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H 031 THE PREVALENCE OF METABOLIC SYNDROME IN PATIENTS SUFFERING FROM HYPERTENSIVE CRISES
H 030
RISK FACTORS PROFILE OF MEN AND WOMEN WITH ACUTE MYOCARDIAL INFARCTION IN A SOUTH AMERICAN CORONARY UNIT: COMPARISON IN 1995 AND 2005
for EHC and 56.9±15.5 for UHC (p=0.0007) with a prevalence of men in EHC (61.4% versus 45.1%; p=0.01). The prevalence of MS was significantly higher in EHC (71.5% versus 59.2%; p=0.04) as was glycemia (151.7±72 versus 124.17±60; p=0.002). The AMI-EHC subgroup presented a prevalence of 83.3% of MS and lower mean HDL-cholesterol (36.83±11.3 versus 42.6±14.2 in the UHC Group; p=0.02). Other analyzed parameters did not present with significant differences. In conclusion, a high prevalence of MS was seen in individuals with HC, specifically for EHC, with age, men, high blood sugar and low HDL cholesterol levels being associated with this condition.
Rita Simone Lopes, Iran Gonçalves Junior, Jose Marconi Almeida de Sousa, Antonio Carlos de Camargo Carvalho Hospital São Paulo São Paulo SP BRASIL e Universidade Federal de São Paulo São Paulo SP BRASIL Background: Coronary heart disease ( CAD) is the leading cause of death in Brazil. Although this condition is still considered prevalent in men, it has changed during the last decades. In the 70’s there were 10 men for each woman and now the proportion is 2.16 for one. Hypertension (Hy), diabetes (DM) and smoking (SM) are described as risk factors of high impact for coronary heart disease that are modifiable. Objective: To compare the risk factors profile of men and women with acute myocardial infarction (MI) in ten years, hypertension, diabetes and smoking in both groups. Methods: Transversal, retrospective study of 211 patients interned in a coronary unit of a Brazilian school hospital from 1995 to 2005 was performed. All patients interned with acute MI (with Q or non-Q) were included and their records were examined in order to detect the three chosen variables: Hy, DM and SM. Results: In 1995 the N was 105 patients, that were 67 men (63,81%) and 38 women (36.19%) and in 2005, N=106, with 72 men (67.92%) and 34 women (32.07%). The analysis of the studied variables showed no significant differences among men and women regarding the incidence of MI, Hy, DM and SM. Sex/HY F M T
1995 N 27 30 57
2005 % 47,4 37,5 41,6
N 30 50 80
H 032
José F V Martin, Renan O V Melo, Lizzie Milléo, Letícia G Andrade, Juan C Y Toledo, Afonso A C Loureiro, Marcela A S Pinhel, Rafael Y Matsumoto, Emerson C Marino, Doroteia R S Souza Faculdade de Medicina de São José do Rio Preto-FAMERP São José do Rio Preto SP BRAZIL. Systemic arterial hypertension (SAH) affects 60 to 70% of the elderly population. The elderly are more prone to present cognitive deficit (CD) resulting from senility and from the association of illnesses, among them SAH and its complications (strokes). Our objective was to study the relationship between SAH and cognitive function in mentally fit hypertensive individuals and to investigate if risk factors (pulse pressure, smoking, alcohol consume, body mass index – BMI, diabetes – DM, dyslipidemia and prior stroke (CVA) are associated to the development of CD. Two hundred and twenty-three patients ³ 40 years old with SAH and without dementia syndrome were studied, paired by sex and age, who, after application of the Mini Mental test to assess cognitive function, were split into groups with CD and without CD. A mini mental test score £ 23 points suggested CD. SAH was defined when the average of 03 measures of arterial pressure (AP) was ³140/90 mm Hg or if the individual describe previous treatment of hypertension. DM was considered when fast glycemia ³ 126 mg/dl or £ 126 mg/dl using hypoglicemic agents. The non-paired t-test and Fisher test were used. P < 0.05 was significant. The group with CD included 67 patients (42 women) and without CD 156 (83 women) with an average age without statistical difference (62.7± 12.3 x 61.7 ± 10 years, respectively). The group with CD presented the lowest score (p<0.0001), lower DBP (p<0.005), and greater frequency of prior CVA (p<0.05 – relative risk 2.16 CI: 1.25 –3.74) than the group without CD. All other factors did not present statistical difference. To conclude, CVA is associated to cognitive deficit, doubling the risk of the elderly hypertense developing cognitive dysfunction. Lower diastolic pressure is also associated to a higher CD, which shows that the control of SAH is the best way to prevent CVA and the reduced cognitive function in the hypertensive elderly.
