising in a 42-year-old white female patient presenting with a lesion in the anterior gingiva, with an evolution of 7 years. During the clinical examination, a nodule was observed between the upper central and lateral incisors. Diagnostic hypotheses were peripheral ossifying fibroma and fibrous hyperplasia. An excisional biopsy was performed. According to the histopathologic patterns, a diagnosis of giant cell fibroma was made. The patient underwent clinical reexamination and after 1 year there was no evidence of a recurrence.
PHOTODYNAMIC THERAPY FOR BISPHOSPHONATE-RELATED OSTEONECROSIS IN PALATINE TORUS: A CASE REPORT. GIULIANNA LIMA PINHEIRO, WAGNER PINTO DAS CHAGAS, NATHALIA DE ALMEIDA FREIRE, MARCO PONTES, ROSEMIRO DE MENEZES MACIEL, ^ e MARIA ELIZA BARBOSA RAMOS and, MONICA SIMOES ISRAEL Bisphosphonates (BPs) are widely used as first-line therapy for osteoporosis or metastasis of malignant neoplasms to bone. However, one of the severe late complications of the long-time use of BPs is bisphosphonate-related osteonecrosis of the jaw (BRONJ). Osteonecrosis of the jaws can affect quality of life because of feeding limitations and intense pain. This case report demonstrates the use of photodynamic therapy (PDT) in a bisphosphonate-related lesion, in a 75-year-old female who used alendronate for 7 years. Clinical examination revealed a firm lesion with ulcerated center, about 3 cm, located in the hard palate. The diagnostic of BRONJ was clinically established and the decision was to initiate photodynamic therapy (PDT) mediated by methylene blue. Laser treatment was provided weekly for a total of 7 treatment sessions. Follow-up examination 3 months later showed no evidence of recurrence.
ORAL ALTERATIONS IN PATIENTS WITH SPONDYLOCOSTAL DYSOSTOSIS: A CASE TUMA and, REPORT. MARINA MAUES MARINA GALLOTTINI Spondylocostal dysostosis is a rare genetic disease characterized by skeletal malformations, such as multiple segmentation defects of the vertebrae, rib misalignment with variable points of intercostal fusion, and reduction in the number of ribs. In the
ABSTRACTS
e41
literature, we did not find any reports of oral manifestations related to this condition. This is the report of a 23-year-old white woman with spondylocostal dysostosis, with short stature, short trunk and neck, prominent thorax, moderate scoliosis, umbilical hernia, and cognitive deficit. In addition, we observed nodules on the upper lip and tongue, generalized enamel hypoplasia, and gemination of the crown of tooth 32. Radiographic examination revealed presence of supernumerary teeth in the mandible and gyroversion of the tooth 31. We guided and motivated dental hygiene, performed periodontal therapy, restored the anterior teeth, and performed the endodontic treatment of the tooth 46. The aesthetic and functional rehabilitation performed proved to be effective
CLEIDOCRANIAL DYSPLASIA: 2 CASE REPORTS. CAROLINE CAVAIGNAC SILVA CARVALHO, FERNANDA HEIMLICH, NATHALIA DE ALMEIDA FREIRE, MARIA ELIZA BARBOSA RAMOS, ROSEMIRO DE MENEZES MACIEL, ^ e ISRAEL WAGNER CHAGAS and, MONICA SIMOES Known for its dental and clavicular abnormalities, cleidocranial dysplasia is a rare disorder of bones. The appearance of the patient often confirms the diagnosis: short stature; large head with pronounced frontal and parietal bossing; ocular hypertelorism; and broad base of the nose with a depressed nasal bridge. Gnathic and dental manifestations are distinctive and lead to the initial diagnosis. The patients often have a narrow, high-arched palate; prolonged retention of deciduous teeth, and delay or complete failure of eruption of permanent teeth; also present are supernumerary teeth. Two female patients, 25 and 21 years old, visited the stomatology clinic complaining about the presence of deciduous teeth. One presented with supernumeraries, an arched palate, and was characterized as brachycephalic. She reported delay in the closure of sutures. The other one had a prominent forehead. Panoramic radiographs were required. Both patients were diagnosed with cleidocranial dysplasia and referred for dental treatment.
ANAPLASTIC TUMOR OF THE ANTERIOR MAXILLA: DIFFERENTIAL DIAGNOSIS AND IMMUNOHISTOCHEMICAL STUDY. YAMILLE DE LIMA SOUZA, DIOGO HENRIQUE OHSE, ^ EDUARDO ANTONIO BARBOSA DE ANDRADE, THOMAS JEFFERSON REIS PEREIRA, LUIZ CARLOS DE LIMA FERREIRA and, TIAGO NOVAES PINHEIRO The present study reports a rare case of anaplastic malignant melanoma in a 23-year-old female patient, in the anterior maxilla. On clinical examination, the lesion presented as a 5-cm sessile nodule, with brownish irregular macules on the mucosal surface, painless, with a firm consistency ranging from teeth 14 to 24 with palatal and nasal extension causing facial asymmetry and dental mobility. The computed tomography showed irregular lytic bone reabsorption, without dental involvement. The incisional biopsy followed by microscopic examination suggested primitive neuroectodermal tumor, due to the presence of round blue cells, periodic acid-Schiff (PAS)-positive clear cells, with considerable pleomorphism, atypical mitosis, hemorrhagic areas, and coagulative necrosis. Immunohistochemistry revealed highgrade epithelioid neoplasm and a diagnosis of invasive melanoma was concluded; the melanoma was positive for S-100