- Email: [email protected]
Heparinization of the central venous catheter in dogs undergoing hemodialysis
S42
Abstracts / Journal of Biotechnology 208 (2015) S5–S120
Study on hourly average frequency of behavioural manifestations during autumn season of the New Zealand White and Californian rabbit breeds Nicolae Stanciu ∗ , Elena Popescu Miclosanu, Madalin Gavrila Faculty of Animal Science, University of Agronomic Sciences and Veterinary Medicine, Bucharest, Romania
used, 15 cm in length, with a 120 ml/min blood flow rate. In patients weighing between 16 and 30 kg, 12Fr catheters were used, 20 cm in length, with a 240 ml/min blood flow rate. In patients weighing over 30 kg, best results were reached by using bigger catheters, 14Fr, 20 cm in length and with a 400 ml/min blood flow rate. The length and the diameter of the catheter, alongside the pattern for proximal and distal openings play a major part in the patient’s comfort, the quality of the hemodialysis and the reached results. http://dx.doi.org/10.1016/j.jbiotec.2015.06.119
E-mail address: stanciu [email protected] (N. Stanciu). Studies on rabbit behaviour as an indicator of their welfare are incomplete, contradictory and represented the concern of a small number of researchers, who, in general, did not take into account the production issues involved; therefore, an ethological research was conducted, considering the fall season conditions, on 16 New Zealand White and Californian rabbits, for 20 days, under environmental conditions provided by literature. They were monitored based on ethological records specific to rabbits, in 10 hourly intervals, between 8 a.m. and 6 p.m. The research shows that the highest hourly average frequency of feeding was recorded in the New Zealand White females (1.63 ± 0.05), 17.2% higher than in the Californian females, and the lowest in the New Zealand White males (1.14 ± 0.03). Regarding the exploratory behaviour, Californian males (1.00 ± 0.61) and females (1.15 ± 0.03) were more active, showing hourly frequency higher than the New Zealand White males (0.75 ± 0.02) and females (0.24 ± 0.03). The males and females in both breeds performed hygiene activities with approximately the same hourly frequency. Both the New Zealand White females (1.26 ± 0.03) and Californian females (1.22 ± 0.04) showed hourly frequency of rest in standing position, supported on their hindquarters, higher than the New Zealand White males (0.87 ± 0.02) and Californian males (0.99 ± 0.47). Abnormal behaviours were infrequent, especially in males of both breeds. Acknowledgement: This paper was published under the frame of European Social Found, Human Resources Development Operational Programe 2007-2013, project no. POSDRU/159/1.5/S/132765.
Heparinization of the central venous catheter in dogs undergoing hemodialysis Balascau Stefanita Bogdan ∗ , Alexandru Bociu, C˘at˘alin Ivas¸cu, C˘at˘alin Mics¸a, Bogdan Alexandru Vit¸a˘ laru Department of Clinical Sciences, University of Agricultural Sciences and Veterinary Medicine, Bucharest, Romania E-mail address: [email protected] (B. S. Bogdan). This study was conducted on 18 dogs, aged between 5 and 15 years, weighing between 21 and 55 kg, during 12 months. High flux two way polyurethane catheters were used. The catheters were 20 cm in length, 12Fr in diameter, radio-opaque, soft tipped, nontraumatic, with markings for length and sutures. The catheters were kept in place in between 7 and 21 days. Three catheter heparinization methods were used, employing unfractionated heparin. The first one was to introduce the unfractionated heparin solution 500 IU/ml along the entire length of the catheter every 4 h. The second one was to introduce an undiluted unfractionated heparin solution 1000 IU/ml every 12 h. The third one consisted of introducing an unfractionated heparin solution 5000 IU/ml every 24 h. In all methods, the heparin was sucked on the catheter along with 1 ml of blood through both openings. Following this, the openings were cleaned with physiological saline serum 0.9% before introducing a new dose. Best results were attained when using unfractionated heparin 5000 IU/ml every 24 h. Catheters that were heparinized thus could be used up to 21 days with a maximum of 30% change in the maximum flow rate during the last day of use.
