- Email: [email protected]
Granulomatous Mastitis – More data is needed
The Breast xxx (2016) 1
Contents lists available at ScienceDirect
The Breast journal homepage: www.elsevier.com/brst
Correspondence
Granulomatous Mastitis e More data are needed
Dear Editor in Chief, I read with great interest the article by Aghajanzadeh et al. on their experience in managing 206 cases of Granulomatous Mastitis (GM) in the North of Iran [1]. It is the largest series to date [2] and has provided me great insight into managing similar cases. The authors have advocated oral corticosteroid as the first line therapy for GM [1] and I concurred. However, in my clinical experience, many large GM breast lumps, typically those that are more than 7 cm, do not resolve with single course of oral prednisolone (8 weeks tapering course), and need further intervention. On the other hand, although the underlying lump does not resolve, ulcerated GM lesions response well with oral prednisolone with complete re-epithelialization in less than 4 weeks. It is of my great interest to know more and will be great if the authors can provide the bivariable analysis of the patients' characteristics and treatment outcomes, and multivariable analysis to look for the risk factors associated with treatment failure. These extended data will help clinicians to better understand the treatment efficacy and improve the patient's outcome. I sincerely look forward for the authors' reply.
Conflict of interest statement None. Funding source None. References [1] Aghajanzadeh M, Hassanzadeh R, Alizadeh Sefat S, Alavi A, Hemmati H, Esmaeili Delshad MS, et al. Granulomatous mastitis: presentations, diagnosis, treatment and outcome in 206 patients from the north of Iran. Breast 2015;24(4):456e60. [2] Altintoprak F, Kivilcim T, Ozkan OV. Aetiology of idiopathic granulomatous mastitis. World J Clin Cases 2014;2(12):852e8.
Feng Yih Chai* Department of Surgery, Hospital Keningau, Sabah, Malaysia * Department of Surgery, Hospital Keningau, KM5, Jalan Apin-Apin e Keningau, Peti Surat 11, 89009 Keningau, Sabah, Malaysia. Tel.: þ60 087 313 000. E-mail address: [email protected].
27 September 2015 Available online xxx
DOI of original article: http://dx.doi.org/10.1016/j.breast.2015.04.003. http://dx.doi.org/10.1016/j.breast.2015.12.006 0960-9776/© 2015 Elsevier Ltd. All rights reserved.
Please cite this article in press as: Chai FYGranulomatous Mastitis e More data are needed, The Breast (2016), http://dx.doi.org/10.1016/ j.breast.2015.12.006
Contents lists available at ScienceDirect
The Breast journal homepage: www.elsevier.com/brst
Correspondence
Granulomatous Mastitis e More data are needed
Dear Editor in Chief, I read with great interest the article by Aghajanzadeh et al. on their experience in managing 206 cases of Granulomatous Mastitis (GM) in the North of Iran [1]. It is the largest series to date [2] and has provided me great insight into managing similar cases. The authors have advocated oral corticosteroid as the first line therapy for GM [1] and I concurred. However, in my clinical experience, many large GM breast lumps, typically those that are more than 7 cm, do not resolve with single course of oral prednisolone (8 weeks tapering course), and need further intervention. On the other hand, although the underlying lump does not resolve, ulcerated GM lesions response well with oral prednisolone with complete re-epithelialization in less than 4 weeks. It is of my great interest to know more and will be great if the authors can provide the bivariable analysis of the patients' characteristics and treatment outcomes, and multivariable analysis to look for the risk factors associated with treatment failure. These extended data will help clinicians to better understand the treatment efficacy and improve the patient's outcome. I sincerely look forward for the authors' reply.
Conflict of interest statement None. Funding source None. References [1] Aghajanzadeh M, Hassanzadeh R, Alizadeh Sefat S, Alavi A, Hemmati H, Esmaeili Delshad MS, et al. Granulomatous mastitis: presentations, diagnosis, treatment and outcome in 206 patients from the north of Iran. Breast 2015;24(4):456e60. [2] Altintoprak F, Kivilcim T, Ozkan OV. Aetiology of idiopathic granulomatous mastitis. World J Clin Cases 2014;2(12):852e8.
Feng Yih Chai* Department of Surgery, Hospital Keningau, Sabah, Malaysia * Department of Surgery, Hospital Keningau, KM5, Jalan Apin-Apin e Keningau, Peti Surat 11, 89009 Keningau, Sabah, Malaysia. Tel.: þ60 087 313 000. E-mail address: [email protected].
27 September 2015 Available online xxx
DOI of original article: http://dx.doi.org/10.1016/j.breast.2015.04.003. http://dx.doi.org/10.1016/j.breast.2015.12.006 0960-9776/© 2015 Elsevier Ltd. All rights reserved.
Please cite this article in press as: Chai FYGranulomatous Mastitis e More data are needed, The Breast (2016), http://dx.doi.org/10.1016/ j.breast.2015.12.006