Total % 52,6 62,5 58,4
N 57 80 137
% 41,6 58,4 100,0
Pearson’s Test– x2 = 1.33/ p= 0.2481 – Yates’s Test – x2= 0.96/p= 0.3275 Conclusion: The fact that HY as high impact risk factors are present in men and women with no significant differences demonstrates that both groups with MI must receive the same treatment regarding CAD. H 031
STROKE AND DIASTOLIC BLOOD PRESSURE ASSOCIATED TO COGNITIVE DYSFUNCTION IN ELDERLY HYPERTENSIVE INDIVIDUALS
THE PREVALENCE OF METABOLIC SYNDROME IN PATIENTS SUFFERING FROM HYPERTENSIVE CRISES
José Fernando Vilela Martin, André Néder Ramires Abdo, Cristina Hiromi Kuniyoshi, José Paulo Cipullo, Juan Carlos Yugar Toledo, Letícia G Andrade, Afonso A Carvalho Loureiro, Doroteia Rossi Silva Souza, Marcela Augusta Souza Pinhel
H 033
Faculdade de Medicina de São Jose do Rio Preto-FAMERP, São Jose do Rio Preto SP BRASIL Metabolic syndrome (MS), an association of metabolic alterations, represents a significant cardiovascular risk factor. Hypertensive crises are a complication of high blood pressure that courses with a symptomatic acute elevation of diastolic arterial pressure (DAP = 120 mmHg), classified as emergency (EHC) when accompanied by target-organ lesions or urgency (UHC) when not. The objectives of this study were to analyze the prevalence of MS in patients with EHC and UHC, evaluating metabolic parameters. A total of 239 patients,130 UHC and 109 EHC( 30 suffering from acute myocardial infarctions “AMI” – and 79 from strokes “AVE”) were evaluated. Age, gender, ethnical background (white and non-white), waist size, fasting blood sugar, total cholesterol, HDL cholesterol, triglycerides, creatinine, and uric acid were assessed. MS implicated three or more criteria (fasting blood glucose = 100mg/dL; systemic arterial hypertension; triglycerides = 150mg/dL; waist = 102 cm for men and = 88 cm for women and HDL cholesterol <40 mg/dL for men and <50 mg/dL for women). The t-test was utilized to compare quantitative variables and the Fisher exact test to compare prevalences of MS with statistical significance set for a p-value <0.05. The mean age was 63±13 years
ASSOCIATED RISK FACTORS AND CARDIOVASCULAR RISK STRATIFICATION IN THE POPULATION ATTENDED IN THE COMMUNITY GATHERING TO PREVENT KIDNEY DISEASE, IN SÃO LUÍS-MA, BRAZIL, 2006
Camila M Polary, Allison N Santos, George D L Pinheiro, João R Jr, Pâmela S S Chaves, Maíra C Lopes, Tália B Teixeira UFMA São Luís MA BRAZIL. Introduction: Early cardiovascular risk (CV) stratification is important to define possible therapeutic intervention. Our aim is to assess the prevalence of the risk factors implied in a prior prognosis for the CV disease and to relate them to the blood pressure levels measured in persons attended at a community gathering for prevention of kidney disease. Method: Cross-section study of 173 people attended in a community gathering in the city of São Luís in 2006. A questionnaire was applied containing demographic data, clinical history, physical examination and laboratory assessment results. CV risk factors were evaluated: age, systemic arterial hypertension (SAH), Diabetes Mellitus (DM), smoking, dyslipidemy, CV disease family history (FH) and nephropathy. The analysis and processing of the data were performed in the software EpiInfo.
