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Groningen TMJ total joint prosthesis development
204
P22-3 Temporomandibular joint & Pathology (cyst and others)
series, the tissues were embedded in Araldite. Thin sections were double-stained with uranyl acetate and lead citrate, and then examined with a JEOL 100-CX transmission electron microscope. Sympathetic nerve fibers were noted to be located mainly at the periphery. And, in these areas, these fibers are closely associated with blood vessels, including capillaries. Further findings regarding the distribution of 5-OHDA-positive sites at the subcellular level will be presented.
tion may be necessary for the treatment of cystic ameloblastoma. The type of surgery should not be determined and bone grafts must be avoided in case the diagnosis has not been established. Hundred IOLs in which the initial diagnosis was odontogenic cyst, were included into this prospective study. Cystic fluid had been aspirated from all lesions. The tentative diagnosis and the histopathologic diagnosis were compared. The results show that in some cases the necessity of frozen-section biopsy is eminent, particularly when reconstrution is planned using bonegrafts.
10. Groningen TMJ Total Joint Prosthesis Development
de Bont, L. G. M. 1, van Loon, J. P.~, Verkerke, B. 2
1Department of Oral and Maxillofacial Surgery, University Hospital Groningen, The Netherlands, 2Centre Jbr Biomedical Technology, University of Groningen, The Netherlands Non-successful results of temporomandibular joint (TMJ) surgery and resorptive joint pathology, necessitates the availability of a safe TMJ total joint prosthesis. For the reconstruction of oompletely mutilated TMJs, a well-functioning alloplastic joint replacement is not yet available. A proper design should be based on a comprehensive kinematic analysis of the prosthesis as well as of the contralateral natural TMJ, on a mechanical analysis of the device itself, and its fixation at the cranial side and mandibular ascending ramus side respectively, and on an analysis of the biocompatibility of the applied implant materials. An analysis of the variation in shape and size of the adjacent bony surfaces should avoid a custom-made design. Kinematic analysis resulted in an inferiorly located centre of rotation of the prosthetic condyle (US Patent Number 5.405.393). The design was further improved based on the result of dental implant studies. Proper fit at the cranial side could be achieved by using an adjustable design (International application for patent). The choice of implant material was based on results studies of orthopaedic total joints.. Wear tests are currently performed. The prototype of the Groningen TMJ total joint prosthesis represents the result of these analyses. A first series of testing of the devices in an animal model (sheep) has been successfully conducted.
11. Necessity of Frozen Section Biopsy in Treatment of Odontogenic Cysts
Usubutun, A. l, Sener, B. (7.2, Saysel, M. 2, Tasar, E 2
1Department of Pathology, Faculty of Medicine, 2Department of Oral Surgery, Faculty of Dentistry, Hacettepe University, Ankara, Turkey Treatment of intraosseous odontogenic lesions (IOL) depends on the type of the lesion. Differential diagnosis of IOL should be carried out with extreme care and caution. Simple enucleation can be carried out in cases of cysts, while resec-
12. Clinicupathologic Study of Odontogenic Tumors 110 Cases~During the Past 23 Years
Sohma, y.1, Ohashi, yl, Hoshina, no 1, Miyaura, y1, Nagashima, K, 1, Miyamoto, T,1, Tsurumaki, H. 1, Takagi, R. l, Suzuki, M. 2
12nd Department of 03/IS, and 2Clinical Laboratory, Niigata University Dental Hospital, Niigata, Japan The WHO histological typing of odontogenic tumors was revised in 1992. In this paper, we clinicopathologically reviewed 110 cases of odontogenic tumors histologically diagnosed according to the WHO classification in our clinic during the past 23 years (Dec. 1973-Nov. 1996). The results were as follows: The 110 cases consisted of 107 cases (97.3%) of benign odontogenic tumors and 3 cases (2.7%) of malignant tumors. Benign total Ameloblastoma Compound odontoma Complex odontoma Calcifying odontogenic cyst Odontogenic myxoma Odontogenic fibroma Ameloblastic fibro-odontoma Adenomatoid odontogenic tumor Benign cementoblastoma Malignant total Malignant ameloblastoma Primary intraosseous carcinoma Malignant changes in odontogenic cyst
107 (97.3%) 37 (33.7%) 36 (32.8%) 20 (18.2%) 4 (3.6%) 3 (2.7%) 3 (2.7%) 2 (1.8%) 1 (0.9%) 1 (0.9%) 3 (2.7%) 1 (0.9%) 1 (0.9%) 1 (0.9%)
All three odontogenic carcinomas developed extensively in the mandible, and were treated surgically. There has been no evidence of disease in one patient, one patient is now being treated, and the other patient died with a lung metastasis.
