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GW27-e0813 Prevalence and Determinant Factors of Sarcopenia in Patients with Cardiovascular Risk Factors
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, VOL. 68, NO. 16, SUPPL S, 2016
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never-smokers (29,660 men; age 34.66.6 years) between 2011 and 2013 who had urinary cotinine measurements were included. Never-smoker was defined from self-reported questionnaire and cotinine-verified SHS was defined as urinary cotinine level above 50 ng/mL.
METHODS In total, 14,618 adult participants (7,799 males, 6,819 females) were recruited from the Cardiovascular Risk Survey conducted during 2007 and 2010. Blood pressure, body mass index and standard lipid profile and fasting glucose level from plasma were measured.
RESULTS The prevalence of cotinine-verified SHS was 2.0% and 1.6% in men and women, respectively; the prevalence of MetS was 11.1% in men and 3.6% in women. In both sex, the prevalence of MetS in cotinine-verified SHS group was significantly higher than in cotinineverified non-exposure group (16.9% vs. 11.0%, p<0.001 for men: 5.1% vs. 3.5%, p¼0.025 for women). Cotinine-verified SHS group in both sex had significantly increased frequency and amount of alcoholic drinking compared with non-exposure group (more than 3 times/ week: 13.6% vs. 10.0% for men and 15.6% vs. 5.0% for women, daily amount of alcohol drinking[more than 30g/day in men and more than 20 g/day in women]: 15.6% vs. 11.2% for men, 16.7% vs. 5.4% for women). Multivariate logistic regression model adjusted for age, body mass index, daily amount of alcohol drinking, exercise, total cholesterol, creatinine, uric acid, and high-sensitivity C reactive protein showed that cotinine-verified SHS significantly increased the odds ratio (OR) for MetS compared with cotinine-verified non-exposed group in women (OR[95% CI], 1.77[1.18, 2.68], p¼0.006), but not in men (1.26[0.94, 1.69], p¼0.118). In the results after adjusting for the five components of MetS, cotinine-verified SHS showed a trend toward MetS in women (1.64[0.94, 2.87], p¼0.08) but was not associated with MetS in men (1.14[0.78, 1.65], p¼0.508).
RESULTS The overall age-standardized prevalence of MS was 35.05% in the Han, 31.9% in the Uygur and 30.4% in the Kazakh populations based on definitions of revised NCEP ATPIII criteria, respectively. When stratified by gender, MS prevalence was 41.9% in men and, 39.5% in women (P<0.001) based on definitions of revised NCEP ATPIII criteria, respectively. The prevalence of MS also varied significantly with age and it was highest in those over 75 yrs old (51.6%) and lowest aged 35-44 yrs old (21.8% P<0.001) based on definitions of revised NCEP ATPIII criteria, respectively. Multivariate logistic regression analysis showed that over 65 yrs old (OR¼3.271, 95%CI: 2.681-3.990), overweight (OR¼3.368, 95%CI: 2.866-3.959) or obesity (OR¼5.926, 95%CI: 5.007-7.014) anddrinking (OR¼1.445, 95%CI: 1.1091.884) were significantly associated with a higher prevalence of MS. Identified risk factors for MS differed among ethnicity groups with smoking in the Han; male gender in the Uygur populations.