13
RISK FACTORS PROFILE OF MEN AND WOMEN WITH ACUTE MYOCARDIAL INFARCTION IN A SOUTH AMERICAN CORONARY UNIT: COMPARISON IN 1995 AND 2005
for EHC and 56.9±15.5 for UHC (p=0.0007) with a prevalence of men in EHC (61.4% versus 45.1%; p=0.01). The prevalence of MS was significantly higher in EHC (71.5% versus 59.2%; p=0.04) as was glycemia (151.7±72 versus 124.17±60; p=0.002). The AMI-EHC subgroup presented a prevalence of 83.3% of MS and lower mean HDL-cholesterol (36.83±11.3 versus 42.6±14.2 in the UHC Group; p=0.02). Other analyzed parameters did not present with significant differences. In conclusion, a high prevalence of MS was seen in individuals with HC, specifically for EHC, with age, men, high blood sugar and low HDL cholesterol levels being associated with this condition.
Rita Simone Lopes, Iran Gonçalves Junior, Jose Marconi Almeida de Sousa, Antonio Carlos de Camargo Carvalho Hospital São Paulo São Paulo SP BRASIL e Universidade Federal de São Paulo São Paulo SP BRASIL Background: Coronary heart disease ( CAD) is the leading cause of death in Brazil. Although this condition is still considered prevalent in men, it has changed during the last decades. In the 70’s there were 10 men for each woman and now the proportion is 2.16 for one. Hypertension (Hy), diabetes (DM) and smoking (SM) are described as risk factors of high impact for coronary heart disease that are modifiable. Objective: To compare the risk factors profile of men and women with acute myocardial infarction (MI) in ten years, hypertension, diabetes and smoking in both groups. Methods: Transversal, retrospective study of 211 patients interned in a coronary unit of a Brazilian school hospital from 1995 to 2005 was performed. All patients interned with acute MI (with Q or non-Q) were included and their records were examined in order to detect the three chosen variables: Hy, DM and SM. Results: In 1995 the N was 105 patients, that were 67 men (63,81%) and 38 women (36.19%) and in 2005, N=106, with 72 men (67.92%) and 34 women (32.07%). The analysis of the studied variables showed no significant differences among men and women regarding the incidence of MI, Hy, DM and SM. Sex/HY F M T
1995 N 27 30 57
2005 % 47,4 37,5 41,6
N 30 50 80
H 032
José F V Martin, Renan O V Melo, Lizzie Milléo, Letícia G Andrade, Juan C Y Toledo, Afonso A C Loureiro, Marcela A S Pinhel, Rafael Y Matsumoto, Emerson C Marino, Doroteia R S Souza Faculdade de Medicina de São José do Rio Preto-FAMERP São José do Rio Preto SP BRAZIL. Systemic arterial hypertension (SAH) affects 60 to 70% of the elderly population. The elderly are more prone to present cognitive deficit (CD) resulting from senility and from the association of illnesses, among them SAH and its complications (strokes). Our objective was to study the relationship between SAH and cognitive function in mentally fit hypertensive individuals and to investigate if risk factors (pulse pressure, smoking, alcohol consume, body mass index – BMI, diabetes – DM, dyslipidemia and prior stroke (CVA) are associated to the development of CD. Two hundred and twenty-three patients ³ 40 years old with SAH and without dementia syndrome were studied, paired by sex and age, who, after application of the Mini Mental test to assess cognitive function, were split into groups with CD and without CD. A mini mental test score £ 23 points suggested CD. SAH was defined when the average of 03 measures of arterial pressure (AP) was ³140/90 mm Hg or if the individual describe previous treatment of hypertension. DM was considered when fast glycemia ³ 126 mg/dl or £ 126 mg/dl using hypoglicemic agents. The non-paired t-test and Fisher test were used. P < 0.05 was significant. The group with CD included 67 patients (42 women) and without CD 156 (83 women) with an average age without statistical difference (62.7± 12.3 x 61.7 ± 10 years, respectively). The group with CD presented the lowest score (p<0.0001), lower DBP (p<0.005), and greater frequency of prior CVA (p<0.05 – relative risk 2.16 CI: 1.25 –3.74) than the group without CD. All other factors did not present statistical difference. To conclude, CVA is associated to cognitive deficit, doubling the risk of the elderly hypertense developing cognitive dysfunction. Lower diastolic pressure is also associated to a higher CD, which shows that the control of SAH is the best way to prevent CVA and the reduced cognitive function in the hypertensive elderly.