P22-3 Temporomandibular joint & Pathology (cyst and others)
series, the tissues were embedded in Araldite. Thin sections were double-stained with uranyl acetate and lead citrate, and then examined with a JEOL 100-CX transmission electron microscope. Sympathetic nerve fibers were noted to be located mainly at the periphery. And, in these areas, these fibers are closely associated with blood vessels, including capillaries. Further findings regarding the distribution of 5-OHDA-positive sites at the subcellular level will be presented.
tion may be necessary for the treatment of cystic ameloblastoma. The type of surgery should not be determined and bone grafts must be avoided in case the diagnosis has not been established. Hundred IOLs in which the initial diagnosis was odontogenic cyst, were included into this prospective study. Cystic fluid had been aspirated from all lesions. The tentative diagnosis and the histopathologic diagnosis were compared. The results show that in some cases the necessity of frozen-section biopsy is eminent, particularly when reconstrution is planned using bonegrafts.
10. Groningen TMJ Total Joint Prosthesis Development
de Bont, L. G. M. 1, van Loon, J. P.~, Verkerke, B. 2
1Department of Oral and Maxillofacial Surgery, University Hospital Groningen, The Netherlands, 2Centre Jbr Biomedical Technology, University of Groningen, The Netherlands Non-successful results of temporomandibular joint (TMJ) surgery and resorptive joint pathology, necessitates the availability of a safe TMJ total joint prosthesis. For the reconstruction of oompletely mutilated TMJs, a well-functioning alloplastic joint replacement is not yet available. A proper design should be based on a comprehensive kinematic analysis of the prosthesis as well as of the contralateral natural TMJ, on a mechanical analysis of the device itself, and its fixation at the cranial side and mandibular ascending ramus side respectively, and on an analysis of the biocompatibility of the applied implant materials. An analysis of the variation in shape and size of the adjacent bony surfaces should avoid a custom-made design. Kinematic analysis resulted in an inferiorly located centre of rotation of the prosthetic condyle (US Patent Number 5.405.393). The design was further improved based on the result of dental implant studies. Proper fit at the cranial side could be achieved by using an adjustable design (International application for patent). The choice of implant material was based on results studies of orthopaedic total joints.. Wear tests are currently performed. The prototype of the Groningen TMJ total joint prosthesis represents the result of these analyses. A first series of testing of the devices in an animal model (sheep) has been successfully conducted.
11. Necessity of Frozen Section Biopsy in Treatment of Odontogenic Cysts
Usubutun, A. l, Sener, B. (7.2, Saysel, M. 2, Tasar, E 2
1Department of Pathology, Faculty of Medicine, 2Department of Oral Surgery, Faculty of Dentistry, Hacettepe University, Ankara, Turkey Treatment of intraosseous odontogenic lesions (IOL) depends on the type of the lesion. Differential diagnosis of IOL should be carried out with extreme care and caution. Simple enucleation can be carried out in cases of cysts, while resec-
12. Clinicupathologic Study of Odontogenic Tumors 110 Cases~During the Past 23 Years
Sohma, y.1, Ohashi, yl, Hoshina, no 1, Miyaura, y1, Nagashima, K, 1, Miyamoto, T,1, Tsurumaki, H. 1, Takagi, R. l, Suzuki, M. 2
12nd Department of 03/IS, and 2Clinical Laboratory, Niigata University Dental Hospital, Niigata, Japan The WHO histological typing of odontogenic tumors was revised in 1992. In this paper, we clinicopathologically reviewed 110 cases of odontogenic tumors histologically diagnosed according to the WHO classification in our clinic during the past 23 years (Dec. 1973-Nov. 1996). The results were as follows: The 110 cases consisted of 107 cases (97.3%) of benign odontogenic tumors and 3 cases (2.7%) of malignant tumors. Benign total Ameloblastoma Compound odontoma Complex odontoma Calcifying odontogenic cyst Odontogenic myxoma Odontogenic fibroma Ameloblastic fibro-odontoma Adenomatoid odontogenic tumor Benign cementoblastoma Malignant total Malignant ameloblastoma Primary intraosseous carcinoma Malignant changes in odontogenic cyst
107 (97.3%) 37 (33.7%) 36 (32.8%) 20 (18.2%) 4 (3.6%) 3 (2.7%) 3 (2.7%) 2 (1.8%) 1 (0.9%) 1 (0.9%) 3 (2.7%) 1 (0.9%) 1 (0.9%) 1 (0.9%)
All three odontogenic carcinomas developed extensively in the mandible, and were treated surgically. There has been no evidence of disease in one patient, one patient is now being treated, and the other patient died with a lung metastasis.