CONCLUSIONS This study shows that cotinine-verified SHS group had higher prevalence of MetS in both sex but after adjusting for multiple covariates cotinine-verified SHS is associated with MetS only in women. GW27-e0553 Epidemiological features of lipid metabolism in the male population of working age in baku and internally displaced persons in sumgait city Mursalov Muqabil,1,2,3 Zeynalov AF,2 Gasimova FN3 1 Azerbaijan State Advanced Training Institute for Doctors named after A. Aliyev; 2Department of Family Medicine; 3Department of Therapy OBJECTIVES To conduct a comparative analysis of the basic parameters of lipid metabolism of two population-epidemiological studies, among the male population of Baku and internally displaced persons (IDP) live in Sumgait city. METHODS In order to obtain valid data, two representative samples of the 865 male population of the city of Baku and internally displaced persons live in Sumgait city. As in one, and in another study used strictly standardized survey methods and evaluation criteria. Statistical analysis was carried out in accordance with modern requirements. RESULTS The results showed that the average concentration of total cholesterol (TC) in the blood plasma in the male population of Baku was 4,59 0,09 mmol/l, the rate was 5,4 0, 1 mmol among the IDP, which was statistically significantly higher (p <0,05). The ratio of the average concentration of TG in plasma of a comparable population of individuals amounted to 2,18 0,08 mmol/l and 1,8 0,5 mmol/l (p <0,05), and the average concentration of HDL cholesterol was 0.86 0,07 and 1,19 0,03 (p <0,05). Consequently, the atherogenic lipid spectrum was higher among the Baku population of individuals. Hypercholesterolemia registration rate in both populations were individuals below: Baku - 12.37%, in Sumgait: 4,2% and 53,5 5,5% (p <0,05), hyper-TG - 45.1 6, 6% and 52,5 2,1% (p> 0,05) and hypoHDL-52,4 4,4% and 54,1 4,8% (p> 0,05). CONCLUSIONS Despite the fact that higher levels of lipid profile among the male population were recorded in Baku, the immediate correction of the current epidemiological situation it is necessary to representatives of both populations. GW27-e0601 Prevalence of metabolic syndrome and its influencing factors among Different Ethnicity Groups in Xinjiang, China: the Cardiovascular Risk Survey during 2007 - 2010 Dilare Adi, Fen Liu, Xiang Xie, Yun Wu, yitong ma, yining yang Department of Cardiology, the First Affiliated Hospital of Xinjiang Medical University, Urumqi, PRC OBJECTIVES Little is known about Prevalence of metabolic syndrome and its influencing factors among different ethnicity groups. We aimed to investigate the prevalence and risk factors for MS among the major ethnicity population i.e. Han, Uygur and Kazakh in Xinjiang, northwestern part of China.
CONCLUSIONS MS prevalence in the Han population is higher than that in the Uygur and Kazak populations in Xinjiang, northwestern part of China. Male gender, older age, overweight or obesity and drinking appear to be relevant risk factors of MS. These findings emphasize the urgent need to develop national strategies for the prevention, detection, and treatment of MS and sets of risk factors for MS among different Ethnicity Groups. GW27-e0813 Prevalence and Determinant Factors of Sarcopenia in Patients with Cardiovascular Risk Factors Peipei Han,1,2 Qi Guo1,2 1 Department of Rehabilitation and Sports Medicine, Tianjin Medical University, Tianjin, China; 2Department of Rehabilitation Medicine, Cardiovascular Clinical College of Tianjin Medical University, TEDA International Cardiovascular Hospital, Tian OBJECTIVES The aim of the present study was to examine the prevalence of sarcopenia in Chinese suburb-dwelling patients with cardiovascular risk factors and compared sarcopenia and sarcopenia components between subjects with and without cardiovascular risk factors. METHODS This study was conducted on 766 Chinese suburb-dwelling subjects (488 patients with cardiovascular risk factors) who were examined using bioelectrical impedance analysis. Prevalence of sarcopenia was using Asian Working Group for Sarcopenia (AWGS) criteria. Furthermore, multiple logistic regression analysis was used to examine the effects of cardiovascular risk factors on sarcopenia and sarcopenia components. RESULTS The total prevalence of sarcopenia was 11.3% in patients with cardiovascular risk factors; prevalence was 7.4% and 35.8% in patients with cardiovascular risk factors aged 60-74 and 75, respectively. After adjustments for confounders (age, gender, BMI, smoking, drinking and physical activity), cardiovascular risk factors was independently associated with sarcopenia (OR¼2.75, 95% CI¼1.50-5.05). Among the individual components of sarcopenia, low gait speed (OR¼2.70, 95% CI¼1.10-6.67), but not low grip strength (OR¼1.02, 95% CI¼0.99-1. 05) and low muscle mass (OR¼1.01, 95% CI¼0.98-1.03) was associated with cardiovascular risk factors after multivariable adjustments. CONCLUSIONS The AWGS criterion is useful for defining sarcopenia and our data suggest that the prevalence of sarcopenia in Chinese suburbdwelling patients with cardiovascular risk factors is high. Moreover, we find that cardiovascular risk factors were independently associated with sarcopenia. These characteristics may contribute to low gait speed in suburb-dwelling populations with cardiovascular risk factors. GW27-e0890 Effects of Temperature and Air Pollution on Outpatient and Emergency Department Visits for Cardiovascular Diseases in Shanghai, China Xu Anyang,1 Zhe Mu,2 Lijuan Zhang,1 Jue Li1 Department of Public Health and Preventive Medicine, Medical School, Tongji University, Shanghai, China; 2Shanghai Key Laboratory of Meteorology and Health, Shanghai Meteorological Service, Shanghai, China 1
OBJECTIVES We explore the acute effects of temperature and air pollution on the number of daily outpatient and emergency department visits of cardiovascular diseases in shanghai. METHODS The air pollution data, temperature data and outpatient and emergency department visits of cardiovascular diseases data were
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never-smokers (29,660 men; age 34.66.6 years) between 2011 and 2013 who had urinary cotinine measurements were included. Never-smoker was defined from self-reported questionnaire and cotinine-verified SHS was defined as urinary cotinine level above 50 ng/mL.