Total % 52,6 62,5 58,4
N 57 80 137
% 41,6 58,4 100,0
Pearson’s Test– x2 = 1.33/ p= 0.2481 – Yates’s Test – x2= 0.96/p= 0.3275 Conclusion: The fact that HY as high impact risk factors are present in men and women with no significant differences demonstrates that both groups with MI must receive the same treatment regarding CAD. H 031
STROKE AND DIASTOLIC BLOOD PRESSURE ASSOCIATED TO COGNITIVE DYSFUNCTION IN ELDERLY HYPERTENSIVE INDIVIDUALS
THE PREVALENCE OF METABOLIC SYNDROME IN PATIENTS SUFFERING FROM HYPERTENSIVE CRISES
José Fernando Vilela Martin, André Néder Ramires Abdo, Cristina Hiromi Kuniyoshi, José Paulo Cipullo, Juan Carlos Yugar Toledo, Letícia G Andrade, Afonso A Carvalho Loureiro, Doroteia Rossi Silva Souza, Marcela Augusta Souza Pinhel
H 033
Faculdade de Medicina de São Jose do Rio Preto-FAMERP, São Jose do Rio Preto SP BRASIL Metabolic syndrome (MS), an association of metabolic alterations, represents a significant cardiovascular risk factor. Hypertensive crises are a complication of high blood pressure that courses with a symptomatic acute elevation of diastolic arterial pressure (DAP = 120 mmHg), classified as emergency (EHC) when accompanied by target-organ lesions or urgency (UHC) when not. The objectives of this study were to analyze the prevalence of MS in patients with EHC and UHC, evaluating metabolic parameters. A total of 239 patients,130 UHC and 109 EHC( 30 suffering from acute myocardial infarctions “AMI” – and 79 from strokes “AVE”) were evaluated. Age, gender, ethnical background (white and non-white), waist size, fasting blood sugar, total cholesterol, HDL cholesterol, triglycerides, creatinine, and uric acid were assessed. MS implicated three or more criteria (fasting blood glucose = 100mg/dL; systemic arterial hypertension; triglycerides = 150mg/dL; waist = 102 cm for men and = 88 cm for women and HDL cholesterol <40 mg/dL for men and <50 mg/dL for women). The t-test was utilized to compare quantitative variables and the Fisher exact test to compare prevalences of MS with statistical significance set for a p-value <0.05. The mean age was 63±13 years
ASSOCIATED RISK FACTORS AND CARDIOVASCULAR RISK STRATIFICATION IN THE POPULATION ATTENDED IN THE COMMUNITY GATHERING TO PREVENT KIDNEY DISEASE, IN SÃO LUÍS-MA, BRAZIL, 2006
Camila M Polary, Allison N Santos, George D L Pinheiro, João R Jr, Pâmela S S Chaves, Maíra C Lopes, Tália B Teixeira UFMA São Luís MA BRAZIL. Introduction: Early cardiovascular risk (CV) stratification is important to define possible therapeutic intervention. Our aim is to assess the prevalence of the risk factors implied in a prior prognosis for the CV disease and to relate them to the blood pressure levels measured in persons attended at a community gathering for prevention of kidney disease. Method: Cross-section study of 173 people attended in a community gathering in the city of São Luís in 2006. A questionnaire was applied containing demographic data, clinical history, physical examination and laboratory assessment results. CV risk factors were evaluated: age, systemic arterial hypertension (SAH), Diabetes Mellitus (DM), smoking, dyslipidemy, CV disease family history (FH) and nephropathy. The analysis and processing of the data were performed in the software EpiInfo.
13