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Heart transplantation
11.
12. 13. 14. 15.
Meisner H. Long-term results after repair of complete atrioventricular septal defects: analysis of risk factors. Ann Thorac Surg 1998;65:754 –60. Alexi-Meskishvili V, Ishino K, Dahnert I, et al. Correction of complete atrioventricular septal defects with the doublepatch technique and cleft closure. Ann Thorac Surg 1996;62: 519 –25. Hanley FL, Fenton KN, Jonas RA, et al. Surgical repair of complete atrioventricular canal defects in infancy. J Thorac Cardiovasc Surg 1993;106:388 –97. Suzuki K, Tatsuno K, Kikuchi T, Mimori S. Predisposing factors of valve regurgitation in complete atrioventricular septal defect. J Am Coll Cardiol 1998;32:1449 –53. Reller MD, Morris CD. Is Down syndrome a risk factor for poor outcome after repair of congenital heart defects? J Pediatr 1998;132:738 –41. Tubman TRJ, Shields MD, Craig BG, Nevin NC. Congenital heart disease in Down’s syndrome: two year prospective early screening study. BMJ 1991;302:1425–7.
AL-HAY ET AL COMPLETE AVSD AND SURGICAL OUTCOME
421
16. Rudolph AM. The changes in the circulation after birth; their importance in congenital heart disease. Circulation 1970;41: 343–59. 17. Clapp S, Perry BL, Farooki ZQ, et al. Down’s syndrome, complete atrioventricular canal, and pulmonary vascular obstructive disease. J Thorac Cardiovasc Sur 1990;100:115–21. 18. Clapp SK, Perry BL, Farooki ZQ, et al. Surgical and medical results of complete atrioventricular canal: a ten year review. Am J Cardiol 1987;59:454 –8. 19. Lee CN, Danielson GK, Schaff HV, et al. Surgical treatment of double orifice mitral valve in atrioventricular canal defects. J Thorac Cardiovasc Surg 1985;90:700 –5. 20. Studer M, Blackstone EH, Kirklin JW, et al. Determinants of early and late results of repair of atrioventricular septal (canal) defect. J Thorac Cardiovasc Surg 1982;84:523–42. 21. Haworth SG. Pulmonary vascular bed in children with complete atrioventricular septal defect: relation between structural and hemodynamic abnormalities. Am J Cardiol 1986;57:833–9.
REVIEW OF RECENT BOOKS Heart Transplantation By James K. Kirklin, MD, James B. Young, MD, and David C. McGiffin, MD 2002, London, England, Churchill Livingstone, Inc 650 pp, illustrated, $229.00 ISBN: 0443076553 Reviewed by Bartley P. Griffith, MD This text is the best of its kind. The reason it works so well is that it is a comprehensive text from a single center that works cohesively to explain history, science, and procedure and outcomes in cardiac transplantation. I am jealous of the Alabama group for their thoughtfulness in putting this together and of Jim Young for his strong contributions based upon his lifelong dedication to the medical therapy of those afflicted with endstage heart disease. This book literally drew me in. I have, over a period of more than 25 years, read most of the chapters and short referenced texts on cardiac transplantation. None of them “hit the spot” as this one did. The editors have included authors of great experience who again fit well into the whole of the textbook, providing the reader with a continuity of style and approach that is nonrepetitive and certainly builds throughout. This text is very readable for nurses, administrators, surgeons, residents, coordinators, and even in some sense patients. As I read through each chapter, I attempted to be critical relative to the length of the chapter, the topics it covered, and its currency. I literally found no objections. I generally learned a great deal from each chapter in spite of the topic. I found myself back in college days reviewing statistics and math presented in Chapter Three entitled “Methodology for Clinical Research in Cardiac Transplantation.” This chapter, of course, while bracketed around transplantation is valuable for all medical practitioners, and especially surgeons, who deal with rates of survival, comparison groups, cohort studies, etc. I found that the data were presented in an extremely clear way and one that, with a few repeated readings, was easy to remember.
© 2003 by The Society of Thoracic Surgeons Published by Elsevier Science Inc
“Immunosuppresive Modalities,” Chapter 13, is a very important chapter dedicated to an evaluation of various immunosuppressive medications, their interactions, and their overall application in cardiac transplantation. This chapter is jam-packed with clinically relative information and a must for those involved in the care of these patients. The old days of a cookbook of non-varied immunosuppressive therapies good for all patients is probably in the past. Various medications are now available, each with their own toxicities, so that a variety of approaches should be undertaken based on the patient’s needs and responses. This chapter does a good job at introducing the clinician to the basics. One slight omission appears to be the important area of drug interaction that invariably affects all of our recipients at one point or another. It would have been helpful if the Immunosuppressive Modalities chapter would have included a bit more in the clinically relevant area of multiple drug use and multiple drug interactions. Chapter 15 discusses infections after heart and lung transplantation, and again hits the mark in terms of being an exhaustive reference for practitioners. It is especially useful as a roadmap for potential therapy and prophylaxis, and it appears to me to be especially good in the area of cytomegalic virus. Cytomegalic virus continues to be a problem, but with preemptive monitoring and new oral antibiotics it may evolve to a less threatening problem. In summary, this is a reference text that needs not only to sit on the shelves of all practitioners interested in heart transplantation, but also needs to be read in its entirety many times. It is an example of three authors who have dedicated much of their lives to this area and who have recruited first-rate contributors to help those of us toiling in this field to understand a little bit better how to help the patients who are so much in need. We as a specialty should be thankful that so much time and effort was put forward by those responsible for this exemplary text. Baltimore, Maryland
Ann Thorac Surg 2003;75:421
● 0003-4975/03/$30.00 PII S0003-4975(02)4573-3
CARDIOVASCULAR
Ann Thorac Surg 2003;75:412–21
12. 13. 14. 15.
