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Hereditary factors in Pierre Robin syndrome
670
ABSTRACTS
in pH and blood gas tensions occurred early, before similar changes in other vital parameMUSCLESURFACEPH: A NEW PARAMETER ters. This technic seemed to be a simple IN THE MONITORING OF THE CRITICALLY and reliable method of monitoring critically ill infants and children undergoing major ILL CHILD. R. Filler and J. DOS. Pedisurgery.-A. M. Salzberg atrics 47:88&885 (May) 1971.
GENERAL
CONSIDERATIONS
Three children who were recovering from major abdominal surgery and were monitored by conventional methods also had muscle surface pH recorded continuously, with a new miniaturized pH electrode, for a prolonged period of time. The clinical findings correlate with experimental results and indicate that muscle pH is a reflection of both arterial pH and the adequacy of tissue perfusion. Further trials in monitoring severely sick infants using muscle surface pH seems to be indicated.-C. L. Rabin
HEAD AND NECK GIAW~ORCANOID NAEVUSOF THE FACE ANI) SCALP IN A NEWBORNINFANT.H. Plunel, J. Gaubert, A. Bazex, X. Floutard, and P. Colombies. Arm. Chir. Infant, 11:243-
254, 1970.
The authors describe the case of a newborn infant with an organoid naevus of the face and scalp of complex histological composition. The lesion can be classified as an organoid hamartoma, based on a dysgenesis MONITORING VENOUSPH ANDGAS TENSIONS of the primary epithelial buds and preferenDURING OPERATIONSON INFANTS AND tially situated in the face and in the scalp. The clinical evolution involves three phases. CHILDREN. Jay L. Grosfeld, James A. From birth to puberty the hamartomatous ONeill, Jr., E. Thomas Boles, Jr., and lesion presents as a yellowish brilliant aloH. William Clotworthy, Jr. Arch Surg. pecic plaque. After puberty the lesion belOCb584-588 (May) 1970. comes papillomatous and develops a rough surface. In the stage of adolescence one may Serial monitoring of pH, PO,, Pco,, and observe tumorous vegetations. Neoplastic CO, content were performed in 50 infants transformation presents as an ulcerative and children prior to and during general lesion, The case described in this paper is surgical operations on heparinized mixed of interest insofar as the stage of vegetation venous blood drawn through a cutdown and ulceration was observed at birth. Furcatheter inserted through the external juguthermore, a chromosomal anomaly was demlar vein and passed into the right atrium. onstrated. The risk of developing basocellular Nine neonates had abnormalities picked epithelioma in later stages is a strong indiup preoperatively by this method and abnorcation for radical surgical removal of the mal values were observed during operation lesion.-A. Zimmerman in 34 patients. Twenty-three of 27 neonates with congenital anomalies had abnormalities HEREDITARY FACTORSIN PIERREROBINSYNmeasured, and all of these had operations on DROME.D. B. Carroll, R. A. Peterson, E. W. an emergency basis. Twenty-five of the 34 Wotion, and L. M. Birnbaum. Brit. J. patients in whom abnormalities were noted Plast. Surg. 24:43-50 (January) 1971. during operation had acidosis, whereas nine were alkalotic. Forty-seven cases of the Pierre Robin synMany investigators feel that mixed venous drome are described. All but one had a cleft blood samples provide a reliable, clinical palate and 14 had a family background of indication of pH and Pco, with values comparable to those obtained in arterial blood. this syndrome. Nine families are presented, including 17 cases. There is also a high Abnormalities noted by this technic, such as acidosis and alkalosis, during an operative incidence of cleft palate and cleft lip and procedure could be corrected immediately, complete clefts without micrognathos in the prior to further deterioration of the patient’s families. Chromosome studies in three cases condition. In addition, aberrations in cardiac were normal.-A. Jolleys output and ventilation in newborns and older infants undergoing major operative proceTHYROIDCARCINOMA ORIGINATING IN THYdures were noted and such changes reflected ROGLOSSAL CYST: REPORT OF A CASE.
