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Growth in Japanese children receiving peritoneal dialysis
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Poster abstracts
Growth in Japanese children receiving peritoneal dialysis N. Wada 1, M. Honda 2 and the Study Group of the Pediatric Peritoneal Dialysis Conference in Japan ~Departmentof Pediatric Nephrology, Shizuka Children's Hospital, Shizuoka, and 2Departmentof Pediatric Nephrology, Tokyo Metropolitan Children's Hospital, Tokyo, Japan
The aim of this study was to examine spontaneous growth in Japanese children receiving peritoneal dialysis but no growth hormone. Growth data were collected retrospectively from 56 dialysis units on 748 patients in whom the onset of peritoneal dialysis was before the age of 15 years. Heights were recorded at the start of peritoneal dialysis and every year thereafter for 5 years, and height SDS, growth rate and growth rate SDS were assessed. The mean height at the start of peritoneal dialysis was -2.23 ± 1.76 SDS, and this regressed in a linear fashion every year thereafter (-0.24 SD/year). There was no significant difference between boys and girls. In patients followed for 5 years, the mean height SDS and growth rate of the patients who started peritoneal dialysis before puberty were lower than those of the
patients who began peritoneal dialysis after puberty. The mean height SDS of the patients with congenital renal disorders was significantly lower than that of the patients with acquired renal disorders at the start of peritoneal dialysis (-2.48 + 0.41 vs 1.48 _+ 0.26). However, after 5 years of peritoneal dialysis, the mean height SDS of the two groups of patients did not differ (-3.36 + 0.46 vs -3.32 ± 1.46), because the growth rate of patients with congenital disease was better than that of patients with acquired disease. In conclusion, long-term growth was severely retarded in children receiving peritoneal dialysis in Japan. In particular, patients who are young at the start of peritoneal dialysis are more affected by growth impairment than older patients.
Poster abstracts
Growth in Japanese children receiving peritoneal dialysis N. Wada 1, M. Honda 2 and the Study Group of the Pediatric Peritoneal Dialysis Conference in Japan ~Departmentof Pediatric Nephrology, Shizuka Children's Hospital, Shizuoka, and 2Departmentof Pediatric Nephrology, Tokyo Metropolitan Children's Hospital, Tokyo, Japan
The aim of this study was to examine spontaneous growth in Japanese children receiving peritoneal dialysis but no growth hormone. Growth data were collected retrospectively from 56 dialysis units on 748 patients in whom the onset of peritoneal dialysis was before the age of 15 years. Heights were recorded at the start of peritoneal dialysis and every year thereafter for 5 years, and height SDS, growth rate and growth rate SDS were assessed. The mean height at the start of peritoneal dialysis was -2.23 ± 1.76 SDS, and this regressed in a linear fashion every year thereafter (-0.24 SD/year). There was no significant difference between boys and girls. In patients followed for 5 years, the mean height SDS and growth rate of the patients who started peritoneal dialysis before puberty were lower than those of the
patients who began peritoneal dialysis after puberty. The mean height SDS of the patients with congenital renal disorders was significantly lower than that of the patients with acquired renal disorders at the start of peritoneal dialysis (-2.48 + 0.41 vs 1.48 _+ 0.26). However, after 5 years of peritoneal dialysis, the mean height SDS of the two groups of patients did not differ (-3.36 + 0.46 vs -3.32 ± 1.46), because the growth rate of patients with congenital disease was better than that of patients with acquired disease. In conclusion, long-term growth was severely retarded in children receiving peritoneal dialysis in Japan. In particular, patients who are young at the start of peritoneal dialysis are more affected by growth impairment than older patients.