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Gradient liquid chromatography
Jouwal of Chronratograplry. 107 (1975) 239 0 Elscvier Scientific Publishing Company,
CHROM.
Book
Amsterdam
-
Printed
in
The Netherlands
8105
Review
Gradient liquid chromatography,
Chichester, (distributed 338 pp., price f10.50.
by C. Liteanu and S. Gocan. Ellis Horwood Ltd., by Wiley, Chichester and New York), 1974, Xl11 -t-
At a time when there is a considerable revival of interest in liquid chromatography, it would be quite understandable to expect this book to deal only with the latest aspects of the technique. In fact. the text covers all forms of liquid phase separations, both closed-column and open-column techniques, such as thin-layer and,pa,per chromatography. The main emphasis of the book is to explain in detail the mechanism and procedures by which liquid phase separations are performed. The explanation covers both non-gradient and gradient methods. Part 1 of the book (12 1 pages) deals almost exclusively with the former technique. The approach taken by the authors is to present a fairly rigorous theoretical treatment with considerable use of equations. The tone of the text is such that it would be difficult for any beginner in liquid chromatography to follow the arguments: this is made worse by the text containing many references to other work -over 900 in the entire book. The large number of references could make the text a useful guide to the literature, however, in some instances the number seems excessive. This impression is typified by Chapter 3, where 179 references are cited in a chapter only eleven pages long. Although the publication date is 1974, references to literature published after 1970 are very few indeed. A survey of the literature cited indicates approximately 15 publications dated 1971 and even less for 1972, of which the latter refer almost exclusively to work of the authors. This apparent lack of up-to-date information is also reflected in the text, notably in the sections dealing with the optimisation of chromatographic performance, where there is hardly a mention of the current emphasis being placed on the use of column packings of less than 10-p diameter. Similarly, the description of apparatus for gradient elution, which is particularly detailed, fails to mention equipment introduced commercially over the last four years. Appendix 1 attempts to overcome this omission by listing the companies offering equipment for gradient liquid chromatography. On the other hand, considerable space is devoted to describing the construction of apparatus, particularly for use with paper and thinlayer techniques. The text contains considerable detail which could be of value to those wishing to understand or optimise gradient procedures. To derive the maximum benefit from the book, however, it would need to be studied rather than read. Letckworth
(Great Britaitl)
NORMAN
A. PARRIS
CHROM.
Book
Amsterdam
-
Printed
in
The Netherlands
8105
Review
Gradient liquid chromatography,
Chichester, (distributed 338 pp., price f10.50.
by C. Liteanu and S. Gocan. Ellis Horwood Ltd., by Wiley, Chichester and New York), 1974, Xl11 -t-
At a time when there is a considerable revival of interest in liquid chromatography, it would be quite understandable to expect this book to deal only with the latest aspects of the technique. In fact. the text covers all forms of liquid phase separations, both closed-column and open-column techniques, such as thin-layer and,pa,per chromatography. The main emphasis of the book is to explain in detail the mechanism and procedures by which liquid phase separations are performed. The explanation covers both non-gradient and gradient methods. Part 1 of the book (12 1 pages) deals almost exclusively with the former technique. The approach taken by the authors is to present a fairly rigorous theoretical treatment with considerable use of equations. The tone of the text is such that it would be difficult for any beginner in liquid chromatography to follow the arguments: this is made worse by the text containing many references to other work -over 900 in the entire book. The large number of references could make the text a useful guide to the literature, however, in some instances the number seems excessive. This impression is typified by Chapter 3, where 179 references are cited in a chapter only eleven pages long. Although the publication date is 1974, references to literature published after 1970 are very few indeed. A survey of the literature cited indicates approximately 15 publications dated 1971 and even less for 1972, of which the latter refer almost exclusively to work of the authors. This apparent lack of up-to-date information is also reflected in the text, notably in the sections dealing with the optimisation of chromatographic performance, where there is hardly a mention of the current emphasis being placed on the use of column packings of less than 10-p diameter. Similarly, the description of apparatus for gradient elution, which is particularly detailed, fails to mention equipment introduced commercially over the last four years. Appendix 1 attempts to overcome this omission by listing the companies offering equipment for gradient liquid chromatography. On the other hand, considerable space is devoted to describing the construction of apparatus, particularly for use with paper and thinlayer techniques. The text contains considerable detail which could be of value to those wishing to understand or optimise gradient procedures. To derive the maximum benefit from the book, however, it would need to be studied rather than read. Letckworth
(Great Britaitl)
NORMAN
A. PARRIS