ABSTRACTS
in pH and blood gas tensions occurred early, before similar changes in other vital parameMUSCLESURFACEPH: A NEW PARAMETER ters. This technic seemed to be a simple IN THE MONITORING OF THE CRITICALLY and reliable method of monitoring critically ill infants and children undergoing major ILL CHILD. R. Filler and J. DOS. Pedisurgery.-A. M. Salzberg atrics 47:88&885 (May) 1971.
GENERAL
CONSIDERATIONS
Three children who were recovering from major abdominal surgery and were monitored by conventional methods also had muscle surface pH recorded continuously, with a new miniaturized pH electrode, for a prolonged period of time. The clinical findings correlate with experimental results and indicate that muscle pH is a reflection of both arterial pH and the adequacy of tissue perfusion. Further trials in monitoring severely sick infants using muscle surface pH seems to be indicated.-C. L. Rabin
HEAD AND NECK GIAW~ORCANOID NAEVUSOF THE FACE ANI) SCALP IN A NEWBORNINFANT.H. Plunel, J. Gaubert, A. Bazex, X. Floutard, and P. Colombies. Arm. Chir. Infant, 11:243-
254, 1970.
The authors describe the case of a newborn infant with an organoid naevus of the face and scalp of complex histological composition. The lesion can be classified as an organoid hamartoma, based on a dysgenesis MONITORING VENOUSPH ANDGAS TENSIONS of the primary epithelial buds and preferenDURING OPERATIONSON INFANTS AND tially situated in the face and in the scalp. The clinical evolution involves three phases. CHILDREN. Jay L. Grosfeld, James A. From birth to puberty the hamartomatous ONeill, Jr., E. Thomas Boles, Jr., and lesion presents as a yellowish brilliant aloH. William Clotworthy, Jr. Arch Surg. pecic plaque. After puberty the lesion belOCb584-588 (May) 1970. comes papillomatous and develops a rough surface. In the stage of adolescence one may Serial monitoring of pH, PO,, Pco,, and observe tumorous vegetations. Neoplastic CO, content were performed in 50 infants transformation presents as an ulcerative and children prior to and during general lesion, The case described in this paper is surgical operations on heparinized mixed of interest insofar as the stage of vegetation venous blood drawn through a cutdown and ulceration was observed at birth. Furcatheter inserted through the external juguthermore, a chromosomal anomaly was demlar vein and passed into the right atrium. onstrated. The risk of developing basocellular Nine neonates had abnormalities picked epithelioma in later stages is a strong indiup preoperatively by this method and abnorcation for radical surgical removal of the mal values were observed during operation lesion.-A. Zimmerman in 34 patients. Twenty-three of 27 neonates with congenital anomalies had abnormalities HEREDITARY FACTORSIN PIERREROBINSYNmeasured, and all of these had operations on DROME.D. B. Carroll, R. A. Peterson, E. W. an emergency basis. Twenty-five of the 34 Wotion, and L. M. Birnbaum. Brit. J. patients in whom abnormalities were noted Plast. Surg. 24:43-50 (January) 1971. during operation had acidosis, whereas nine were alkalotic. Forty-seven cases of the Pierre Robin synMany investigators feel that mixed venous drome are described. All but one had a cleft blood samples provide a reliable, clinical palate and 14 had a family background of indication of pH and Pco, with values comparable to those obtained in arterial blood. this syndrome. Nine families are presented, including 17 cases. There is also a high Abnormalities noted by this technic, such as acidosis and alkalosis, during an operative incidence of cleft palate and cleft lip and procedure could be corrected immediately, complete clefts without micrognathos in the prior to further deterioration of the patient’s families. Chromosome studies in three cases condition. In addition, aberrations in cardiac were normal.-A. Jolleys output and ventilation in newborns and older infants undergoing major operative proceTHYROIDCARCINOMA ORIGINATING IN THYdures were noted and such changes reflected ROGLOSSAL CYST: REPORT OF A CASE.