METHODS In total, 14,618 adult participants (7,799 males, 6,819 females) were recruited from the Cardiovascular Risk Survey conducted during 2007 and 2010. Blood pressure, body mass index and standard lipid profile and fasting glucose level from plasma were measured.
RESULTS The prevalence of cotinine-verified SHS was 2.0% and 1.6% in men and women, respectively; the prevalence of MetS was 11.1% in men and 3.6% in women. In both sex, the prevalence of MetS in cotinine-verified SHS group was significantly higher than in cotinineverified non-exposure group (16.9% vs. 11.0%, p<0.001 for men: 5.1% vs. 3.5%, p¼0.025 for women). Cotinine-verified SHS group in both sex had significantly increased frequency and amount of alcoholic drinking compared with non-exposure group (more than 3 times/ week: 13.6% vs. 10.0% for men and 15.6% vs. 5.0% for women, daily amount of alcohol drinking[more than 30g/day in men and more than 20 g/day in women]: 15.6% vs. 11.2% for men, 16.7% vs. 5.4% for women). Multivariate logistic regression model adjusted for age, body mass index, daily amount of alcohol drinking, exercise, total cholesterol, creatinine, uric acid, and high-sensitivity C reactive protein showed that cotinine-verified SHS significantly increased the odds ratio (OR) for MetS compared with cotinine-verified non-exposed group in women (OR[95% CI], 1.77[1.18, 2.68], p¼0.006), but not in men (1.26[0.94, 1.69], p¼0.118). In the results after adjusting for the five components of MetS, cotinine-verified SHS showed a trend toward MetS in women (1.64[0.94, 2.87], p¼0.08) but was not associated with MetS in men (1.14[0.78, 1.65], p¼0.508).
RESULTS The overall age-standardized prevalence of MS was 35.05% in the Han, 31.9% in the Uygur and 30.4% in the Kazakh populations based on definitions of revised NCEP ATPIII criteria, respectively. When stratified by gender, MS prevalence was 41.9% in men and, 39.5% in women (P<0.001) based on definitions of revised NCEP ATPIII criteria, respectively. The prevalence of MS also varied significantly with age and it was highest in those over 75 yrs old (51.6%) and lowest aged 35-44 yrs old (21.8% P<0.001) based on definitions of revised NCEP ATPIII criteria, respectively. Multivariate logistic regression analysis showed that over 65 yrs old (OR¼3.271, 95%CI: 2.681-3.990), overweight (OR¼3.368, 95%CI: 2.866-3.959) or obesity (OR¼5.926, 95%CI: 5.007-7.014) anddrinking (OR¼1.445, 95%CI: 1.1091.884) were significantly associated with a higher prevalence of MS. Identified risk factors for MS differed among ethnicity groups with smoking in the Han; male gender in the Uygur populations.
CONCLUSIONS This study shows that cotinine-verified SHS group had higher prevalence of MetS in both sex but after adjusting for multiple covariates cotinine-verified SHS is associated with MetS only in women. GW27-e0553 Epidemiological features of lipid metabolism in the male population of working age in baku and internally displaced persons in sumgait city Mursalov Muqabil,1,2,3 Zeynalov AF,2 Gasimova FN3 1 Azerbaijan State Advanced Training Institute for Doctors named after A. Aliyev; 2Department of Family Medicine; 3Department of Therapy OBJECTIVES To conduct a comparative analysis of the basic parameters of lipid metabolism of two population-epidemiological studies, among the male population of Baku and internally displaced persons (IDP) live in Sumgait city. METHODS In order to obtain valid data, two representative samples of the 865 male population of the city of Baku and internally displaced persons live in Sumgait city. As in one, and in another study used strictly standardized survey methods and evaluation criteria. Statistical analysis was carried out in accordance with modern requirements. RESULTS The results showed that the average concentration of total cholesterol (TC) in the blood plasma in the male population of Baku was 4,59 0,09 mmol/l, the rate was 5,4 0, 1 mmol among the IDP, which was statistically significantly higher (p <0,05). The ratio of the average concentration of TG in plasma of a comparable population of individuals amounted to 2,18 0,08 mmol/l and 1,8 0,5 mmol/l (p <0,05), and the average concentration of HDL cholesterol was 0.86 0,07 and 1,19 0,03 (p <0,05). Consequently, the atherogenic lipid spectrum was higher among the Baku population of individuals. Hypercholesterolemia registration rate in both populations were individuals below: Baku - 12.37%, in Sumgait: 4,2% and 53,5 5,5% (p <0,05), hyper-TG - 45.1 6, 6% and 52,5 2,1% (p> 0,05) and hypoHDL-52,4 4,4% and 54,1 4,8% (p> 0,05). CONCLUSIONS Despite the fact that higher levels of lipid profile among the male population were recorded in Baku, the immediate correction of the current epidemiological situation it is necessary to representatives of both populations. GW27-e0601 Prevalence of metabolic syndrome and its influencing factors among Different Ethnicity Groups in Xinjiang, China: the Cardiovascular Risk Survey during 2007 - 2010 Dilare Adi, Fen Liu, Xiang Xie, Yun Wu, yitong ma, yining yang Department of Cardiology, the First Affiliated Hospital of Xinjiang Medical University, Urumqi, PRC OBJECTIVES Little is known about Prevalence of metabolic syndrome and its influencing factors among different ethnicity groups. We aimed to investigate the prevalence and risk factors for MS among the major ethnicity population i.e. Han, Uygur and Kazakh in Xinjiang, northwestern part of China.
