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Hemorrhage following toxemia
.\m. I. Ob,t. & (~I'll<'<·. Mav, I'I~H
!I HI
a release of toxin. 'l'he premature aging of the toxemie placenta collaborates and is u pari of the events described above. 'l~he toxin liberated from the endometrium after prematur(' estrogen and progesterone withdrawal is similar to the menstrual toxin resulting from tissue break-down in the normal menstrual cycle. 'l'he elevation of chorionic gonadotropin result,from the failure of the aging syncytium to perform its normal function of utilizing it in th<' production of estrogen and progesterone. It is concluded that late toxemias of pregnaucy are the result of a tissue toxin which results from tissuP neero~is in the tlecidua following \VrLLIAM HWKJCRS. premature withdrawal of estrogen and progesterone. Brouse, L. T.: Hemorrhage Following Toxemia, Obst. y Ginec. Latino-Am. 4:
i-49-itl~,
1\140.
The author maintains that in the pre~ence of toxemia, with its associated edema, tiltuterine musculature undergoes changes which result in dissociation of the fibers. The uterus therefore becomes atonic, and there is inertia during labor. During the third stage the inertia may result in hemorrhage, with consequent severe anemia and even death. At the El Salvador Maternity the mortality from the inertia and hemorrhage which result from toxemia was 10.1 per cent. The author believes that the association of toxemia and uterine inertia with hemor· rhage is much more frequent than is generally admitted. There is no relationship hetwe<'n the severity of the toxemia and the degree of atony of the uterus or amount of bleeding. The author favors expectant and conservative therapy for toxemia ehiefly in the form of sedation, blood transfusion and medical induction of labor by the method of Kreis. ·
.T. P.
GR~;ENJJlLL.
Venereal Disease Becker, S. William: Practical Aspects of Verification Tests for Syphilis in Office Practice, Am. J. Syph. Gonor. & Ven. Dis. 31: 225, 1947. The author concludes that on the basis of a small sm·ies of cases, the Kahn verification procedures seem to support the multiple diagnostic attack of Stokes in evaluation of positive blood tests as seen in private syphilologic practice. They are not recommended for the nonsyphilologist. The use of cardiolipin and purified leeithin (Pangborn) and use of newer chemical methods devised by Neurath promise to be of even greater assistanee in identification of nonspecifie positive blood tests. C. 0. MALAND. Callaway, J. Lamar: The Weltmann Serum Coagulation Reaction in Syphilis, Am .•r. Ayph. Gonor. & Ven. Dis. 31: 216, 1947. The author summarizes the article as follows: (1) The results of the ·welt mann serum coagulation reaction in 610 patients with syphilis are given. (2) With the exception of thirty·four patients with prenatal syphilis, the Weltmann coagulation reaction band was either normal or revealed a tendency toward moderate but distinct shift to the right with a pro· longation of the coagulation band. ( 3) Thirty-two patients with early syphilis received six months' treatment with an arsenical and bismuth, without appreciable change in the Welt· mann coagulation band. ( 4) }'ever therapy and penicillin therapy in patients with syphilis of the. central nervous system exerted no specific effect on the Weltmann coagulation reaction band. (5) Sex or race seemed to exert no effect on the Weltmann reaction band in this study. C. 0. MALAND.
!I HI
a release of toxin. 'l'he premature aging of the toxemie placenta collaborates and is u pari of the events described above. 'l~he toxin liberated from the endometrium after prematur(' estrogen and progesterone withdrawal is similar to the menstrual toxin resulting from tissue break-down in the normal menstrual cycle. 'l'he elevation of chorionic gonadotropin result,from the failure of the aging syncytium to perform its normal function of utilizing it in th<' production of estrogen and progesterone. It is concluded that late toxemias of pregnaucy are the result of a tissue toxin which results from tissuP neero~is in the tlecidua following \VrLLIAM HWKJCRS. premature withdrawal of estrogen and progesterone. Brouse, L. T.: Hemorrhage Following Toxemia, Obst. y Ginec. Latino-Am. 4:
i-49-itl~,
1\140.
The author maintains that in the pre~ence of toxemia, with its associated edema, tiltuterine musculature undergoes changes which result in dissociation of the fibers. The uterus therefore becomes atonic, and there is inertia during labor. During the third stage the inertia may result in hemorrhage, with consequent severe anemia and even death. At the El Salvador Maternity the mortality from the inertia and hemorrhage which result from toxemia was 10.1 per cent. The author believes that the association of toxemia and uterine inertia with hemor· rhage is much more frequent than is generally admitted. There is no relationship hetwe<'n the severity of the toxemia and the degree of atony of the uterus or amount of bleeding. The author favors expectant and conservative therapy for toxemia ehiefly in the form of sedation, blood transfusion and medical induction of labor by the method of Kreis. ·
.T. P.
GR~;ENJJlLL.
Venereal Disease Becker, S. William: Practical Aspects of Verification Tests for Syphilis in Office Practice, Am. J. Syph. Gonor. & Ven. Dis. 31: 225, 1947. The author concludes that on the basis of a small sm·ies of cases, the Kahn verification procedures seem to support the multiple diagnostic attack of Stokes in evaluation of positive blood tests as seen in private syphilologic practice. They are not recommended for the nonsyphilologist. The use of cardiolipin and purified leeithin (Pangborn) and use of newer chemical methods devised by Neurath promise to be of even greater assistanee in identification of nonspecifie positive blood tests. C. 0. MALAND. Callaway, J. Lamar: The Weltmann Serum Coagulation Reaction in Syphilis, Am .•r. Ayph. Gonor. & Ven. Dis. 31: 216, 1947. The author summarizes the article as follows: (1) The results of the ·welt mann serum coagulation reaction in 610 patients with syphilis are given. (2) With the exception of thirty·four patients with prenatal syphilis, the Weltmann coagulation reaction band was either normal or revealed a tendency toward moderate but distinct shift to the right with a pro· longation of the coagulation band. ( 3) Thirty-two patients with early syphilis received six months' treatment with an arsenical and bismuth, without appreciable change in the Welt· mann coagulation band. ( 4) }'ever therapy and penicillin therapy in patients with syphilis of the. central nervous system exerted no specific effect on the Weltmann coagulation reaction band. (5) Sex or race seemed to exert no effect on the Weltmann reaction band in this study. C. 0. MALAND.