http://dx.doi.org/10.1016/j.jbiotec.2015.06.118 http://dx.doi.org/10.1016/j.jbiotec.2015.06.120 Choosing the central venous catheter in order to perform hemodialysis in dog S¸tef˘anit¸a˘ Bogdan B˘al˘as¸c˘au ∗ , Alexandru Bociu, C˘at˘alin Ivas¸cu, C˘at˘alin Mics¸a, Bogdan Alexandru Vit¸a˘ laru Department of Clinical Sciences, University of Agricultural Sciences and Veterinary Medicine, Bucharest, Romania E-mail address: [email protected] (S¸.B. B˘al˘as¸c˘au). This study has been conducted on 24 dogs, aged between 5 months and 15 years, weighing between 10 and 55 kg during a period of twelve months. High flux two way catheters were used. These were radio-opaque, titanium made, soft tipped, non-traumatic, with markings for length and sutures. The blood flow during dialysis ranged between 3 ml/kg/min up to a maximum flow rate of 10–12 ml/kg/min, only if the patient’s starting BUN level and vascular access can tolerate such a rate. We selected the length of the catheter by measuring from the expected insertion point to the junction of the cranial vena cava and right atrium of the patient. For patients weighing between 10 and 15 kg, 9Fr catheters were
Propofol induction anesthesia for central venous catheterization in dogs with renal failure Ruxandra Costea, Bogdan Alexandru Vitalaru ∗ Faculty of Veterinary Medicine, Bucharest, Romania E-mail address: [email protected] (B. A. Vitalaru). Safe anesthesia and intensive care management require an understanding of the pathophysiology of kidney disease in order to prevent aggravation of pre-existing conditions. Complications in renal failure present the anaesthetist with a number of clinical challenges related to altered anaesthetic dosages and to difficult vascular access and fluid balance. We analyzed two groups. The first group consisted of 30 cases (dogs, 7–50 kg) scheduled for CVC (central venous catheterization), in order to undergo hemodialysis. Anesthesia was induced with propofol i.v. for 15 minutes. The second group was a control group of 30 dogs, evaluated as ASA1 patients (with low anesthetic risk). Anesthesia was induced with propofol. The induction propofol dose was significantly higher in patients with renal failure as compared to the control group:
Abstracts / Journal of Biotechnology 208 (2015) S5–S120
Study on hourly average frequency of behavioural manifestations during autumn season of the New Zealand White and Californian rabbit breeds Nicolae Stanciu ∗ , Elena Popescu Miclosanu, Madalin Gavrila Faculty of Animal Science, University of Agronomic Sciences and Veterinary Medicine, Bucharest, Romania
used, 15 cm in length, with a 120 ml/min blood flow rate. In patients weighing between 16 and 30 kg, 12Fr catheters were used, 20 cm in length, with a 240 ml/min blood flow rate. In patients weighing over 30 kg, best results were reached by using bigger catheters, 14Fr, 20 cm in length and with a 400 ml/min blood flow rate. The length and the diameter of the catheter, alongside the pattern for proximal and distal openings play a major part in the patient’s comfort, the quality of the hemodialysis and the reached results. http://dx.doi.org/10.1016/j.jbiotec.2015.06.119
E-mail address: stanciu [email protected] (N. Stanciu). Studies on rabbit behaviour as an indicator of their welfare are incomplete, contradictory and represented the concern of a small number of researchers, who, in general, did not take into account the production issues involved; therefore, an ethological research was conducted, considering the fall season conditions, on 16 New Zealand White and Californian rabbits, for 20 days, under environmental conditions provided by literature. They were monitored based on ethological records specific to rabbits, in 10 hourly intervals, between 8 a.m. and 6 p.m. The research shows that the highest hourly average frequency of feeding was recorded in the New Zealand White females (1.63 ± 0.05), 17.2% higher than in the Californian females, and the lowest in the New Zealand White males (1.14 ± 0.03). Regarding the exploratory behaviour, Californian males (1.00 ± 0.61) and females (1.15 ± 0.03) were more active, showing hourly frequency higher than the New Zealand White males (0.75 ± 0.02) and females (0.24 ± 0.03). The males and females in both breeds performed hygiene activities with approximately the same hourly frequency. Both the New Zealand White females (1.26 ± 0.03) and Californian females (1.22 ± 0.04) showed hourly frequency of rest in standing position, supported on their hindquarters, higher than the New Zealand White males (0.87 ± 0.02) and Californian males (0.99 ± 0.47). Abnormal behaviours were infrequent, especially in males of both breeds. Acknowledgement: This paper was published under the frame of European Social Found, Human Resources Development Operational Programe 2007-2013, project no. POSDRU/159/1.5/S/132765.
