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Giant Inflammatory Myofibroblastic Tumor of Esophagus
Giant Inflammatory Myofibroblastic Tumor of Esophagus Dianbo Cao, MD, PhD, Xiaojun Wang, MD, PhD, Hong Zhang, MD, PhD, and Liang Guo, MD Departments of Radiology, Thoracic Surgery, and Pathology, The First Hospital of Jilin University, Chang Chun, China
Fig 1.
A
Fig 2.
Address correspondence to Dr Cao, Department of Radiology, The First Hospital of Jilin University, 1 Xin Min Zhu St, Chang Chun, 130021, China; e-mail: [email protected].
© 2009 by The Society of Thoracic Surgeons Published by Elsevier Inc
55-year-old woman was admitted to our hospital with a complaint of dysphagia and weight loss for 1 year. A barium examination indicated a filling defect in the thoracic esophagus (Figs 1A and 1B), and computed tomographic chest reconstruction showed a long-column mass in the region described. An endoscopic examination revealed marked stenosis with a smooth surface and diffuse esophageal wall elevation (Fig 1C; Inset: mini-picture of Fig 1C, which was captured by endoscopy in the process of operation). An endoscopic ultrasound of the esophagus showed a submucosal heterogeneous mass with a clear margin in the thoracic esophagus. A giant neoplasm was successfully removed by opening the esophagus (Fig 2A). Microscopically, the tumor consisted of a mixture of fibroblastic cells and inflammatory cells (Fig 2B). Immunohistochemistry staining showed the tumor was positive for smooth muscle actin, and was negative for CD34, CD117, and S-100. Histology characteristic of the neoplasm supports a diagnosis of inflammatory myofibroblastic tumor. The patient recovered with an uneventful postoperative course. We believe that inflammatory myofibroblastic tumor of the esophagus similar to this case has never been reported before.
Ann Thorac Surg 2009;88:e45 • 0003-4975/09/$36.00 doi:10.1016/j.athoracsur.2009.07.073
Fig 1.
A
Fig 2.
Address correspondence to Dr Cao, Department of Radiology, The First Hospital of Jilin University, 1 Xin Min Zhu St, Chang Chun, 130021, China; e-mail: [email protected].
© 2009 by The Society of Thoracic Surgeons Published by Elsevier Inc
55-year-old woman was admitted to our hospital with a complaint of dysphagia and weight loss for 1 year. A barium examination indicated a filling defect in the thoracic esophagus (Figs 1A and 1B), and computed tomographic chest reconstruction showed a long-column mass in the region described. An endoscopic examination revealed marked stenosis with a smooth surface and diffuse esophageal wall elevation (Fig 1C; Inset: mini-picture of Fig 1C, which was captured by endoscopy in the process of operation). An endoscopic ultrasound of the esophagus showed a submucosal heterogeneous mass with a clear margin in the thoracic esophagus. A giant neoplasm was successfully removed by opening the esophagus (Fig 2A). Microscopically, the tumor consisted of a mixture of fibroblastic cells and inflammatory cells (Fig 2B). Immunohistochemistry staining showed the tumor was positive for smooth muscle actin, and was negative for CD34, CD117, and S-100. Histology characteristic of the neoplasm supports a diagnosis of inflammatory myofibroblastic tumor. The patient recovered with an uneventful postoperative course. We believe that inflammatory myofibroblastic tumor of the esophagus similar to this case has never been reported before.
Ann Thorac Surg 2009;88:e45 • 0003-4975/09/$36.00 doi:10.1016/j.athoracsur.2009.07.073