CONCLUSIONS MS prevalence in the Han population is higher than that in the Uygur and Kazak populations in Xinjiang, northwestern part of China. Male gender, older age, overweight or obesity and drinking appear to be relevant risk factors of MS. These findings emphasize the urgent need to develop national strategies for the prevention, detection, and treatment of MS and sets of risk factors for MS among different Ethnicity Groups. GW27-e0813 Prevalence and Determinant Factors of Sarcopenia in Patients with Cardiovascular Risk Factors Peipei Han,1,2 Qi Guo1,2 1 Department of Rehabilitation and Sports Medicine, Tianjin Medical University, Tianjin, China; 2Department of Rehabilitation Medicine, Cardiovascular Clinical College of Tianjin Medical University, TEDA International Cardiovascular Hospital, Tian OBJECTIVES The aim of the present study was to examine the prevalence of sarcopenia in Chinese suburb-dwelling patients with cardiovascular risk factors and compared sarcopenia and sarcopenia components between subjects with and without cardiovascular risk factors. METHODS This study was conducted on 766 Chinese suburb-dwelling subjects (488 patients with cardiovascular risk factors) who were examined using bioelectrical impedance analysis. Prevalence of sarcopenia was using Asian Working Group for Sarcopenia (AWGS) criteria. Furthermore, multiple logistic regression analysis was used to examine the effects of cardiovascular risk factors on sarcopenia and sarcopenia components. RESULTS The total prevalence of sarcopenia was 11.3% in patients with cardiovascular risk factors; prevalence was 7.4% and 35.8% in patients with cardiovascular risk factors aged 60-74 and 75, respectively. After adjustments for confounders (age, gender, BMI, smoking, drinking and physical activity), cardiovascular risk factors was independently associated with sarcopenia (OR¼2.75, 95% CI¼1.50-5.05). Among the individual components of sarcopenia, low gait speed (OR¼2.70, 95% CI¼1.10-6.67), but not low grip strength (OR¼1.02, 95% CI¼0.99-1. 05) and low muscle mass (OR¼1.01, 95% CI¼0.98-1.03) was associated with cardiovascular risk factors after multivariable adjustments. CONCLUSIONS The AWGS criterion is useful for defining sarcopenia and our data suggest that the prevalence of sarcopenia in Chinese suburbdwelling patients with cardiovascular risk factors is high. Moreover, we find that cardiovascular risk factors were independently associated with sarcopenia. These characteristics may contribute to low gait speed in suburb-dwelling populations with cardiovascular risk factors. GW27-e0890 Effects of Temperature and Air Pollution on Outpatient and Emergency Department Visits for Cardiovascular Diseases in Shanghai, China Xu Anyang,1 Zhe Mu,2 Lijuan Zhang,1 Jue Li1 Department of Public Health and Preventive Medicine, Medical School, Tongji University, Shanghai, China; 2Shanghai Key Laboratory of Meteorology and Health, Shanghai Meteorological Service, Shanghai, China 1
OBJECTIVES We explore the acute effects of temperature and air pollution on the number of daily outpatient and emergency department visits of cardiovascular diseases in shanghai. METHODS The air pollution data, temperature data and outpatient and emergency department visits of cardiovascular diseases data were