Heparinization of the central venous catheter in dogs undergoing hemodialysis Balascau Stefanita Bogdan ∗ , Alexandru Bociu, C˘at˘alin Ivas¸cu, C˘at˘alin Mics¸a, Bogdan Alexandru Vit¸a˘ laru Department of Clinical Sciences, University of Agricultural Sciences and Veterinary Medicine, Bucharest, Romania E-mail address: [email protected] (B. S. Bogdan). This study was conducted on 18 dogs, aged between 5 and 15 years, weighing between 21 and 55 kg, during 12 months. High flux two way polyurethane catheters were used. The catheters were 20 cm in length, 12Fr in diameter, radio-opaque, soft tipped, nontraumatic, with markings for length and sutures. The catheters were kept in place in between 7 and 21 days. Three catheter heparinization methods were used, employing unfractionated heparin. The first one was to introduce the unfractionated heparin solution 500 IU/ml along the entire length of the catheter every 4 h. The second one was to introduce an undiluted unfractionated heparin solution 1000 IU/ml every 12 h. The third one consisted of introducing an unfractionated heparin solution 5000 IU/ml every 24 h. In all methods, the heparin was sucked on the catheter along with 1 ml of blood through both openings. Following this, the openings were cleaned with physiological saline serum 0.9% before introducing a new dose. Best results were attained when using unfractionated heparin 5000 IU/ml every 24 h. Catheters that were heparinized thus could be used up to 21 days with a maximum of 30% change in the maximum flow rate during the last day of use.
http://dx.doi.org/10.1016/j.jbiotec.2015.06.118 http://dx.doi.org/10.1016/j.jbiotec.2015.06.120 Choosing the central venous catheter in order to perform hemodialysis in dog S¸tef˘anit¸a˘ Bogdan B˘al˘as¸c˘au ∗ , Alexandru Bociu, C˘at˘alin Ivas¸cu, C˘at˘alin Mics¸a, Bogdan Alexandru Vit¸a˘ laru Department of Clinical Sciences, University of Agricultural Sciences and Veterinary Medicine, Bucharest, Romania E-mail address: [email protected] (S¸.B. B˘al˘as¸c˘au). This study has been conducted on 24 dogs, aged between 5 months and 15 years, weighing between 10 and 55 kg during a period of twelve months. High flux two way catheters were used. These were radio-opaque, titanium made, soft tipped, non-traumatic, with markings for length and sutures. The blood flow during dialysis ranged between 3 ml/kg/min up to a maximum flow rate of 10–12 ml/kg/min, only if the patient’s starting BUN level and vascular access can tolerate such a rate. We selected the length of the catheter by measuring from the expected insertion point to the junction of the cranial vena cava and right atrium of the patient. For patients weighing between 10 and 15 kg, 9Fr catheters were
Propofol induction anesthesia for central venous catheterization in dogs with renal failure Ruxandra Costea, Bogdan Alexandru Vitalaru ∗ Faculty of Veterinary Medicine, Bucharest, Romania E-mail address: [email protected] (B. A. Vitalaru). Safe anesthesia and intensive care management require an understanding of the pathophysiology of kidney disease in order to prevent aggravation of pre-existing conditions. Complications in renal failure present the anaesthetist with a number of clinical challenges related to altered anaesthetic dosages and to difficult vascular access and fluid balance. We analyzed two groups. The first group consisted of 30 cases (dogs, 7–50 kg) scheduled for CVC (central venous catheterization), in order to undergo hemodialysis. Anesthesia was induced with propofol i.v. for 15 minutes. The second group was a control group of 30 dogs, evaluated as ASA1 patients (with low anesthetic risk). Anesthesia was induced with propofol. The induction propofol dose was significantly higher in patients with renal failure as compared to the control group: