- Email: [email protected]
Giant Recurrent Sacral Chordoma
Accepted Manuscript Giant Recurrent Sacral Chordoma Linkai Jing, MD, Guihuai Wang, MD, PhD PII:
S1878-8750(18)32463-X
DOI:
https://doi.org/10.1016/j.wneu.2018.10.165
Reference:
WNEU 10609
To appear in:
World Neurosurgery
Received Date: 16 October 2018 Accepted Date: 25 October 2018
Please cite this article as: Jing L, Wang G, Giant Recurrent Sacral Chordoma, World Neurosurgery (2018), doi: https://doi.org/10.1016/j.wneu.2018.10.165. This is a PDF file of an unedited manuscript that has been accepted for publication. As a service to our customers we are providing this early version of the manuscript. The manuscript will undergo copyediting, typesetting, and review of the resulting proof before it is published in its final form. Please note that during the production process errors may be discovered which could affect the content, and all legal disclaimers that apply to the journal pertain.
ACCEPTED MANUSCRIPT 1
Title page Title: Giant Recurrent Sacral Chordoma
3
Co-authors: Linkai Jing, MD; Guihuai Wang, MD, PhD
4
Affiliations: School of Clinical Medicine, Tsinghua University, Beijing, 100084,
5
China; Department of Neurosurgery, Beijing Tsinghua Changgung Hospital, School of
6
Clinical Medicine, Tsinghua University, Beijing, 102218, China.
7
E-mail: [email protected]; [email protected].
8
Corresponding authors: Guihuai Wang. Department of Neurosurgery, Beijing
9
Tsinghua Changgung Hospital, School of Clinical Medicine, Tsinghua University,
10
Beijing, 102218, China. Email: [email protected]. Tel: + 86-01056118887.
11
Fax: + 86-010-56118500.
12
Keywords: Recurrent chordoma, Sacral chordoma, Surgery
SC
M AN U
TE D EP AC C
RI PT
2
ACCEPTED MANUSCRIPT
Giant Recurrent Sacral Chordoma A 65-year-old man presented with a giant recurrent sacral chordoma after undergoing 7 surgical resections (Panel A). Neurological examination
RI PT
revealed urinary incontinence. Magnetic resonance imaging (MRI) showed a huge mass lesion in the bilateral gluteal regions and multiple metastatic chordomas (Panel B, arrows). Colostomy and wide en bloc
SC
excision of the giant recurrent chordoma were performed in April 2017
M AN U
(Panel C and D). The tumor weighed 13.15 kg, and histopathological examination revealed a chordoma. MRI performed at the 12-month follow-up showed slight recurrence (Panel E, small arrows). Additionally, multiple metastatic chordomas localized to the pelvic cavity and the
TE D
subcutaneous layer of the gluteal region showed significant enlargement (Panel E, large arrows). The metastatic chordomas were resected in May
EP
2018. At his last follow-up, the patient presented with an indwelling catheter and a colostomy bag, and the recurrent chordoma showed no
AC C
visible enlargement (Panel F).
AC C
EP
TE D
M AN U
SC
RI PT
ACCEPTED MANUSCRIPT
ACCEPTED MANUSCRIPT
EP
TE D
M AN U
SC
RI PT
Abbreviations: MRI = magnetic resonance imaging
AC C
1
ACCEPTED MANUSCRIPT
AC C
EP
TE D
M AN U
SC
RI PT
Conflict of interest: We declare that they have no conflict of interest.
S1878-8750(18)32463-X
DOI:
https://doi.org/10.1016/j.wneu.2018.10.165
Reference:
WNEU 10609
To appear in:
World Neurosurgery
Received Date: 16 October 2018 Accepted Date: 25 October 2018
Please cite this article as: Jing L, Wang G, Giant Recurrent Sacral Chordoma, World Neurosurgery (2018), doi: https://doi.org/10.1016/j.wneu.2018.10.165. This is a PDF file of an unedited manuscript that has been accepted for publication. As a service to our customers we are providing this early version of the manuscript. The manuscript will undergo copyediting, typesetting, and review of the resulting proof before it is published in its final form. Please note that during the production process errors may be discovered which could affect the content, and all legal disclaimers that apply to the journal pertain.
ACCEPTED MANUSCRIPT 1
Title page Title: Giant Recurrent Sacral Chordoma
3
Co-authors: Linkai Jing, MD; Guihuai Wang, MD, PhD
4
Affiliations: School of Clinical Medicine, Tsinghua University, Beijing, 100084,
5
China; Department of Neurosurgery, Beijing Tsinghua Changgung Hospital, School of
6
Clinical Medicine, Tsinghua University, Beijing, 102218, China.
7
E-mail: [email protected]; [email protected].
8
Corresponding authors: Guihuai Wang. Department of Neurosurgery, Beijing
9
Tsinghua Changgung Hospital, School of Clinical Medicine, Tsinghua University,
10
Beijing, 102218, China. Email: [email protected]. Tel: + 86-01056118887.
11
Fax: + 86-010-56118500.
12
Keywords: Recurrent chordoma, Sacral chordoma, Surgery
SC
M AN U
TE D EP AC C
RI PT
2
ACCEPTED MANUSCRIPT
Giant Recurrent Sacral Chordoma A 65-year-old man presented with a giant recurrent sacral chordoma after undergoing 7 surgical resections (Panel A). Neurological examination
RI PT
revealed urinary incontinence. Magnetic resonance imaging (MRI) showed a huge mass lesion in the bilateral gluteal regions and multiple metastatic chordomas (Panel B, arrows). Colostomy and wide en bloc
SC
excision of the giant recurrent chordoma were performed in April 2017
M AN U
(Panel C and D). The tumor weighed 13.15 kg, and histopathological examination revealed a chordoma. MRI performed at the 12-month follow-up showed slight recurrence (Panel E, small arrows). Additionally, multiple metastatic chordomas localized to the pelvic cavity and the
TE D
subcutaneous layer of the gluteal region showed significant enlargement (Panel E, large arrows). The metastatic chordomas were resected in May
EP
2018. At his last follow-up, the patient presented with an indwelling catheter and a colostomy bag, and the recurrent chordoma showed no
AC C
visible enlargement (Panel F).
AC C
EP
TE D
M AN U
SC
RI PT
ACCEPTED MANUSCRIPT
ACCEPTED MANUSCRIPT
EP
TE D
M AN U
SC
RI PT
Abbreviations: MRI = magnetic resonance imaging
AC C
1
ACCEPTED MANUSCRIPT
AC C
EP
TE D
M AN U
SC
RI PT
Conflict of interest: We declare that they have no conflict of interest.