Meisner H. Long-term results after repair of complete atrioventricular septal defects: analysis of risk factors. Ann Thorac Surg 1998;65:754 –60. Alexi-Meskishvili V, Ishino K, Dahnert I, et al. Correction of complete atrioventricular septal defects with the doublepatch technique and cleft closure. Ann Thorac Surg 1996;62: 519 –25. Hanley FL, Fenton KN, Jonas RA, et al. Surgical repair of complete atrioventricular canal defects in infancy. J Thorac Cardiovasc Surg 1993;106:388 –97. Suzuki K, Tatsuno K, Kikuchi T, Mimori S. Predisposing factors of valve regurgitation in complete atrioventricular septal defect. J Am Coll Cardiol 1998;32:1449 –53. Reller MD, Morris CD. Is Down syndrome a risk factor for poor outcome after repair of congenital heart defects? J Pediatr 1998;132:738 –41. Tubman TRJ, Shields MD, Craig BG, Nevin NC. Congenital heart disease in Down’s syndrome: two year prospective early screening study. BMJ 1991;302:1425–7.
AL-HAY ET AL COMPLETE AVSD AND SURGICAL OUTCOME
421
16. Rudolph AM. The changes in the circulation after birth; their importance in congenital heart disease. Circulation 1970;41: 343–59. 17. Clapp S, Perry BL, Farooki ZQ, et al. Down’s syndrome, complete atrioventricular canal, and pulmonary vascular obstructive disease. J Thorac Cardiovasc Sur 1990;100:115–21. 18. Clapp SK, Perry BL, Farooki ZQ, et al. Surgical and medical results of complete atrioventricular canal: a ten year review. Am J Cardiol 1987;59:454 –8. 19. Lee CN, Danielson GK, Schaff HV, et al. Surgical treatment of double orifice mitral valve in atrioventricular canal defects. J Thorac Cardiovasc Surg 1985;90:700 –5. 20. Studer M, Blackstone EH, Kirklin JW, et al. Determinants of early and late results of repair of atrioventricular septal (canal) defect. J Thorac Cardiovasc Surg 1982;84:523–42. 21. Haworth SG. Pulmonary vascular bed in children with complete atrioventricular septal defect: relation between structural and hemodynamic abnormalities. Am J Cardiol 1986;57:833–9.
REVIEW OF RECENT BOOKS Heart Transplantation By James K. Kirklin, MD, James B. Young, MD, and David C. McGiffin, MD 2002, London, England, Churchill Livingstone, Inc 650 pp, illustrated, $229.00 ISBN: 0443076553 Reviewed by Bartley P. Griffith, MD This text is the best of its kind. The reason it works so well is that it is a comprehensive text from a single center that works cohesively to explain history, science, and procedure and outcomes in cardiac transplantation. I am jealous of the Alabama group for their thoughtfulness in putting this together and of Jim Young for his strong contributions based upon his lifelong dedication to the medical therapy of those afflicted with endstage heart disease. This book literally drew me in. I have, over a period of more than 25 years, read most of the chapters and short referenced texts on cardiac transplantation. None of them “hit the spot” as this one did. The editors have included authors of great experience who again fit well into the whole of the textbook, providing the reader with a continuity of style and approach that is nonrepetitive and certainly builds throughout. This text is very readable for nurses, administrators, surgeons, residents, coordinators, and even in some sense patients. As I read through each chapter, I attempted to be critical relative to the length of the chapter, the topics it covered, and its currency. I literally found no objections. I generally learned a great deal from each chapter in spite of the topic. I found myself back in college days reviewing statistics and math presented in Chapter Three entitled “Methodology for Clinical Research in Cardiac Transplantation.” This chapter, of course, while bracketed around transplantation is valuable for all medical practitioners, and especially surgeons, who deal with rates of survival, comparison groups, cohort studies, etc. I found that the data were presented in an extremely clear way and one that, with a few repeated readings, was easy to remember.
© 2003 by The Society of Thoracic Surgeons Published by Elsevier Science Inc
“Immunosuppresive Modalities,” Chapter 13, is a very important chapter dedicated to an evaluation of various immunosuppressive medications, their interactions, and their overall application in cardiac transplantation. This chapter is jam-packed with clinically relative information and a must for those involved in the care of these patients. The old days of a cookbook of non-varied immunosuppressive therapies good for all patients is probably in the past. Various medications are now available, each with their own toxicities, so that a variety of approaches should be undertaken based on the patient’s needs and responses. This chapter does a good job at introducing the clinician to the basics. One slight omission appears to be the important area of drug interaction that invariably affects all of our recipients at one point or another. It would have been helpful if the Immunosuppressive Modalities chapter would have included a bit more in the clinically relevant area of multiple drug use and multiple drug interactions. Chapter 15 discusses infections after heart and lung transplantation, and again hits the mark in terms of being an exhaustive reference for practitioners. It is especially useful as a roadmap for potential therapy and prophylaxis, and it appears to me to be especially good in the area of cytomegalic virus. Cytomegalic virus continues to be a problem, but with preemptive monitoring and new oral antibiotics it may evolve to a less threatening problem. In summary, this is a reference text that needs not only to sit on the shelves of all practitioners interested in heart transplantation, but also needs to be read in its entirety many times. It is an example of three authors who have dedicated much of their lives to this area and who have recruited first-rate contributors to help those of us toiling in this field to understand a little bit better how to help the patients who are so much in need. We as a specialty should be thankful that so much time and effort was put forward by those responsible for this exemplary text. Baltimore, Maryland
Ann Thorac Surg 2003;75:421
● 0003-4975/03/$30.00 PII S0003-4975(02)4573-3
CARDIOVASCULAR
Ann Thorac Surg 2003;75:412–21